A novel allosteric mechanism in the cysteine peptidase cathepsin K discovered by computational methods

Cathepsin K: a unique collagenolytic cysteine peptidase

(2013) Marko Novinec et al.   BIOLOGICAL CHEMISTRY

Allostery in Disease and in Drug Discovery

(2013) Ruth Nussinov et al.   CELL

Substrate inhibition and allosteric regulation by heparan sulfate of Trypanosoma brucei cathepsin L

(2012) Tatiana F.R. Costa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The spatial architecture of protein function and adaptation

(2012) Richard N. McLaughlin Jr et al.   NATURE

New approaches for dissecting protease functions to improve probe development and drug discovery

(2012) Edgar Deu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Hot Spots for Allosteric Regulation on Protein Surfaces

(2011) Kimberly A. Reynolds et al.   CELL

MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

(2011) N. D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

A simple and efficient protocol for the production of recombinant cathepsin V and other cysteine cathepsins in soluble form in Escherichia coli

(2011) Marko Novinec et al.   PROTEIN EXPRESSION AND PURIFICATION

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Conformational flexibility and allosteric regulation of cathepsin K

(2010) Marko Novinec et al.   BIOCHEMICAL JOURNAL

A comparative study of cancer proteins in the human protein-protein interaction network

(2010) Jingchun Sun et al.   BMC GENOMICS

An interdomain sector mediating allostery in Hsp70 molecular chaperones

(2010) Robert G Smock et al.   Molecular Systems Biology

Protein Sectors: Evolutionary Units of Three-Dimensional Structure

(2009) Najeeb Halabi et al.   CELL

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Kinetic analysis of effector modulation of butyrylcholinesterase-catalysed hydrolysis of acetanilides and homologous esters

(2008) Patrick Masson et al.   FEBS Journal

Allostery: Absence of a Change in Shape Does Not Imply that Allostery Is Not at Play

(2008) Chung-Jung Tsai et al.   JOURNAL OF MOLECULAR BIOLOGY

The Crystal and Molecular Structures of a Cathepsin K:Chondroitin Sulfate Complex

(2008) Zhenqiang Li et al.   JOURNAL OF MOLECULAR BIOLOGY

Allosteric regulation and catalysis emerge via a common route

(2008) Nina M Goodey et al.   Nature Chemical Biology

Surface Sites for Engineering Allosteric Control in Proteins

(2008) J. Lee et al.   SCIENCE