Functional cooperativity by direct interaction between PAK4 and MMP-2 in the regulation of anoikis resistance, migration and invasion in glioma

Discovery of Pyrroloaminopyrazoles as Novel PAK Inhibitors

(2012) Chuangxing Guo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Therapeutic Significance of Estrogen Receptor   Agonists in Gliomas

(2012) G. R. Sareddy et al.   MOLECULAR CANCER THERAPEUTICS

Nucleo-cytoplasmic shuttling of PAK4 modulates β-catenin intracellular translocation and signaling

(2011) Yan Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

LCH-7749944, a novel and potent p21-activated kinase 4 inhibitor, suppresses proliferation and invasion in human gastric cancer cells

(2011) Jian Zhang et al.   CANCER LETTERS

Notice of Retraction

(2011)   CARCINOGENESIS

A key role for Pak4 in proliferation and differentiation of neural progenitor cells

(2011) Yanmei Tian et al.   DEVELOPMENTAL BIOLOGY

Overcoming anoikis - pathways to anchorage-independent growth in cancer

(2011) M. C. Guadamillas et al.   JOURNAL OF CELL SCIENCE

PAK4 is required for regulation of the cell-cycle regulatory protein p21, and for control of cell-cycle progression

(2011) Tanya Nekrasova et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Suppression of MMP-2 Attenuates TNF-α Induced NF-κB Activation and Leads to JNK Mediated Cell Death in Glioma

(2011) Divya Kesanakurti et al.   PLoS One

MMP-2 siRNA Inhibits Radiation-Enhanced Invasiveness in Glioma Cells

(2011) Aruna Venkata Badiga et al.   PLoS One

Role for p21-activated kinase PAK4 in development of the mammalian heart

(2011) Tanya Nekrasova et al.   TRANSGENIC RESEARCH

p21-Activated Kinase-1 Promotes Aggressive Phenotype, Cell Proliferation, and Invasion in Gestational Trophoblastic Disease

(2010) Michelle K.Y. Siu et al.   AMERICAN JOURNAL OF PATHOLOGY

Selective matrix metalloproteinase (MMP) inhibitors in cancer therapy: Ready for prime time?

(2010) Stanley Zucker et al.   CANCER BIOLOGY & THERAPY

p21-activated Kinase 4 Phosphorylation of Integrin β5 Ser-759 and Ser-762 Regulates Cell Migration

(2010) Zhilun Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Subgroup II PAK-mediated phosphorylation regulates Ran activity during mitosis

(2010) Guillaume Bompard et al.   JOURNAL OF CELL BIOLOGY

PAK4: a pluripotent kinase that regulates prostate cancer cell adhesion

(2010) C. M. Wells et al.   JOURNAL OF CELL SCIENCE

ErbB2 requires integrin  5 for anoikis resistance via Src regulation of receptor activity in human mammary epithelial cells

(2010) K. K. Haenssen et al.   JOURNAL OF CELL SCIENCE

N-terminal interaction domain implicates PAK4 in translational regulation and reveals novel cellular localization signals

(2010) Simona Baldassa et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Integrin-mediated Cell Attachment Induces a PAK4-dependent Feedback Loop Regulating Cell Adhesion through Modified Integrin αvβ5 Clustering and Turnover

(2010) Zhilun Li et al.   MOLECULAR BIOLOGY OF THE CELL

p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients

(2010) M. K. Y. Siu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth

(2010) B. W. Murray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mustard NPR1, a mammalian IκB homologue inhibits NF-κB activation in human GBM cell lines

(2009) Divya Kesanakurti et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DGCR6L, a novel PAK4 interaction protein, regulates PAK4-mediated migration of human gastric cancer cell via LIMK1

(2009) Xiaodong Li et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Essential role for the Pak4 protein kinase in extraembryonic tissue development and vessel formation

(2009) Yanmei Tian et al.   MECHANISMS OF DEVELOPMENT

Pak4, a Novel Gab1 Binding Partner, Modulates Cell Migration and Invasion by the Met Receptor

(2009) G. N. Paliouras et al.   MOLECULAR AND CELLULAR BIOLOGY

PAK signaling in oncogenesis

(2009) P R Molli et al.   ONCOGENE

Oncogenic EGFR Signaling Networks in Glioma

(2009) P. H. Huang et al.   Science Signaling

A PAK4–LIMK1 pathway drives prostate cancer cell migration downstream of HGF

(2008) Tasneem Ahmed et al.   CELLULAR SIGNALLING

The Pak4 Protein Kinase Plays a Key Role in Cell Survival and Tumorigenesis in Athymic Mice

(2008) Y. Liu et al.   MOLECULAR CANCER RESEARCH