Introduction to cell-hydrogel mechanosensing

The influence of substrate stiffness gradients on primary human dermal fibroblasts

(2013) Isabel Hopp et al.   BIOMATERIALS

A comparison of fibrin, agarose and gellan gum hydrogels as carriers of stem cells and growth factor delivery microspheres for cartilage regeneration

(2013) Mark Ahearne et al.   Biomedical Materials

Mesenchymal stem cell durotaxis depends on substrate stiffness gradient strength

(2013) Ludovic G. Vincent et al.   Biotechnology Journal

Designing degradable hydrogels for orthogonal control of cell microenvironments

(2013) Prathamesh M. Kharkar et al.   CHEMICAL SOCIETY REVIEWS

Response of Sheep Chondrocytes to Changes in Substrate Stiffness from 2 to 20 Pa: Effect of Cell Passaging

(2013) Patricia Sanz-Ramos et al.   CONNECTIVE TISSUE RESEARCH

Composite electrospun gelatin fiber-alginate gel scaffolds for mechanically robust tissue engineered cornea

(2013) Khaow Tonsomboon et al.   Journal of the Mechanical Behavior of Biomedical Materials

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

(2013) Sudhir Khetan et al.   NATURE MATERIALS

Evaluation of Physical and Mechanical Properties of Porous Poly (Ethylene Glycol)-co-(L-Lactic Acid) Hydrogels during Degradation

(2013) Yu-Chieh Chiu et al.   PLoS One

Human iPSC-Derived Neural Crest Stem Cells Promote Tendon Repair in a Rat Patellar Tendon Window Defect Model

(2013) Wei Xu et al.   TISSUE ENGINEERING PART A

Peptide hydrogels

(2013) Antara Dasgupta et al.   RSC Advances

Exposure to Carbon Nanotubes Leads to Changes in the Cellular Biomechanics

(2013) Chenbo Dong et al.   Advanced Healthcare Materials

Integration and Regression of Implanted Engineered Human Vascular Networks During Deep Wound Healing

(2013) Donny Hanjaya-Putra et al.   Stem Cells Translational Medicine

Cell–matrix interactions regulate mesenchymal stem cell response to hydrostatic pressure

(2012) A.J. Steward et al.   Acta Biomaterialia

Chemical and Topographical Effects on Cell Differentiation and Matrix Elasticity in a Corneal Stromal Layer Model

(2012) Samantha L. Wilson et al.   ADVANCED FUNCTIONAL MATERIALS

Molecular mechanism of force induced stabilization of collagen against enzymatic breakdown

(2012) Shu-Wei Chang et al.   BIOMATERIALS

The influence of chitosan hydrogel on stem cell engraftment, survival and homing in the ischemic myocardial microenvironment

(2012) Zhiqiang Liu et al.   BIOMATERIALS

The alignment and fusion assembly of adipose-derived stem cells on mechanically patterned matrices

(2012) Yu Suk Choi et al.   BIOMATERIALS

Fully defined in situ cross-linkable alginate and hyaluronic acid hydrogels for myocardial tissue engineering

(2012) Julia Dahlmann et al.   BIOMATERIALS

LINC Complexes Form by Binding of Three KASH Peptides to Domain Interfaces of Trimeric SUN Proteins

(2012) Brian A. Sosa et al.   CELL

Adhesion in the stem cell niche: biological roles and regulation

(2012) S. Chen et al.   DEVELOPMENT

Strategies for developing decellularized corneal scaffolds

(2012) Amy P. Lynch et al.   EXPERIMENTAL EYE RESEARCH

Bioactive polymer scaffold for fabrication of vascularized engineering tissue

(2012) Irza Sukmana   JOURNAL OF ARTIFICIAL ORGANS

Nanofibrillar cellulose hydrogel promotes three-dimensional liver cell culture

(2012) Madhushree Bhattacharya et al.   JOURNAL OF CONTROLLED RELEASE

Biomimetic mineralization of acid polysaccharide-based hydrogels: towards porous 3-dimensional bone-like biocomposites

(2012) Chao Zhong et al.   JOURNAL OF MATERIALS CHEMISTRY

Cyclic tensile strain upon human mesenchymal stem cells in 2D and 3D culture differentially influences CCNL2, WDR61 and BAHCC1 gene expression levels

(2012) Sarah R. Rathbone et al.   Journal of the Mechanical Behavior of Biomedical Materials

Enzymatic Mineralization of Hydrogels for Bone Tissue Engineering by Incorporation of Alkaline Phosphatase

(2012) Timothy E. L. Douglas et al.   MACROMOLECULAR BIOSCIENCE

Mechanical properties andin vitrobehavior of nanofiber–hydrogel composites for tissue engineering applications

(2012) Dan Kai et al.   NANOTECHNOLOGY

Extracellular-matrix tethering regulates stem-cell fate

(2012) Britta Trappmann et al.   NATURE MATERIALS

Hydrogel crosslinking density regulates temporal contractility of human embryonic stem cell-derived cardiomyocytes in 3D cultures

(2012) Cindy Chung et al.   Soft Matter

Ex vivo expansion of limbal stem cells is affected by substrate properties

(2012) Roanne R. Jones et al.   Stem Cell Research

Substrate Stiffness Modulates Gene Expression and Phenotype in Neonatal Cardiomyocytes In Vitro

(2012) Giancarlo Forte et al.   TISSUE ENGINEERING PART A

The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration

(2012) Shyam B. Khatau et al.   Scientific Reports

Carbon Nanotube Reinforced Hybrid Microgels as Scaffold Materials for Cell Encapsulation

(2011) Su Ryon Shin et al.   ACS Nano

Tuning the dependency between stiffness and permeability of a cell encapsulating hydrogel with hydrophilic pendant chains

(2011) Chaenyung Cha et al.   Acta Biomaterialia

Three-Dimensional Spatial Patterning of Proteins in Hydrogels

(2011) Ryan G. Wylie et al.   BIOMACROMOLECULES

Highly Extensible, Tough, and Elastomeric Nanocomposite Hydrogels from Poly(ethylene glycol) and Hydroxyapatite Nanoparticles

(2011) Akhilesh K. Gaharwar et al.   BIOMACROMOLECULES

Enhanced MSC chondrogenesis following delivery of TGF-β3 from alginate microspheres within hyaluronic acid hydrogels in vitro and in vivo

(2011) Liming Bian et al.   BIOMATERIALS

Insights into interstitial flow, shear stress, and mass transport effects on ECM heterogeneity in bioreactor-cultivated engineered cartilage hydrogels

(2011) Tony Chen et al.   Biomechanics and Modeling in Mechanobiology

Viscoelastic properties and nanoscale structures of composite oligopeptide-polysaccharide hydrogels

(2011) Laura L. Hyland et al.   BIOPOLYMERS

A growth factor delivery system for chondrogenic induction of infrapatellar fat pad-derived stem cells in fibrin hydrogels

(2011) Mark Ahearne et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

A bioresponsive hydrogel tuned to chondrogenesis of human mesenchymal stem cells

(2011) Chelsea S. Bahney et al.   FASEB JOURNAL

Alterations of collagen-I, MMP-1 and TIMP-1 in the periodontal ligament of diabetic rats under mechanical stress

(2011) L. Zhang et al.   JOURNAL OF PERIODONTAL RESEARCH

Mechanical Load Induces a 100-Fold Increase in the Rate of Collagen Proteolysis by MMP-1

(2011) Arjun S. Adhikari et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The effect of cyclic hydrostatic pressure on the functional development of cartilaginous tissues engineered using bone marrow derived mesenchymal stem cells

(2011) E.G. Meyer et al.   Journal of the Mechanical Behavior of Biomedical Materials

Collagen gel three-dimensional matrices combined with adhesive proteins stimulate neuronal differentiation of mesenchymal stem cells

(2011) J. H. Lee et al.   Journal of the Royal Society Interface

Portable nanofiber meshes dictate cell orientation throughout three-dimensional hydrogels

(2011) Ying Yang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Dextran hydrogel scaffolds enhance angiogenic responses and promote complete skin regeneration during burn wound healing

(2011) G. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sustained release of VEGF from PLGA nanoparticles embedded thermo-sensitive hydrogel in full-thickness porcine bladder acellular matrix

(2011) Hongquan Geng et al.   Nanoscale Research Letters

Influence of cell-adhesive peptide ligands on poly(ethylene glycol) hydrogel physical, mechanical and transport properties

(2010) Silviya P. Zustiak et al.   Acta Biomaterialia

Interactions Between Nuclei and the Cytoskeleton Are Mediated by SUN-KASH Nuclear-Envelope Bridges

(2010) Daniel A. Starr et al.   Annual Review of Cell and Developmental Biology

Bioactive hydrogels made from step-growth derived PEG–peptide macromers

(2010) Jordan S. Miller et al.   BIOMATERIALS

Plastic compressed collagen as a biomimetic substrate for human limbal epithelial cell culture

(2010) Hannah J. Levis et al.   BIOMATERIALS

Heparin-based hydrogel as a matrix for encapsulation and cultivation of primary hepatocytes

(2010) Mihye Kim et al.   BIOMATERIALS

The effect of matrix characteristics on fibroblast proliferation in 3D gels

(2010) Katrin Bott et al.   BIOMATERIALS

Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2

(2010) J. Patterson et al.   BIOMATERIALS

Bioactive modification of poly(ethylene glycol) hydrogels for tissue engineering

(2010) Junmin Zhu   BIOMATERIALS

Towards a quantitative understanding of oxygen tension and cell density evolution in fibrin hydrogels

(2010) Jan Demol et al.   BIOMATERIALS

Compressed collagen gel as the scaffold for skin engineering

(2010) Kuikui Hu et al.   BIOMEDICAL MICRODEVICES

Influence of cell and collagen concentration on the cell–matrix mechanical relationship in a corneal stroma wound healing model

(2010) Mark Ahearne et al.   EXPERIMENTAL EYE RESEARCH

Molecular Mechanism of Type I Collagen Homotrimer Resistance to Mammalian Collagenases

(2010) Sejin Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evaluation of alginate hydrogels under in vivo–like bioreactor conditions for cartilage tissue engineering

(2010) Jasmina Stojkovska et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Kinetic studies of a composite carbon nanotube-hydrogel for tissue engineering by rheological methods

(2010) Fan Xie et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Dual growth factor-releasing nanoparticle/hydrogel system for cartilage tissue engineering

(2010) Sung Mook Lim et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Alignment hierarchies: engineering architecture from the nanometre to the micrometre scale

(2010) A. Kureshi et al.   Journal of the Royal Society Interface

An optical method to quantify the density of ligands for cell adhesion receptors in three-dimensional matrices

(2010) D. S. Tzeranis et al.   Journal of the Royal Society Interface

Alignment of Astrocytes Increases Neuronal Growth in Three-Dimensional Collagen Gels and Is Maintained Following Plastic Compression to Form a Spinal Cord Repair Conduit

(2010) Emma East et al.   TISSUE ENGINEERING PART A

Cyclic Tensile Culture Promotes Fibroblastic Differentiation of Marrow Stromal Cells Encapsulated in Poly(Ethylene Glycol)-Based Hydrogels

(2010) Derek M. Doroski et al.   TISSUE ENGINEERING PART A

A Collagen–Chitosan Hydrogel for Endothelial Differentiation and Angiogenesis

(2010) Chao Deng et al.   TISSUE ENGINEERING PART A

Ex Vivo Construction of an Artificial Ocular Surface by Combination of Corneal Limbal Epithelial Cells and a Compressed Collagen Scaffold Containing Keratocytes

(2010) Shengli Mi et al.   TISSUE ENGINEERING PART A

Matrix Deposition Modulates the Viscoelastic Shear Properties of Hydrogel-Based Cartilage Grafts

(2010) Leo Q. Wan et al.   TISSUE ENGINEERING PART A

Mineralization of Hydrogels for Bone Regeneration

(2010) Katerina Gkioni et al.   TISSUE ENGINEERING PART B-REVIEWS

Carbon nanofibers and carbon nanotubes in regenerative medicine

(2009) Phong A. Tran et al.   ADVANCED DRUG DELIVERY REVIEWS

The influence of hydrogel modulus on the proliferation and differentiation of encapsulated neural stem cells

(2009) Akhilesh Banerjee et al.   BIOMATERIALS

An alginate hydrogel matrix for the localised delivery of a fibroblast/keratinocyte co-culture

(2009) Nicola C. Hunt et al.   Biotechnology Journal

Mechanical force enhances MMP-2 activation via p38 signaling pathway in human retinal pigment epithelial cells

(2009) Xu Hou et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Functional properties of cartilaginous tissues engineered from infrapatellar fat pad-derived mesenchymal stem cells

(2009) Conor Timothy Buckley et al.   JOURNAL OF BIOMECHANICS

Performance of new gellan gum hydrogels combined with human articular chondrocytes for cartilage regeneration when subcutaneously implanted in nude mice

(2009) J. T. Oliveira et al.   Journal of Tissue Engineering and Regenerative Medicine

Spatially controlled hydrogel mechanics to modulate stem cell interactions

(2009) Ross A. Marklein et al.   Soft Matter

Hydrostatic Pressure in Articular Cartilage Tissue Engineering: From Chondrocytes to Tissue Regeneration

(2009) Benjamin D. Elder et al.   TISSUE ENGINEERING PART B-REVIEWS

Online Monitoring of the Mechanical Behavior of Collagen Hydrogels: Influence of Corneal Fibroblasts on Elastic Modulus

(2009) Mark Ahearne et al.   TISSUE ENGINEERING PART C-METHODS

Guiding cell migration in 3D: A collagen matrix with graded directional stiffness

(2009) Ektoras Hadjipanayi et al.   CELL MOTILITY AND THE CYTOSKELETON

Synthesis and viscoelastic characterization of novel hydrogels generated via photopolymerization of 1,2-epoxy-5-hexene modified poly(vinyl alcohol) for use in tissue replacement

(2008) Rebecca A. Bader   Acta Biomaterialia

Hydrogel based on interpenetrating polymer networks of dextran and gelatin for vascular tissue engineering

(2008) Yunxiao Liu et al.   BIOMATERIALS

Substrate Modulus Directs Neural Stem Cell Behavior

(2008) Krishanu Saha et al.   BIOPHYSICAL JOURNAL

Mechanical characterization of biomimetic membranes by micro-shaft poking

(2008) M. Ahearne et al.   Journal of the Royal Society Interface

Fibrin gels and their clinical and bioengineering applications

(2008) P. A Janmey et al.   Journal of the Royal Society Interface

Online monitoring of collagen fibre alignment in tissue-engineered tendon by PSOCT

(2008) Mark Ahearne et al.   Journal of Tissue Engineering and Regenerative Medicine

Close dependence of fibroblast proliferation on collagen scaffold matrix stiffness

(2008) E. Hadjipanayi et al.   Journal of Tissue Engineering and Regenerative Medicine

A chemical approach to stem-cell biology and regenerative medicine

(2008) Yue Xu et al.   NATURE

The coming acceleration of global population ageing

(2008) Wolfgang Lutz et al.   NATURE

In situ collagen assembly for integrating microfabricated three-dimensional cell-seeded matrices

(2008) Brian M. Gillette et al.   NATURE MATERIALS

Filopodia: molecular architecture and cellular functions

(2008) Pieta K. Mattila et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Fibrin: A Versatile Scaffold for Tissue Engineering Applications

(2008) Tamer A.E. Ahmed et al.   TISSUE ENGINEERING PART B-REVIEWS

Nanomechanics of collagen fibrils under varying cross-link densities: Atomistic and continuum studies

(2007) Markus J. Buehler   Journal of the Mechanical Behavior of Biomedical Materials