Dysfunctional autophagy in Alzheimer’s disease: pathogenic roles and therapeutic implications
出版年份 2014 全文链接
标题
Dysfunctional autophagy in Alzheimer’s disease: pathogenic roles and therapeutic implications
作者
关键词
Alzheimer’s disease, autophagy, presenilin, axon, lysosome, animal model
出版物
Neuroscience Bulletin
Volume 30, Issue 2, Pages 308-316
出版商
Springer Nature
发表日期
2014-03-07
DOI
10.1007/s12264-013-1418-8
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
- (2014) Anne Simonsen et al. Autophagy
- Valproic acid reduces autophagy and promotes functional recovery after spinal cord injury in rats
- (2013) Hai-Hu Hao et al. Neuroscience Bulletin
- Guidelines for the use and interpretation of assays for monitoring autophagy
- (2012) Daniel J. Klionsky et al. Autophagy
- Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons
- (2012) Sandra Maday et al. JOURNAL OF CELL BIOLOGY
- Regulation of Presynaptic Neurotransmission by Macroautophagy
- (2012) Daniela Hernandez et al. NEURON
- Neuronal autophagy in cerebral ischemia
- (2012) Feng Xu et al. Neuroscience Bulletin
- Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus
- (2011) Raquel Sanchez-Varo et al. ACTA NEUROPATHOLOGICA
- Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis
- (2011) Dun-Sheng Yang et al. Autophagy
- Autophagy and Aging
- (2011) David C. Rubinsztein et al. CELL
- Presenilin Is Necessary for Efficient Proteolysis through the Autophagy-Lysosome System in a -Secretase-Independent Manner
- (2011) K. M. Neely et al. JOURNAL OF NEUROSCIENCE
- Autophagy failure in Alzheimer's disease—locating the primary defect
- (2011) Ralph A. Nixon et al. NEUROBIOLOGY OF DISEASE
- Deconstruction for Reconstruction: The Role of Proteolysis in Neural Plasticity and Disease
- (2011) Baris Bingol et al. NEURON
- Inducing Autophagy by Rapamycin Before, but Not After, the Formation of Plaques and Tangles Ameliorates Cognitive Deficits
- (2011) Smita Majumder et al. PLoS One
- A comprehensive glossary of autophagy-related molecules and processes
- (2010) Daniel J. Klionsky et al. Autophagy
- Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits
- (2010) Dun-Sheng Yang et al. BRAIN
- Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations
- (2010) Ju-Hyun Lee et al. CELL
- Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau
- (2010) Antonella Caccamo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain
- (2010) Troy T. Rohn et al. NEUROBIOLOGY OF DISEASE
- Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease
- (2010) Patricia Spilman et al. PLoS One
- Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease
- (2010) M. M. Lipinski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autophagy promotes synapse development inDrosophila
- (2009) Wei Shen et al. JOURNAL OF CELL BIOLOGY
- Abeta42-Induced Neurodegeneration via an Age-Dependent Autophagic-Lysosomal Injury in Drosophila
- (2009) Daijun Ling et al. PLoS One
- Autophagy in the Pathogenesis of Disease
- (2008) Beth Levine et al. CELL
- Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease
- (2008) B. Boland et al. JOURNAL OF NEUROSCIENCE
- Autophagy fights disease through cellular self-digestion
- (2008) Noboru Mizushima et al. NATURE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More