Protein tyrosine phosphatase 1B modulates GSK3β/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity

Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: Lessons learned from acetaminophen hepatotoxicity

(2012) Hartmut Jaeschke et al.   DRUG METABOLISM REVIEWS

Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity

(2012) Daniel J. Antoine et al.   JOURNAL OF HEPATOLOGY

Essential role of protein tyrosine phosphatase 1B in obesity-induced inflammation and peripheral insulin resistance during aging

(2011) Águeda González-Rodríguez et al.   AGING CELL

Src Subfamily Kinases Regulate Nuclear Export and Degradation of Transcription Factor Nrf2 to Switch Off Nrf2-mediated Antioxidant Activation of Cytoprotective Gene Expression

(2011) Suryakant K. Niture et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circulating apoptotic and necrotic cell death markers in patients with acute liver injury

(2011) Darren G. N. Craig et al.   LIVER INTERNATIONAL

Comparative effects of dietary flavanols on antioxidant defences and their response to oxidant-induced stress on Caco2 cells

(2010) Ildefonso Rodríguez-Ramiro et al.   EUROPEAN JOURNAL OF NUTRITION

Cytokeratin 18-based modification of the MELD score improves prediction of spontaneous survival after acute liver injury

(2010) Lars P. Bechmann et al.   JOURNAL OF HEPATOLOGY

IGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical efficacy of IGF-1R blockage

(2010) Victoria Tovar et al.   JOURNAL OF HEPATOLOGY

Hepatic insulin resistance is associated with increased apoptosis and fibrogenesis in nonalcoholic steatohepatitis and chronic hepatitis C

(2010) Carmelo García-Monzón et al.   JOURNAL OF HEPATOLOGY

Inhibition of PTP1B Restores IRS1-Mediated Hepatic Insulin Signaling in IRS2-Deficient Mice

(2009) A. Gonzalez-Rodriguez et al.   DIABETES

Histological patterns in drug-induced liver disease

(2009) R Ramachandran et al.   JOURNAL OF CLINICAL PATHOLOGY

High-Mobility Group Box-1 Protein and Keratin-18, Circulating Serum Proteins Informative of Acetaminophen-Induced Necrosis and Apoptosis In Vivo

(2009) Daniel J. Antoine et al.   TOXICOLOGICAL SCIENCES

PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling

(2008) X. Lu et al.   BLOOD

Protection of acetaminophen induced mitochondrial dysfunctions and hepatic necrosis via Akt-NF-κB pathway: Role of a novel plant protein

(2008) Ayantika Ghosh et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Dual Role of Interleukin-6 in Regulating Insulin Sensitivity in Murine Skeletal Muscle

(2008) I. Nieto-Vazquez et al.   DIABETES

Protein-tyrosine Phosphatase 1B Expression Is Induced by Inflammationin Vivo

(2008) Janice M. Zabolotny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: evidence for the role of oxidative stress on IRS-1 serine phosphorylation and insulin resistance

(2008) R Vinayagamoorthi et al.   JOURNAL OF ENDOCRINOLOGY