Does Vitamin C Deficiency Affect Cognitive Development and Function?

Plasma vitamin C concentrations predict risk of incident stroke over 10 y in 20 649 participants of the European Prospective Investigation into Cancer–Norfolk prospective population study

(2018) Phyo K Myint et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Ascorbic Acid and Rates of Cognitive Decline in Alzheimer's Disease

(2017) Gene L. Bowman et al.   JOURNAL OF ALZHEIMERS DISEASE

Influence of vitamin C on markers of oxidative stress in the earliest period of ischemic stroke

(2014) Monika Lagowska-Lenard et al.   Pharmacological Reports

Orally Administrated Ascorbic Acid Suppresses Neuronal Damage and Modifies Expression of SVCT2 and GLUT1 in the Brain of Diabetic Rats with Cerebral Ischemia-Reperfusion

(2014) Naohiro Iwata et al.   Nutrients

Ascorbic Acid and the Brain: Rationale for the Use against Cognitive Decline

(2014) Fiona Harrison et al.   Nutrients

Vitamin C

(2014) Jens Lykkesfeldt et al.   Advances in Nutrition

The Possible Role of Antioxidant Vitamin C in Alzheimer’s Disease Treatment and Prevention

(2013) Jae-Hyeok Heo et al.   American Journal of Alzheimers Disease and Other Dementias

Does Vitamin C Deficiency Increase Lifestyle-Associated Vascular Disease Progression? Evidence Based on Experimental and Clinical Studies

(2013) Pernille Tveden-Nyborg et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of Vitamin C in the Function of the Vascular Endothelium

(2013) James M. May et al.   ANTIOXIDANTS & REDOX SIGNALING

Prolonged maternal vitamin C deficiency overrides preferential fetal ascorbate transport but does not influence perinatal survival in guinea pigs

(2013) Janne G. Schjoldager et al.   BRITISH JOURNAL OF NUTRITION

Regulation of Vitamin C Homeostasis during Deficiency

(2013) Maiken Lindblad et al.   Nutrients

Ascorbic acid, cognitive function, and Alzheimer's disease: A current review and future direction

(2012) Gene L. Bowman   BIOFACTORS

Authors' Perspective: What is the Optimum Intake of Vitamin C in Humans?

(2012) Balz Frei et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease

(2012) A. Valencia et al.   HUMAN MOLECULAR GENETICS

Behavioral and monoamine changes following severe vitamin C deficiency

(2012) Margaret S. Ward et al.   JOURNAL OF NEUROCHEMISTRY

Effect of One-Year Vitamin C- and E-Supplementation on Cerebrospinal Fluid Oxidation Parameters and Clinical Course in Alzheimer’s Disease

(2012) Sönke Arlt et al.   NEUROCHEMICAL RESEARCH

Maternal Vitamin C Deficiency during Pregnancy Persistently Impairs Hippocampal Neurogenesis in Offspring of Guinea Pigs

(2012) Pernille Tveden-Nyborg et al.   PLoS One

Review of Issue: Alzheimer’s Caregiver’s and Internet-Based Support Services: Do They Work?

(2011) Carol F. Lippa   American Journal of Alzheimers Disease and Other Dementias

Hypertensive disorders in pregnancy and intellectual abilities in the offspring in young adulthood: The Helsinki Birth Cohort Study

(2011) Soile Tuovinen et al.   ANNALS OF MEDICINE

Chronic Vitamin C Deficiency does not Accelerate Oxidative Stress in Ageing Brains of Guinea Pigs

(2011) Pernille Tveden-Nyborg et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Behavioral phenotyping of glutathione-deficient mice: Relevance to schizophrenia and bipolar disorder

(2011) Anita Kulak et al.   BEHAVIOURAL BRAIN RESEARCH

Increased Oxidative Stress Is Responsible for Severer Cerebral Infarction in Stroke-Prone Spontaneously Hypertensive Rats

(2011) Xiu-Hua Zhang et al.   CNS Neuroscience & Therapeutics

Total antioxidant capacity of diet in relation to cognitive function and decline

(2010) Elizabeth E Devore et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Neuronal Death and Oxidative Stress in the Developing Brain

(2010) Chrysanthy Ikonomidou et al.   ANTIOXIDANTS & REDOX SIGNALING

Cellular pathways for transport and efflux of ascorbate and dehydroascorbate

(2010) Alessandro Corti et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents

(2010) Emily Flashman et al.   BIOCHEMICAL JOURNAL

Vitamin C distribution and retention in the mouse brain

(2010) Fiona E. Harrison et al.   BRAIN RESEARCH

Low vitamin C and increased oxidative stress and cell death in mice that lack the sodium-dependent vitamin C transporter SVCT2

(2010) F.E. Harrison et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vitamin C deficiency in early postnatal life impairs spatial memory and reduces the number of hippocampal neurons in guinea pigs

(2009) Pernille Tveden-Nyborg et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Pregnancy-associated Hypertensive Disorders and Adult Cognitive Function Among Danish Conscripts

(2009) V. Ehrenstein et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Ascorbic acid attenuates scopolamine-induced spatial learning deficits in the water maze

(2009) F.E. Harrison et al.   BEHAVIOURAL BRAIN RESEARCH

World Health Organisation multicentre randomised trial of supplementation with vitamins C and E among pregnant women at high risk for pre-eclampsia in populations of low nutritional status from developing countries

(2009) J Villar et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Is vitamin C supplementation beneficial? Lessons learned from randomised controlled trials

(2009) Jens Lykkesfeldt et al.   BRITISH JOURNAL OF NUTRITION

Collagen-related abnormalities, reduction in bone quality, and effects of menatetrenone in rats with a congenital ascorbic acid deficiency

(2009) Kuniko Hara et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Antioxidants and cognitive training interact to affect oxidative stress and memory in APP/PSEN1 mice

(2009) F.E. Harrison et al.   NUTRITIONAL NEUROSCIENCE

Vitamin C reduces spatial learning deficits in middle-aged and very old APP/PSEN1 transgenic and wild-type mice

(2009) F.E. Harrison et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Does vitamin C deficiency result in impaired brain development in infants?

(2009) Pernille Tveden-Nyborg et al.   REDOX REPORT

Ascorbic acid supplementation could affect passive avoidance learning and memory in rat

(2008) Siamak Shahidi et al.   BRAIN RESEARCH BULLETIN

Elevated oxidative stress and sensorimotor deficits but normal cognition in mice that cannot synthesize ascorbic acid

(2008) Fiona E. Harrison et al.   JOURNAL OF NEUROCHEMISTRY

Estimated prevalence and predictors of vitamin C deficiency within UK's low-income population

(2008) A. Mosdol et al.   JOURNAL OF PUBLIC HEALTH

Antioxidant Vitamin Supplement Use and Risk of Dementia or Alzheimer's Disease in Older Adults

(2008) Shelly L. Gray et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY