Article
Chemistry, Multidisciplinary
Matthew P. Heaney, Daniel K. Unruh, Tomce Runcevski
Summary: Beta-naphthol reds are widely used pigments with significant historical, commercial, and cultural importance. This research focuses on the structural characterization of two prominent beta-naphthol reds, pigment red 40 (PR40) and pigment red 4 (PR4). The study confirms that both pigments exist as keto/hydrazones in the solid state, and suggests that they should not be mistakenly labeled as azo pigments. The research also investigates the lightfastness of the pigments, finding that while they remain stable in the solid state, degradation occurs when exposed to UV radiation in solution.
CRYSTAL GROWTH & DESIGN
(2022)
Article
Chemistry, Multidisciplinary
Ming-Ho Liu, Zhe Zhang, Yu-Chi Yang, Yang-Hsiang Chan
Summary: This study presents semiconductor polymers with emission characteristics in the NIR-IIa window, which show potential for high-resolution, noninvasive brain imaging in live mice and offer a platform for future design of NIR-IIa or even NIR-IIb emitting Pdots.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Polymer Science
Yuhang Li, Yunhao Luan, Wanyi Liu, Cong Wang, Hui Cao, Pengtao Liu
Summary: This study reports an improved method to prepare cellulose nanofibrils/polyvinyl alcohol (CNF/PVA) porous composite hydrogel and utilize it to support metal nanoparticles in order to enhance the catalytic degradation of dyes. The hydrogel adsorbs silver ions on its surface and reduces them to silver nanoparticles using an in situ reduction method, leading to efficient discoloration of cationic dyes. The hydrogel exhibits fast recovery and reusability, and holds great potential in water resources protection and catalytic applications.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Polymer Science
Martina Staffova, Frantisek Kucera, Jiri Tochacek, Petr Dzik, Frantisek Ondreas, Josef Jancar
Summary: The study delved into the dynamic color and phase change of selected thermochromic systems, incorporating them into polyurethane textile coatings. It explored the colorimetric properties of three commercial reversible leuco dyes-based thermochromic pigments and improved color stability in polyurethane coatings through UV absorbers, offering new possibilities in the field of smart textiles.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Environmental Sciences
Jannatun Zia, Shahzada Misbah Farhat, Elham S. Aazam, Ufana Riaz
Summary: Catalytic degradation based on microwave irradiation shows efficient degradation of organic pollutants. PNA/CaFe(2)O(4) nanohybrids exhibit higher degradation efficiency compared to PNA and pure CaFe2O4, with reactive species responsible for degradation confirmed by scavenger studies. Recyclability tests demonstrate the high reusability of the catalyst even after three cycles.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Polymer Science
Ahmed M. Elgamal, Nahed A. Abd El-Ghany, Gamal R. Saad
Summary: This study investigated the removal efficiency of anionic acid dye and hexavalent chromium using CMX-g-P(4VP) as an adsorbent. The results showed that the optimal pH for adsorption was 2.5. The adsorbent exhibited high adsorption capacities for both contaminants, and could be efficiently reused for multiple cycles.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Polymer Science
Victor H. Pino-Ramos, Emilio Bucio, David Diaz
Summary: The study reports an eco-friendly method for polypropylene degradation using catalytic bismuth nanoparticles assisted by ionizing radiation, achieving high oxidation efficiencies even at low catalyst load and irradiation dose. Various analytical techniques were used to confirm the successful oxidation of polypropylene and identify the main degradation products.
POLYMER DEGRADATION AND STABILITY
(2021)
Article
Engineering, Environmental
Xia Xu, Ke Jia, Shifei Chen, Daning Lang, Chao Yang, Lu Wang, Ronglan Wu, Wei Wang, Jide Wang
Summary: A simple one-pot method for synthesizing Cu2O/Cu nanoparticles was developed and characterized in this study. The nanoparticles showed excellent catalytic activity for the degradation of phenolics and dyes, exhibiting the fastest degradation rates compared to previously reported cuprous catalysts.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Polymer Science
Boon-Leong Lim, Desmond Teck-Chye Ang
Summary: This study focuses on the importance of developing coating additives using sustainable materials and presents a method to produce fatty acid-based polymeric dispersant. The results show that this dispersant can efficiently disperse pigments and produce coatings with good optical properties and gloss retention.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Polymer Science
Jiayan Shi, Chunhua Wei, Mengyu Deng, Lei Liang, Yanqing Tian
Summary: Pressure-sensitive paints (PSPs) are crucial for aerodynamics research. To enhance the pressure sensitivity and adhesion of PSPs, a series of fluorine-containing copolymers were synthesized and studied. These PSPs were constructed with different fluorine ratios, and PSP (F-0.33) with a trifluoroethyl methacrylate (TFEM) molar ratio of 33% exhibited excellent adhesion to the surface of an aircraft model. F-0.33 showed high oxygen sensitivity, reasonable response time, high pressure sensitivity, and low temperature response. It was further tested on a delta wing in a wind tunnel and showed similar pressure data to the traditional method using open pressure holes, indicating the potential application of these PSPs.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Polymer Science
Massimo Calovi, Francesca Russo, Stefano Rossi
Summary: This study evaluates the aesthetical performances of thermochromic coatings for outdoor applications, focusing on their efficiency in different primers and the protective role of a transparent topcoat. Results show that the double-layer coating exhibits remarkable color-changing behavior even when exposed to aggressive environments, with the transparent topcoat maintaining the integrity of the cataphoretic primer.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Environmental Sciences
Sandhya Mishra, Sushma Kumari, Prashant Kumar, Sujoy Kumar Samanta
Summary: Microwave catalysis is highly lucrative due to its ability for prompt mineralization and superior efficiency. Strontium hexaferrite 2D sheets have been explored as effective catalysts for the degradation of organic dyes and antibiotics. The research suggests the emergence of microwave catalysis as a new technology.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Polymer Science
Dong Feng, Pengju Liu
Summary: A microwave-assisted foaming and selective sintering approach was proposed for rapid fabrication of robust PEI bead foams, with important parameters being MW irradiation power and time. Graphene nanoplatelets were used as MW absorbent to promote inter-bead bonding strength, successfully fabricating high-performance foamed parts.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Review
Engineering, Environmental
J. Ambigadevi, P. Senthil Kumar, Dai-Viet N. Vo, S. Hari Haran, T. N. Srinivasa Raghavan
Summary: The textile industry plays a significant role in the Indian economy, however, the synthetic dyes used in this industry pose a serious threat to the environment. Heterogeneous photocatalysis using semiconductor-based nanoparticles has emerged as an effective solution for treating textile effluent and various nanostructures have shown promising results in degrading harmful pollutants.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Spectroscopy
Yacine Oubelkacem, Taibi Lamhasni, Abdelmajid El Bakkali, Saadia Ait Lyazidi, Mustapha Haddad, Abdelouahed Ben-Ncer
Summary: Two famous ancient parchments from the IXth century in the Islamic world were analyzed using various techniques to identify writing support materials, ink components, degradation phenomena, and corrosion prevention methods, as well as the use of different coloring materials.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Review
Chemistry, Multidisciplinary
Ufana Riaz, Neetika Singh, Sayma Banoo
Summary: This short review article discusses the computational studies conducted on conducting polymers such as polyacetylene, polyaniline, polypyrrole, and others to predict their electronic, optoelectronic, and structural properties. The article elaborates on the studies using semi-empirical methods and density functional theory (DFT). It also highlights the latest research on sensing applications, which can be beneficial for researchers in this field. The conclusion section analyzes the significance of theoretical parameters in predicting the properties of conducting polymers for designing electronic, electrochemical, and sensing devices.
NEW JOURNAL OF CHEMISTRY
(2022)
Review
Polymer Science
Neetika Singh, Ufana Riaz
Summary: Conducting polymers have been extensively studied due to their unique electrical, optical, and mechanical properties, as well as their ease of synthesis and high environmental stability. This review discusses the fundamental properties of conducting polymers, various methods of polymerization, and the synergistic effects observed in these polymers. Current applications in energy, medical diagnostics, and sensing devices are also discussed.
Review
Polymer Science
Ufana Riaz, Neetika Singh, Fathimath Rashnas Srambikal, Sumbul Fatima
Summary: This review focuses on the recent advancements in conducting polymeric hydrogels based on polyaniline (PANT) and polypyrrole (PPy). The synthesis strategies and common characterization techniques for PANI- and PPy-based hydrogels are discussed. The review also covers the current literature on biomedical and electrochemical applications of these materials.
Article
Chemistry, Multidisciplinary
Anurakshee Verma, Romana Parveen, Tooba Naz Shamsi, Azmat Ali Khan, Sadaf Fatima, Elham S. Aazam, Ufana Riaz
Summary: In this study, intercalation and in-situ polymerization of POPD within MMT were successfully achieved using sonochemical technique. The antimicrobial activity of MMT/POPD nanocomposites against four bacterial strains was examined, and the results indicated that the nanocomposites showed potential as antibacterial agents.
Article
Chemistry, Physical
Aleena Mir, Amit Kumar, Ufana Riaz
Summary: In this study, sodium alginate-based composite hydrogels using polyaniline (PANI), poly(o-phenylenediamine) (POPD), poly(1-naphthylamine) (PNA), and poly(vinylidene fluoride) (PVDF) were synthesized and characterized. The hydrogels were investigated for their spectral, morphological, and rheological properties. Metformin hydrochloride (MFH) was used as a model drug, and the release profiles were studied using intestinal fluid pH of 7.4. The incorporation of conducting polymers as crosslinking agents significantly affected the release behavior, which could be used to optimize and control the release of metformin hydrochloride.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Polymer Science
Jannatun Zia, Mohd Riyazuddin, Shaila Jackson, Darlene K. Taylor, Ufana Riaz
Summary: The synthesis of nanocomposites of beta-cyclodextrin (beta-CD) with polyaniline (PANI) and polypyrrole (PPy) to design core-shell nanocomposites was reported in this study. The spectral, morphological, and thermal characteristics of the synthesized nanocomposites were investigated. The incorporation of PANI and PPy in beta-CD was confirmed by IR spectra, while UV-visible spectra confirmed the polaronic state of conducting polymers in the nanocomposites. SEM analysis revealed the core-shell like morphology of the nanocomposites. In vitro drug release studies using ciprofloxacin (CIP) showed sustained release behavior of the nanocomposites, indicating their potential as effective antibiotic drug delivery vehicles.
Article
Materials Science, Multidisciplinary
Ufana Riaz, Nuzhat Nabi, Faith R. Nwanze, Fei Yan
Summary: This study for the first time reports the modification of aniline with alanine using ultrasound-assisted polymerization. The formation of Ala-incorporated polyaniline (PANI) was confirmed by various analyses. The binding affinity of Ala/PANI towards BSA and HSA was found to be good, with hydrogen bonding and Van der Waal's forces playing a significant role.
Article
Chemistry, Physical
Ishfaq Ahmad Rather, Ufana Riaz, Rashid Ali
Summary: UV-vis spectroscopy and TD-DFT calculations were used to investigate the anion binding of meso-substituted one-walled phthalimide-based calix[4]pyrrole (m-PC4P, 6) in acetonitrile. The results showed that m-PC4P (6) exhibited higher anion binding affinities compared to the parent C4P system, possibly due to additional weak CH-anion interactions besides four NH-hydrogen bonds of the C4P framework. The binding affinity decreased with the increase in halide size from fluoride to iodide, and m-PC4P (6) showed better binding with nitrate anion compared to simple C4P (1).
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Multidisciplinary Sciences
Ufana Riaz, Shayista Gaffar, Kristen Hauser, Fei Yan
Summary: This study presents a facile synthesis of CuFe2O4 nanoparticles and their formulation as nanohybrids with polythiophene (PTh). The structural and morphological properties were characterized using FT-IR, XRD, SEM-EDS, and UV-Vis spectroscopy. The nanohybrids exhibited a decrease in band gap with increasing PTh loading. The nanohybrids were applied as photocatalysts for the degradation of diphenyl urea and polyethylene under visible light and microwave irradiation, with promising catalytic efficiency observed.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Physical
Shayista Gaffar, Aleena Mir, Amit Kumar, Javed Alam, Ufana Riaz
Summary: This study reports for the first time the microwave-assisted catalytic degradation of isoniazid drug using organic-inorganic hybrids of PTh decorated ZnFe2O4 nanoparticles. The nanohybrids demonstrated high efficiency in degrading the drug within a short period of time, and a tentative mechanism of degradation was proposed.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Multidisciplinary
Aaliyah Farooq, Javed Alam, Ufana Riaz
Summary: This study reports the use of Polypyrrole/Polythiophene Co-Oligomers as photocatalysts for the degradation of Bisphenol A. The results show that the organic photocatalysts achieved efficient degradation within 120 minutes, even for high concentrations of Bisphenol A.
Article
Chemistry, Physical
Ufana Riaz, Syed Marghoob Ashraf
Summary: This study reports the synthesis of a dye-incorporated o-phenylenediamine oligomer and analyzes its structure and electronic transitions. The results demonstrate that the dye-modified oligomer exhibits higher fluorescence intensity and can be used for near infra-red imaging. Density functional theory (DFT) studies predict the theoretical properties of the oligomer and suggest its potential application as a drug sensor.
ACS PHYSICAL CHEMISTRY AU
(2023)
Article
Chemistry, Multidisciplinary
Ufana Riaz, Aaliyah Farooq, Nuzhat Nabi, Faith R. Nwanze, Fei Yan
Summary: This study reports the synthesis and characterization of water-dispersible polypyrrole (WD-PPy) and polythiophene (WD-PTh) copolymers in different weight ratios using experimental and theoretical techniques. Spectroscopic characterization of the copolymers was conducted using experimental C-13-NMR, FTIR, and UV-visible studies, as well as theoretical FTIR and UV-visible studies. Furthermore, biophysical interaction studies with bovine serum albumin (BSA) and human serum albumin (HSA) were performed, revealing strong binding with potential applications in designing inhibitors and biosensors.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Polymer Science
Aaliyah Farooq, Nuzhat Nabi, Javed Alam, Ufana Riaz
Summary: Water-soluble polyfuran and polythiophene co-oligomers were synthesized and their biophysical interactions with bovine serum albumin and human serum albumin were studied. The interactions were found to be higher with human serum albumin, and were mediated through hydrogen bonding and pi-alkyl interaction. These co-oligomers showed high binding affinity towards human serum albumin, suggesting their potential use in protein sensors.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2023)
Article
Environmental Sciences
Shayista Gaffar, Amit Kumar, Javed Alam, Ufana Riaz
Summary: In this study, CuFe2O4 and CuFe2O4/polyaniline (PANI) nanohybrids were used as photocatalysts for the degradation of TC-HCl. The nanohybrids showed superior photocatalytic performance compared to pristine CuFe2O4, with a maximum degradation rate of 86%. The degraded fragments were analyzed and a tentative degradation mechanism was proposed.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Wafa A. Bawazir, Maymoona A. Al-Mahmood, Rawan S. Almalki, Ghadi F. Alofi, Raghad S. Alharbi, Zoya Zaheer
Summary: This study investigates the interaction between sulfathiazole and three types of surfactants using UV-visible spectroscopy and conductivity measurements. The results show that the critical micelle concentration of cationic and anionic surfactants decreases with increasing sulfathiazole concentration, while the interaction with non-ionic surfactant is weak.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Musaad K. Aleid, Khalid N. Alharbi, Mona A. Aljufareen, Areej S. Aloliwi, Alhanouf K. Almutairi, Rahaf S. Alsaif, Nada K. Alshayeb, Mohammed S. Almoiqli
Summary: This study assessed the levels of trihalomethane compounds in the water network of Riyadh city and identified the factors influencing their formation. The concentrations of trihalomethane compounds were within the permissible limits, indicating the water's safety for human consumption. The presence of bromide ions, organic carbon, free chlorine, and pH values were found to affect trihalomethane formation.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Said Arhzaf, Jamal Houssaini, Mohammed Naciri Bennani, Marwa Alaqarbeh, Mohammed Bouachrine
Summary: The study shows that Mg-Al hydrotalcite catalysts intercalated with acetate and carbonate anions exhibit superior catalytic activity in the aldol condensation reaction between furfural and acetone. The optimal reaction conditions are at 90 degrees C for 2 hours, achieving conversion rates of over 98% with high selectivity towards F2A for the acetate catalyst.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Uyen-Chi Nguyen Le, Ngoc Xuan Dat Mai, Kieu-Minh Le, Hoang Anh Vu, Huynh-Nhu Thi Tran, Tan Le Hoang Doan
Summary: This study aimed to enhance the bioavailability of rosmarinic acid, a bioactive compound with high anticancer activity, by encapsulating it in tetrasulfide-based porous organosilica nanoparticles. The synthesized nanoparticles were small in size and had a high surface area and an average pore diameter. The nanoparticles showed effective accumulation in cancer cells without toxicity to normal cells. Treatment with rosmarinic acid-containing nanoparticles resulted in significant cell death in cancer cells. Overall, these findings suggest that the synthesized nanoparticles can enhance the pharmacological effects of rosmarinic acid.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Jiamin Qi, Hengxi Zhu, Tianyu Yang, Xingyuan Wang, Zixuan Wang, Xiaoli Lei, Bin Li, Wenmin Qian
Summary: This study synthesized a novel iron-biochar adsorbent using the iron content in red mud to remove heavy metals from wastewater. The adsorbent showed excellent removal efficiency and sustainability. This method addresses both industrial waste recovery and heavy metal adsorption issues.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Bo Yi, Li Zhang, Haiyang Zhou
Summary: Plasma protein binding plays a crucial role in the pharmacokinetics and pharmacodynamics of therapeutic bioactive materials. In this study, the interaction of nordentatin, a member of coumarins, with human alpha-1 acid glycoprotein (AGP) was investigated, and the anticancer potency of nordentatin against human colorectal cancer cells was evaluated. The results showed that nordentatin binds to AGP through a static quenching mechanism and exhibits inhibitory effects on the growth of HCT-116 cells by increasing intracellular ROS and [Ca2+] levels and triggering apoptosis-related gene overexpression. Therefore, nordentatin could be a promising plant-based therapy for colorectal cancer.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Qiming Pang, Cui Wang, Bangtao Li, Suli Zhang, Jiaoyang Li, Shuo Gu, Xueyu Shi
Summary: This study evaluated the effects of resveratrol loaded in copolymer nanoparticles on cerebral ischemia/reperfusion (I/R) injury in rats. The results showed that RES.CP.NPs could have neuroprotective effects through their antioxidant and anti-inflammatory activities, leading to improved neurological disability scores and decreased oxidative stress levels.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Maryam Rachmawati Sumitra, Lung-Ching Chen, Wei-Chen Tsai, Muhamad Ansar, Bashir Lawal, Ntlotlang Mokgautsi, Jih-Hwa Guh, Alexander T. H. Wu, Hsu-Shan Huang
Summary: Tetraheterocyclic compounds derived from natural sources and contemporary pharmaceuticals have shown promise as multitarget therapeutic agents. In this study, a series of synthesized compounds were evaluated for their potential in breast cancer treatment. Compounds 18 and 20 demonstrated significant antiproliferative activity against breast cancer cell lines and their mode of action was revealed through molecular docking simulations.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Mohammad Khosravani, Mohsen Dehghani Ghanatghestani, Farid Moeinpour, Hossein Parvaresh
Summary: The aim of removing Pb(II) from water is to minimize the potential harm posed by toxic metals to both human health and the environment. A covalent organic framework adsorbent called TFPOTDB-SO3H was developed with excellent properties such as high repeatability, selectivity, and easy solid-liquid separation. The adsorbent showed impressive capability of adsorbing Pb(II) and effective removal of it from a solution with various ions, suggesting its potential for effectively adsorbing and removing Pb(II) heavy metal ions from wastewater.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Ashraf H. Farha, Mohamed S. Shams, Hasna A. Alali, Zakia H. Alhashem, Shehab A. Mansour, Shrouq H. Aleithan, Ragab A. Elsad
Summary: The current study examines the dielectric and thermal properties of transformer oil incorporated with Mn0.5 Zn0.5 Fe2O4 nanoparticles. The results show that the addition of Mn-Zn ferrite NPs improves the dielectric constant, dissipation factor, AC breakdown voltage, and convective heat transfer of the nanofluid.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Limin Hou, Zongpei Jiang, Minqi Ye, Xueyan Sun, Kexin Liu, Yifan Zhu, Xiaoyu Wang, Liangzhu Chen, Ruiheng Gu, Binghu Fang
Summary: The excessive accumulation of antibiotic residue in animal-derived foods poses a threat to health. Therefore, it is necessary to establish a rapid, simple, effective, safe, and highly sensitive method for detecting lincomycin residues. By using a pre-column derivatization method on high-performance liquid chromatography equipped with ultraviolet, the UV absorption of lincomycin is improved, allowing for detection and quantification.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Kun Tang, Xin-Xin Wang, Jin-Jin Zhao, Ning Ren, Jian-Jun Zhang
Summary: This study reports the synthesis, crystal structures, and thermal degradation properties of three new rare earth coordination compounds. Compounds 1-3 exhibit binuclear structures which can form chain-like structures via hydrogen bonding. Compound 2 shows potential application value in the orange-red luminescence region.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Seoyoun Yang, Eunbi Yu, See-Hyoung Park, Sae Woong Oh, Kitae Kwon, Su Bin Han, Soo Hyun Kang, Jung Hyun Lee, Heejun Ha, Minkyung Song, Jae Youl Cho, Jongsung Lee
Summary: This study investigated the effects of blue light on the hypodermis and found that it has antiadipogenic properties by reducing lipid accumulation and downregulating the expression of adipogenic genes. Blue light also increased the phosphorylation of PPAR gamma and TRPV1, suggesting its anti-adipogenic effect through these signaling pathways.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Abdul Nasir, Abdul Waheed Khan, Hamid Rafiq Khattak, Abdus Samad, Sami Ullah, Haroon Khan, Muhammad Faheem, Qian Bai
Summary: This study evaluated the effects of isoxazolone derivatives on cisplatin-induced neuropathy in a rat model. The results showed that isoxazolone derivatives effectively reversed mechanical allodynia, similar to the known therapeutic agent pregabalin. Molecular docking analysis indicated that isoxazolone derivatives have strong binding affinity for relevant receptors and potential inhibitory activity against relevant signaling pathways. This study has innovative implications for the treatment of cisplatin-induced neuropathic pain.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Shahid Wahab, Haroon Muhammad Ali, Maham Khan, Tariq Khan, Chandran Krishnaraj, Soon-Il Yun
Summary: In this study, we synthesized chitosan nanoparticles, silver nanoparticles, and chitosan/silver nanocomposites using aqueous ginger extract as a green approach. These nanomaterials showed significant antibacterial properties and low toxicity. Furthermore, the nanomaterials conjugated with tobramycin demonstrated enhanced antibacterial efficacy and exhibited interactions with Pseudomonas aeruginosa.
ARABIAN JOURNAL OF CHEMISTRY
(2024)