期刊
BIOFACTORS
卷 38, 期 2, 页码 114-122出版社
WILEY
DOI: 10.1002/biof.1002
关键词
ascorbic acid; vitamin C; cognitive function; Alzheimer's disease; dementia; plasma; CSF; SVCT; blood-brain barrier; blood-CSF barrier; choroid plexus
资金
- NIH/NCCAM [K23AT004777]
This narrative review appraises the human and animal studies implicating ascorbic acid (AA) in normal cognitive function and Alzheimer's disease. A research framework for how nutrition affects brain aging is proposed with emphasis on AA intake, status, metabolism, and transport into brain tissue. A final synopsis highlights areas for future research regarding AA nourishment and healthy brain aging.
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