Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells: Involvement of autophagy

Mitochondria released by cells undergoing TNF-α-induced necroptosis act as danger signals

(2014) A Maeda et al.   Cell Death & Disease

Live imaging and single-cell analysis reveal differential dynamics of autophagy and apoptosis

(2013) Yangqing Xu et al.   Autophagy

Functions of autophagy in normal and diseased liver

(2013) Mark J. Czaja et al.   Autophagy

Inhibition of hepatocyte autophagy increases tumor necrosis factor-dependent liver injury by promoting caspase-8 activation

(2013) M Amir et al.   CELL DEATH AND DIFFERENTIATION

Secretory versus Degradative Autophagy: Unconventional Secretion of Inflammatory Mediators

(2013) Shanya Jiang et al.   Journal of Innate Immunity

Autophagosomes form at ER–mitochondria contact sites

(2013) Maho Hamasaki et al.   NATURE

Cobalt Protoporphyrin Accelerates TFEB Activation and Lysosome Reformation during LPS-Induced Septic Insults in the Rat Heart

(2013) Kana Unuma et al.   PLoS One

Impairment of autophagy: From hereditary disorder to drug intoxication

(2013) Toshihiko Aki et al.   TOXICOLOGY

Inducer of heme oxygenase-1 cobalt protoporphyrin accelerates autophagy and suppresses oxidative damages during lipopolysaccharide treatment in rat liver

(2012) Kana Unuma et al.   HEPATOLOGY RESEARCH

Suppression of autophagy sensitizes Kupffer cells to endotoxin

(2012) Hiroo Fukada et al.   HEPATOLOGY RESEARCH

Elimination and active extrusion of liver mitochondrial proteins during lipopolysaccharide administration in rat

(2012) Kana Unuma et al.   HEPATOLOGY RESEARCH

Liver autophagy: physiology and pathology

(2012) M. Komatsu   JOURNAL OF BIOCHEMISTRY

Plasma nuclear and mitochondrial DNA levels as predictors of outcome in severe sepsis patients in the emergency room

(2012) Chia-Te Kung et al.   Journal of Translational Medicine

The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis

(2012) A. Roczniak-Ferguson et al.   Science Signaling

Autophagy intersections with conventional and unconventional secretion in tissue development, remodeling and inflammation

(2012) Vojo Deretic et al.   TRENDS IN CELL BIOLOGY

Transcriptional Activation of Lysosomal Exocytosis Promotes Cellular Clearance

(2011) Diego L. Medina et al.   DEVELOPMENTAL CELL

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

(2011) Nicolas Dupont et al.   EMBO JOURNAL

Heme oxygenase-1-mediated autophagy protects against hepatocyte cell death and hepatic injury from infection/sepsis in mice

(2011) Evie H. Carchman et al.   HEPATOLOGY

Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways

(2011) Michela Palmieri et al.   HUMAN MOLECULAR GENETICS

Crucial role for autophagy in degranulation of mast cells

(2011) Hiroko Ushio et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation

(2010) Dale W. Hailey et al.   CELL

Unconventional secretion of Acb1 is mediated by autophagosomes

(2010) Juan M. Duran et al.   JOURNAL OF CELL BIOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

A systematic review of experimental treatments for mitochondrial dysfunction in sepsis and multiple organ dysfunction syndrome

(2009) Anna J. Dare et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Activation of P2X7 Receptor Impairs Lysosomal Functions and Stimulates the Release of Autophagolysosomes in Microglial Cells

(2009) T. Takenouchi et al.   JOURNAL OF IMMUNOLOGY

A Gene Network Regulating Lysosomal Biogenesis and Function

(2009) Marco Sardiello et al.   SCIENCE

Structural Characterization of a Thiazoline-Containing Chromophore in an Orange Fluorescent Protein, Monomeric Kusabira Orange†‡

(2008) Akihiro Kikuchi et al.   BIOCHEMISTRY

Autophagy and multivesicular bodies: two closely related partners

(2008) C M Fader et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial Extrusion through the Cytoplasmic Vacuoles during Cell Death

(2008) Akihito Nakajima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE