Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor

Targeted Deletion of the Extracellular Signal-Regulated Protein Kinase 5 Attenuates Hypertrophic Response and Promotes Pressure Overload–Induced Apoptosis in the Heart

(2010) Tomomi E. Kimura et al.   CIRCULATION RESEARCH

ASK1 Regulates Cardiomyocyte Death but Not Hypertrophy in Transgenic Mice

(2009) Qinghang Liu et al.   CIRCULATION RESEARCH

Extracellular Signal-Regulated Kinase 5 SUMOylation Antagonizes Shear Stress–Induced Antiinflammatory Response and Endothelial Nitric Oxide Synthase Expression in Endothelial Cells

(2008) Chang-Hoon Woo et al.   CIRCULATION RESEARCH

Effects of MEK5/ERK5 Association on Small Ubiquitin-Related Modification of ERK5: Implications for Diabetic Ventricular Dysfunction After Myocardial Infarction

(2008) Tetsuro Shishido et al.   CIRCULATION RESEARCH

Protein quality control and degradation in cardiomyocytes

(2008) Xuejun Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

CHIP Deficiency Decreases Longevity, with Accelerated Aging Phenotypes Accompanied by Altered Protein Quality Control

(2008) J.-N. Min et al.   MOLECULAR AND CELLULAR BIOLOGY

Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes

(2008) Zhen Xu et al.   BMC STRUCTURAL BIOLOGY