Mitochondria released by cells undergoing TNF-α-induced necroptosis act as danger signals

Necroptosis induced by RIPK3 requires MLKL but not Drp1

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Blebs produced by actin–myosin contraction during apoptosis release damage-associated molecular pattern proteins before secondary necrosis occurs

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Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance

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Macrophage Clearance of Neutrophil Extracellular Traps Is a Silent Process

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RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3

(2013) John R. Lukens et al.   NATURE

Mitochondrial DAMPs Increase Endothelial Permeability through Neutrophil Dependent and Independent Pathways

(2013) Shiqin Sun et al.   PLoS One

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

(2012) Liming Sun et al.   CELL

The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways

(2012) Zhigao Wang et al.   CELL

RIP Kinase-Dependent Necrosis Drives Lethal Systemic Inflammatory Response Syndrome

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FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation

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Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

(2011) Claudia Günther et al.   NATURE

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Release of the mitochondrial endosymbiont helps explain sterile inflammation

(2010) S. L. Masters et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ins and outs of phospholipid asymmetry in the plasma membrane: roles in health and disease

(2009) Bengt Fadeel et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

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RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

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Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

(2008) Ann Cassidy-Stone et al.   DEVELOPMENTAL CELL

Identification of RIP1 kinase as a specific cellular target of necrostatins

(2008) Alexei Degterev et al.   Nature Chemical Biology