Resistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux
出版年份 2015 全文链接
标题
Resistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux
作者
关键词
-
出版物
Autophagy
Volume 11, Issue 10, Pages 1891-1904
出版商
Informa UK Limited
发表日期
2015-08-28
DOI
10.1080/15548627.2015.1085742
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Tumor Vessel Normalization by Chloroquine Independent of Autophagy
- (2014) Hannelore Maes et al. CANCER CELL
- Chloroquine synergizes sunitinib cytotoxicity via modulating autophagic, apoptotic and angiogenic machineries
- (2014) Amal Kamal Abdel-Aziz et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Randomized, Controlled, Double-Blind, Cross-Over Trial Assessing Treatment Preference for Pazopanib Versus Sunitinib in Patients With Metastatic Renal Cell Carcinoma: PISCES Study
- (2014) Bernard Escudier et al. JOURNAL OF CLINICAL ONCOLOGY
- Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
- (2014) Marco Gerlinger et al. NATURE GENETICS
- The Relevance of Testing the Efficacy of Anti-Angiogenesis Treatments on Cells Derived from Primary Tumors: A New Method for the Personalized Treatment of Renal Cell Carcinoma
- (2014) Renaud Grépin et al. PLoS One
- Mechanisms of resistance to anti-angiogenesis therapies
- (2013) Sandy Giuliano et al. BIOCHIMIE
- Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells
- (2013) M Santoni et al. BRITISH JOURNAL OF CANCER
- Slice cultures from head and neck squamous cell carcinoma: a novel test system for drug susceptibility and mechanisms of resistance
- (2013) M M Gerlach et al. BRITISH JOURNAL OF CANCER
- Inhibition of c-Met Reduces Lymphatic Metastasis in RIP-Tag2 Transgenic Mice
- (2013) B. Sennino et al. CANCER RESEARCH
- Neuropilin-2 Promotes Extravasation and Metastasis by Interacting with Endothelial 5 Integrin
- (2013) Y. Cao et al. CANCER RESEARCH
- The CXCL7/CXCR1/2 Axis Is a Key Driver in the Growth of Clear Cell Renal Cell Carcinoma
- (2013) R. Grepin et al. CANCER RESEARCH
- P-glycoprotein Mediates Drug Resistance via a Novel Mechanism Involving Lysosomal Sequestration
- (2013) Tetsuo Yamagishi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pazopanib versus Sunitinib in Metastatic Renal-Cell Carcinoma
- (2013) Robert J. Motzer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
- (2013) J. Gao et al. Science Signaling
- Guidelines for the use and interpretation of assays for monitoring autophagy
- (2012) Daniel J. Klionsky et al. Autophagy
- Autophagy Control by the VEGF-C/NRP-2 Axis in Cancer and Its Implication for Treatment Resistance
- (2012) M. J. Stanton et al. CANCER RESEARCH
- Investigational ABC transporter inhibitors
- (2012) Marco Falasca et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Intestinal Expression of MouseAbcg2/Breast Cancer Resistance Protein (BCRP) Gene Is under Control of Circadian Clock-activating Transcription Factor-4 Pathway
- (2012) Ahmed M. Hamdan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of Autophagy Enhances Sunitinib-Induced Cytotoxicity in Rat Pheochromocytoma PC12 cells
- (2012) Tatsuhiko Ikeda et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
- (2012) Marco Gerlinger et al. NEW ENGLAND JOURNAL OF MEDICINE
- Activating Transcription Factor 4 Confers a Multidrug Resistance Phenotype to Gastric Cancer Cells through Transactivation of SIRT1 Expression
- (2012) Hongwu Zhu et al. PLoS One
- A Validated Tumorgraft Model Reveals Activity of Dovitinib Against Renal Cell Carcinoma
- (2012) S. Sivanand et al. Science Translational Medicine
- Suppression of Tumor Invasion and Metastasis by Concurrent Inhibition of c-Met and VEGF Signaling in Pancreatic Neuroendocrine Tumors
- (2012) Barbara Sennino et al. Cancer Discovery
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Lysosomal Sequestration of Sunitinib: A Novel Mechanism of Drug Resistance
- (2011) K. J. Gotink et al. CLINICAL CANCER RESEARCH
- Brain accumulation of sunitinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by oral elacridar and sunitinib coadministration
- (2011) Seng Chuan Tang et al. INTERNATIONAL JOURNAL OF CANCER
- Bevacizumab can induce reactivity to VEGF-C and -D in human brain and tumour derived endothelial cells
- (2011) S. Grau et al. JOURNAL OF NEURO-ONCOLOGY
- Antiangiogenic therapy: impact on invasion, disease progression and metastasis
- (2011) John M. L. Ebos et al. Nature Reviews Clinical Oncology
- Sunitinib Acts Primarily on Tumor Endothelium rather than Tumor Cells to Inhibit the Growth of Renal Cell Carcinoma
- (2010) D. Huang et al. CANCER RESEARCH
- The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation
- (2010) Jiangbin Ye et al. EMBO JOURNAL
- Development and Characterization of Clinically Relevant Tumor Models From Patients With Renal Cell Carcinoma
- (2010) Jose A. Karam et al. EUROPEAN UROLOGY
- Phase III Trial of Bevacizumab Plus Interferon Alfa-2a in Patients With Metastatic Renal Cell Carcinoma (AVOREN): Final Analysis of Overall Survival
- (2010) Bernard Escudier et al. JOURNAL OF CLINICAL ONCOLOGY
- Targeting lysosomes to eradicate imatinib-resistant chronic myelogenous leukemia cells
- (2010) A Puissant et al. LEUKEMIA
- A high content screening assay for identifying lysosomotropic compounds
- (2010) Sashi Nadanaciva et al. TOXICOLOGY IN VITRO
- Anti-angiogenic tyrosine kinase inhibitors: what is their mechanism of action?
- (2009) Kristy J. Gotink et al. ANGIOGENESIS
- Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis
- (2009) John M.L. Ebos et al. CANCER CELL
- Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
- (2009) Marta Pàez-Ribes et al. CANCER CELL
- Sunitinib Inhibition of Stat3 Induces Renal Cell Carcinoma Tumor Cell Apoptosis and Reduces Immunosuppressive Cells
- (2009) H. Xin et al. CANCER RESEARCH
- Autophagy: links with the proteasome
- (2009) Trond Lamark et al. CURRENT OPINION IN CELL BIOLOGY
- Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
- (2009) Robert J. Motzer et al. JOURNAL OF CLINICAL ONCOLOGY
- Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells
- (2008) Ganna V Kalayda et al. BMC CANCER
- Sunitinib (Sutent, SU11248), a Small-Molecule Receptor Tyrosine Kinase Inhibitor, Blocks Function of the ATP-Binding Cassette (ABC) Transporters P-Glycoprotein (ABCB1) and ABCG2
- (2008) S. Shukla et al. DRUG METABOLISM AND DISPOSITION
- Autophagy fights disease through cellular self-digestion
- (2008) Noboru Mizushima et al. NATURE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started