MicroRNA-21 regulates T-cell apoptosis by directly targeting the tumor suppressor gene Tipe2

Signal transducer and activator of transcription (STAT)-3 regulates microRNA gene expression in chronic lymphocytic leukemia cells

(2013) Uri Rozovski et al.   Molecular Cancer

MiR-21 is up-regulated in psoriasis and suppresses T cell apoptosis

(2012) Florian Meisgen et al.   EXPERIMENTAL DERMATOLOGY

MiR-21 plays an Important Role in Radiation Induced Carcinogenesis in BALB/c Mice by Directly Targeting the Tumor Suppressor Gene Big-h3

(2012) Cong Liu et al.   International Journal of Biological Sciences

DNA Damage Induces NF-κB-dependent MicroRNA-21 Up-regulation and Promotes Breast Cancer Cell Invasion

(2012) Jixiao Niu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Anti-inflammatory TIPE2 Is an Inhibitor of the Oncogenic Ras

(2012) Yael Gus-Brautbar et al.   MOLECULAR CELL

Sprouty keeps bowel kinases regular in colon cancer, while miR-21 targets Sprouty

(2011) Mark R. Frey et al.   CANCER BIOLOGY & THERAPY

Targeting of the Tumor Suppressor GRHL3 by a miR-21-Dependent Proto-Oncogenic Network Results in PTEN Loss and Tumorigenesis

(2011) Charbel Darido et al.   CANCER CELL

miR-21 functionally interacts with the 3′UTR of chemokine CCL20 and down-regulates CCL20 expression in miR-21 transfected colorectal cancer cells

(2011) Benjamin Vicinus et al.   CANCER LETTERS

The transcriptional regulation of miR-21, its multiple transcripts and their implication in prostate cancer

(2011) Judit Ribas et al.   CELL CYCLE

The code within the code: microRNAs target coding regions

(2011) Joshua J. Forman et al.   CELL CYCLE

miR-21 targets the tumor suppressor RhoB and regulates proliferation, invasion and apoptosis in colorectal cancer cells

(2011) Ming Liu et al.   FEBS LETTERS

MicroRNA-21 Limits In Vivo Immune Response-Mediated Activation of the IL-12/IFN-  Pathway, Th1 Polarization, and the Severity of Delayed-Type Hypersensitivity

(2011) T. X. Lu et al.   JOURNAL OF IMMUNOLOGY

MicroRNAs in acute leukemia: from biological players to clinical contributors

(2011) D Schotte et al.   LEUKEMIA

The unique expression profile of human TIPE2 suggests new functions beyond its role in immune regulation

(2011) Li Zhang et al.   MOLECULAR IMMUNOLOGY

Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas

(2011) H-J Kwak et al.   ONCOGENE

PPARα Is Regulated by miR-21 and miR-27b in Human Liver

(2011) Katsuhiko Kida et al.   PHARMACEUTICAL RESEARCH

Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis

(2011) X. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of K-Ras-Dependent Lung Tumorigenesis by MicroRNA-21

(2010) Mark E. Hatley et al.   CANCER CELL

Anti-miR-21 oligonucleotide sensitizes leukemic K562 cells to arsenic trioxide by inducing apoptosis

(2010) Yumin Li et al.   CANCER SCIENCE

NF-κB targets miR-16 and miR-21 in gastric cancer: involvement of prostaglandin E receptors

(2010) Vivian Y. Shin et al.   CARCINOGENESIS

miR-21 downregulates the tumor suppressor P12CDK2AP1 and Stimulates Cell Proliferation and Invasion

(2010) Jun Zheng et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The magic and mystery of miR-21

(2010) Edward E. Morrisey   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-21 Expression in CD4+ T Cells Is Regulated by STAT3 and Is Pathologically Involved in Sézary Syndrome

(2010) Leslie van der Fits et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status

(2010) Xuan Zhou et al.   LABORATORY INVESTIGATION

Antisense oligonucleotide against miR-21 inhibits migration and induces apoptosis in leukemic K562 cells

(2010) Haiyan Hu et al.   LEUKEMIA & LYMPHOMA

STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

(2010) Dimitrios Iliopoulos et al.   MOLECULAR CELL

Tissue-specific expression of TIPE2 provides insights into its function

(2010) Guizhong Zhang et al.   MOLECULAR IMMUNOLOGY

MicroRNA-181a modulates gene expression of zinc finger family members by directly targeting their coding regions

(2010) Shenglin Huang et al.   NUCLEIC ACIDS RESEARCH

Upregulation of miR-21 by Ras in vivo and its role in tumor growth

(2010) D Frezzetti et al.   ONCOGENE

AP-1-Dependent miR-21 Expression Contributes to Chemoresistance in Cancer Stem Cell-Like SP Cells

(2010) Aya Misawa et al.   ONCOLOGY RESEARCH

BMPRII is a direct target of miR-21

(2009) W. Qin et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

miR-21as a key regulator of oncogenic processes

(2009) S. Duygu Selcuklu et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

MicroRNA Control in the Immune System: Basic Principles

(2009) Changchun Xiao et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma

(2009) Min Liu et al.   CELL RESEARCH

Down-regulation of TIPE2 mRNA expression in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

(2009) Di Li et al.   CLINICAL IMMUNOLOGY

Helicobacter pylori and gastric cancer: possible role of microRNAs in this intimate relationship

(2009) C. Belair et al.   CLINICAL MICROBIOLOGY AND INFECTION

TIPE2, a Negative Regulator of Innate and Adaptive Immunity that Maintains Immune Homeostasis

(2008) Honghong Sun et al.   CELL

MicroRNAs Are Differentially Expressed in Ulcerative Colitis and Alter Expression of Macrophage Inflammatory Peptide-2α

(2008) Feng Wu et al.   GASTROENTEROLOGY

MicroRNA involvement in hepatocellular carcinoma

(2008) Laura Gramantieri et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

miR-21: a small multi-faceted RNA

(2008) Anna M. Krichevsky et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

MicroRNA and cancer - focus on apoptosis

(2008) Yu Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

miR-21 Gene Expression Triggered by AP-1 Is Sustained through a Double-Negative Feedback Mechanism

(2008) Shuji Fujita et al.   JOURNAL OF MOLECULAR BIOLOGY

MicroRNAs and immunity: Novel players in the regulation of normal immune function and inflammation

(2008) Enikö Sonkoly et al.   SEMINARS IN CANCER BIOLOGY