Controlling matrix stiffness and topography for the study of tumor cell migration

Nanotopography as modulator of human mesenchymal stem cell function

(2012) Karina Kulangara et al.   BIOMATERIALS

Biophysical control of invasive tumor cell behavior by extracellular matrix microarchitecture

(2012) Shawn P. Carey et al.   BIOMATERIALS

Epithelial cell guidance by self-generated EGF gradients

(2012) Cally Scherber et al.   Integrative Biology

Extracellular-matrix tethering regulates stem-cell fate

(2012) Britta Trappmann et al.   NATURE MATERIALS

Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK

(2012) A-M Baker et al.   ONCOGENE

Chemotaxis of Cell Populations through Confined Spaces at Single-Cell Resolution

(2012) ZiQiu Tong et al.   PLoS One

Real-Time Visualization and Quantitation of Vascular Permeability In Vivo: Implications for Drug Delivery

(2012) Desmond B. S. Pink et al.   PLoS One

Cellular Traction Stresses Increase with Increasing Metastatic Potential

(2012) Casey M. Kraning-Rush et al.   PLoS One

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

(2011) Matthew W. Conklin et al.   AMERICAN JOURNAL OF PATHOLOGY

Matrix metalloproteinases in tumorigenesis: an evolving paradigm

(2011) Hui Hua et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

In situ force mapping of mammary gland transformation

(2011) Jose I. Lopez et al.   Integrative Biology

Fabrication of Substrates with Defined Mechanical Properties and Topographical Features for the Study of Cell Migration

(2011) Jonathan M. Charest et al.   MACROMOLECULAR BIOSCIENCE

Microfabricated Physical Spatial Gradients for Investigating Cell Migration and Invasion Dynamics

(2011) Michael Mak et al.   PLoS One

Probing the invasiveness of prostate cancer cells in a 3D microfabricated landscape

(2011) L. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-Related Intimal Stiffening Enhances Endothelial Permeability and Leukocyte Transmigration

(2011) J. Huynh et al.   Science Translational Medicine

Substrate stiffening promotes endothelial monolayer disruption through enhanced physical forces

(2010) Ramaswamy Krishnan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Effects of Morphology vs. Cell–Cell Interactions on Endothelial Cell Stiffness

(2010) Kimberly M. Stroka et al.   Cellular and Molecular Bioengineering

Substrate Stiffness and Cell Area Predict Cellular Traction Stresses in Single Cells and Cells in Contact

(2010) Joseph P. Califano et al.   Cellular and Molecular Bioengineering

Effect of substrate stiffness and PDGF on the behavior of vascular smooth muscle cells: Implications for atherosclerosis

(2010) Xin Q. Brown et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Neutrophil adhesion and chemotaxis depend on substrate mechanics

(2010) Risat A Jannat et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Impact of Tumor Cell Cytoskeleton Organization on Invasiveness and Migration: A Microchannel-Based Approach

(2010) Claudio G. Rolli et al.   PLoS One

Matrix Rigidity Regulates Cancer Cell Growth and Cellular Phenotype

(2010) Robert W. Tilghman et al.   PLoS One

Different sensitivity of human endothelial cells, smooth muscle cells and fibroblasts to topography in the nano–micro range

(2009) Sarah A. Biela et al.   Acta Biomaterialia

Engineering Substrate Topography at the Micro- and Nanoscale to Control Cell Function

(2009) Christopher J. Bettinger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Vascular Smooth Muscle Cell Durotaxis Depends on Substrate Stiffness Gradient Strength

(2009) Brett C. Isenberg et al.   BIOPHYSICAL JOURNAL

The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells

(2009) T. A. Ulrich et al.   CANCER RESEARCH

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Cell-Cycle Control by Physiological Matrix Elasticity and In Vivo Tissue Stiffening

(2009) Eric A. Klein et al.   CURRENT BIOLOGY

Spontaneous migration of cancer cells under conditions of mechanical confinement

(2009) Daniel Irimia et al.   Integrative Biology

Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited

(2009) Farideh Sabeh et al.   JOURNAL OF CELL BIOLOGY

One-dimensional topography underlies three-dimensional fibrillar cell migration

(2009) Andrew D. Doyle et al.   JOURNAL OF CELL BIOLOGY

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

Differential Matrix Rigidity Response in Breast Cancer Cell Lines Correlates with the Tissue Tropism

(2009) Ana Kostic et al.   PLoS One

Stem cell fate dictated solely by altered nanotube dimension

(2009) S. Oh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substrate topography shapes cell function

(2009) Karina Kulangara et al.   Soft Matter

Contact Guidance Mediated Three-Dimensional Cell Migration is Regulated by Rho/ROCK-Dependent Matrix Reorganization

(2008) Paolo P. Provenzano et al.   BIOPHYSICAL JOURNAL

Microarchitecture of Three-Dimensional Scaffolds Influences Cell Migration Behavior via Junction Interactions

(2008) Brendan A.C. Harley et al.   BIOPHYSICAL JOURNAL

Collagen density promotes mammary tumor initiation and progression

(2008) Paolo P Provenzano et al.   BMC Medicine

A Balance of Substrate Mechanics and Matrix Chemistry Regulates Endothelial Cell Network Assembly

(2008) Joseph P. Califano et al.   Cellular and Molecular Bioengineering

Extracellular Matrix Rigidity Promotes Invadopodia Activity

(2008) Nelson R. Alexander et al.   CURRENT BIOLOGY

Structural parameters of polyacrylamide hydrogels obtained by the Equilibrium Swelling Theory

(2008) Luiz M. Lira et al.   EUROPEAN POLYMER JOURNAL

The role of matrix stiffness in regulating cell behavior

(2008) Rebecca G. Wells   HEPATOLOGY

Environmental sensing through focal adhesions

(2008) Benjamin Geiger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY