CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt

PI3K/Akt Pathway Activation Attenuates the Cytotoxic Effect of Methyl Jasmonate Toward Sarcoma Cells

(2015) Uri Elia et al.   NEOPLASIA

Truncation of the Catalytic Domain of the Cylindromatosis Tumor Suppressor Impairs Lung Maturation

(2015) Eirini Trompouki et al.   NEOPLASIA

PAI-1 in tissue fibrosis

(2011) Asish K. Ghosh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor

(2010) Chang-Hoon Woo et al.   FASEB JOURNAL

Dual function of MyD88 in RAS signaling and inflammation, leading to mouse and human cell transformation

(2010) Isabelle Coste et al.   JOURNAL OF CLINICAL INVESTIGATION

Ubiquitin chain cleavage: CYLD at work

(2010) Ramin Massoumi   TRENDS IN BIOCHEMICAL SCIENCES

WRAP53 Is Essential for Cajal Body Formation and for Targeting the Survival of Motor Neuron Complex to Cajal Bodies

(2010) Salah Mahmoudi et al.   PLOS BIOLOGY

CYLD: a tumor suppressor deubiquitinase regulating NF-κB activation and diverse biological processes

(2009) S-C Sun   CELL DEATH AND DIFFERENTIATION

The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation

(2009) W.-L. Yang et al.   SCIENCE

The fibrinolytic system and the regulation of lung epithelial cell proteolysis, signaling, and cellular viability

(2008) Sreerama Shetty et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Regulation of TGF-β family signaling by E3 ubiquitin ligases

(2008) Yasumichi Inoue et al.   CANCER SCIENCE

Transgelin is a direct target of TGF-β/Smad3-dependent epithelial cell migration in lung fibrosis

(2008) Haiying Yu et al.   FASEB JOURNAL

Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling

(2008) X. Guo et al.   GENES & DEVELOPMENT

From lung injury to fibrosis

(2008) Klaus Ley et al.   NATURE MEDICINE

PI3K pathway alterations in cancer: variations on a theme

(2008) T L Yuan et al.   ONCOGENE