Skp-cullin-F box E3 ligase component FBXL2 ubiquitinates Aurora B to inhibit tumorigenesis

Calmodulin protects Aurora B on the midbody to regulate the fidelity of cytokinesis

(2013) Rama K. Mallampalli et al.   CELL CYCLE

A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation

(2013) Bill B Chen et al.   NATURE IMMUNOLOGY

F-box protein FBXL2 targets cyclin D2 for ubiquitination and degradation to inhibit leukemic cell proliferation

(2012) B. B. Chen et al.   BLOOD

Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest

(2012) Tiffany A. Coon et al.   CELL CYCLE

FBXL2 is a ubiquitin E3 ligase subunit that triggers mitotic arrest

(2011) Bill B. Chen et al.   CELL CYCLE

Update on aurora kinase targeted therapeutics in oncology

(2011) Myke R Green et al.   Expert Opinion on Drug Discovery

F-box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrest

(2011) B B Chen et al.   ONCOGENE

SUMOylation modulates the function of Aurora-B kinase

(2010) G. Fernandez-Miranda et al.   JOURNAL OF CELL SCIENCE

SCFCyclin F controls centrosome homeostasis and mitotic fidelity through CP110 degradation

(2010) Vincenzo D’Angiolella et al.   NATURE

Dynamic regulation of cardiolipin by the lipid pump Atp8b1 determines the severity of lung injury in experimental pneumonia

(2010) Nancy B Ray et al.   NATURE MEDICINE

Distinct Roles of BARD1 Isoforms in Mitosis: Full-Length BARD1 Mediates Aurora B Degradation, Cancer-Associated BARD1  Scaffolds Aurora B and BRCA2

(2009) S. Ryser et al.   CANCER RESEARCH

A Last-Minute Rescue of Trapped Chromatin

(2009) Chun-Ting Chen et al.   CELL

Aurora B-Mediated Abscission Checkpoint Protects against Tetraploidization

(2009) Patrick Steigemann et al.   CELL

14-3-3ζ escorts CCTα for calcium-activated nuclear import in lung epithelia

(2009) Marianna Agassandian et al.   FASEB JOURNAL

Cross-talk between Remodeling andde NovoPathways Maintains Phospholipid Balance through Ubiquitination

(2009) Phillip L. Butler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Cul3–KLHL21 E3 ubiquitin ligase targets Aurora B to midzone microtubules in anaphase and is required for cytokinesis

(2009) Sarah Maerki et al.   JOURNAL OF CELL BIOLOGY

Masking of a Nuclear Signal Motif by Monoubiquitination Leads to Mislocalization and Degradation of the Regulatory Enzyme Cytidylyltransferase

(2009) B. B. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

GSK1070916, a potent Aurora B/C kinase inhibitor with broad antitumor activity in tissue culture cells and human tumor xenograft models

(2009) M. A. Hardwicke et al.   MOLECULAR CANCER THERAPEUTICS

The Arabidopsis thaliana F-Box Protein FBL17 Is Essential for Progression through the Second Mitosis during Pollen Development

(2009) Andi Gusti et al.   PLoS One

Plk1- and β-TrCP–dependent degradation of Bora controls mitotic progression

(2008) Akiko Seki et al.   JOURNAL OF CELL BIOLOGY

Control of chromosome stability by the β-TrCP–REST–Mad2 axis

(2008) Daniele Guardavaccaro et al.   NATURE