FOXD1-dependent MICU1 expression regulates mitochondrial activity and cell differentiation

Advanced maturation of human cardiac tissue grown from pluripotent stem cells

(2018) Kacey Ronaldson-Bouchard et al.   NATURE

Mitochondrial Ca 2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity

(2017) Zhiwei Dong et al.   MOLECULAR CELL

MICU2 Restricts Spatial Crosstalk between InsP 3 R and MCU Channels by Regulating Threshold and Gain of MICU1-Mediated Inhibition and Activation of MCU

(2017) Riley Payne et al.   Cell Reports

Hepatocyte-like cells derived from induced pluripotent stem cells

(2016) Namita Roy-Chowdhury et al.   Hepatology International

Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells

(2016) Nathan J Palpant et al.   Nature Protocols

MICU1 regulation of mitochondrial Ca2+ uptake dictates survival and tissue regeneration

(2016) Anil Noronha Antony et al.   Nature Communications

MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload

(2016) Julia C. Liu et al.   Cell Reports

MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics

(2016) Dhanendra Tomar et al.   Cell Reports

EMRE Is a Matrix Ca 2+ Sensor that Governs Gatekeeping of the Mitochondrial Ca 2+ Uniporter

(2016) Horia Vais et al.   Cell Reports

MCUR1, CCDC90A, Is a Regulator of the Mitochondrial Calcium Uniporter

(2015) Horia Vais et al.   Cell Metabolism

Generation of iPSCs as a Pooled Culture Using Magnetic Activated Cell Sorting of Newly Reprogrammed Cells

(2015) Wenli Yang et al.   PLoS One

Transcriptional Landscape of Cardiomyocyte Maturation

(2015) Hideki Uosaki et al.   Cell Reports

Regulation of the mitochondrial Ca2+ uniporter by MICU1 and MICU2

(2014) J. Kevin Foskett et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Engineering Adolescence

(2014) Xiulan Yang et al.   CIRCULATION RESEARCH

MICU1 and MICU2 play nonredundant roles in the regulation of the mitochondrial calcium uniporter

(2014) K. J. Kamer et al.   EMBO REPORTS

LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation

(2014) Patrick J. Doonan et al.   FASEB JOURNAL

SLC25A23 augments mitochondrial Ca2+ uptake, interacts with MCU, and induces oxidative stress–mediated cell death

(2014) Nicholas E. Hoffman et al.   MOLECULAR BIOLOGY OF THE CELL

MICU1 and MICU2 Finely Tune the Mitochondrial Ca2+ Uniporter by Exerting Opposite Effects on MCU Activity

(2014) Maria Patron et al.   MOLECULAR CELL

Foxd1 is a mediator and indicator of the cell reprogramming process

(2014) Makito Koga et al.   Nature Communications

MICU1 Controls Both the Threshold and Cooperative Activation of the Mitochondrial Ca2+ Uniporter

(2013) György Csordás et al.   Cell Metabolism

The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter

(2013) Xin Pan et al.   NATURE CELL BIOLOGY

Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling

(2013) Clare V Logan et al.   NATURE GENETICS

MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling

(2013) Molly Plovanich et al.   PLoS One

Mitochondrial calcium uptake

(2013) G. S. B. Williams et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EMRE Is an Essential Component of the Mitochondrial Calcium Uniporter Complex

(2013) Y. Sancak et al.   SCIENCE

MICU1 Motifs Define Mitochondrial Calcium Uniporter Binding and Activity

(2013) Nicholas E. Hoffman et al.   Cell Reports

MCU encodes the pore conducting mitochondrial calcium currents

(2013) Dipayan Chaudhuri et al.   eLife

Upregulation of the mitochondrial Lon Protease allows adaptation to acute oxidative stress but dysregulation is associated with chronic stress, disease, and aging

(2013) Jenny K. Ngo et al.   Redox Biology

MICU1 Is an Essential Gatekeeper for MCU-Mediated Mitochondrial Ca2+ Uptake that Regulates Cell Survival

(2012) Karthik Mallilankaraman et al.   CELL

Epithelial-to-Mesenchymal and Endothelial-to-Mesenchymal Transition

(2012) Jason C. Kovacic et al.   CIRCULATION

MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism

(2012) Karthik Mallilankaraman et al.   NATURE CELL BIOLOGY

The PKB/FOXO switch in aging and cancer

(2011) David E.A. Kloet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization

(2011) S. Goossens et al.   BLOOD

FoxO family members in cancer

(2011) Yuqing Zhang et al.   CANCER BIOLOGY & THERAPY

The Permeability Transition Pore Controls Cardiac Mitochondrial Maturation and Myocyte Differentiation

(2011) Jennifer R. Hom et al.   DEVELOPMENTAL CELL

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

(2011) Joshua M. Baughman et al.   NATURE

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

(2011) Diego De Stefani et al.   NATURE

Temperature-dependent STIM1 activation induces Ca2+ influx and modulates gene expression

(2011) Bailong Xiao et al.   Nature Chemical Biology

Sensing cellular stress through STIM proteins

(2011) Jonathan Soboloff et al.   Nature Chemical Biology

SIP1 Mediates Cell-Fate Decisions between Neuroectoderm and Mesendoderm in Human Pluripotent Stem Cells

(2010) Zhenzhi Chng et al.   Cell Stem Cell

S-glutathionylation activates STIM1 and alters mitochondrial homeostasis

(2010) Brian J. Hawkins et al.   JOURNAL OF CELL BIOLOGY

MICU1 encodes a mitochondrial EF hand protein required for Ca2+ uptake

(2010) Fabiana Perocchi et al.   NATURE

Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis

(2009) Benjamin D. Humphreys et al.   AMERICAN JOURNAL OF PATHOLOGY

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Essential Role of Developmentally Activated Hypoxia-Inducible Factor 1α for Cardiac Morphogenesis and Function

(2008) Jaya Krishnan et al.   CIRCULATION RESEARCH

No place like home: anatomy and function of the stem cell niche

(2007) D. Leanne Jones et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY