Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription

Glycogen Synthase Kinase-3 (GSK-3) Inhibitors for the Treatment of Alzheimers Disease

(2012) Miguel Medina et al.   CURRENT PHARMACEUTICAL DESIGN

A novel parkin-mediated transcriptional function links p53 to familial Parkinson’s disease

(2011) Cristina Alves da Costa et al.   CELL CYCLE

What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease

(2011) Olga Corti et al.   PHYSIOLOGICAL REVIEWS

To repress or not to repress: This is the guardian's question

(2011) John L. Rinn et al.   TRENDS IN CELL BIOLOGY

Novel Research Horizons for Presenilins and γ-Secretases in Cell Biology and Disease

(2010) Bart De Strooper et al.   Annual Review of Cell and Developmental Biology

Tau in Alzheimer Disease and Related Tauopathies

(2010) K. Iqbal et al.   Current Alzheimer Research

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

(2010) Inna Kuperstein et al.   EMBO JOURNAL

Parkin Suppresses c-Jun N-terminal kinase-induced cell death via transriptional regulation in Drosophila

(2010) Soojin Hwang et al.   MOLECULES AND CELLS

The role of parkin in familial and sporadic Parkinson's disease

(2010) Ted M. Dawson et al.   MOVEMENT DISORDERS

p53 Is Regulated by and Regulates Members of the γ-Secretase Complex

(2010) Frédéric Checler et al.   Neurodegenerative Diseases

Transcriptional regulation of the murine Presenilin-2 gene reveals similarities and differences to its human orthologue

(2009) Hadile Ounallah-Saad et al.   GENE

Parkin promotes intracellular A 1-42 clearance

(2009) M. P. Burns et al.   HUMAN MOLECULAR GENETICS

p53-dependent control of transactivation of the Pen2 promoter by presenilins

(2009) J. Dunys et al.   JOURNAL OF CELL SCIENCE

Aminopeptidase A contributes to the N-terminal truncation of amyloid β-peptide

(2009) Jean Sevalle et al.   JOURNAL OF NEUROCHEMISTRY

Parkin reverses intracellular β-amyloid accumulation and its negative effects on proteasome function

(2009) Kenneth M. Rosen et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease

(2009) Cristine Alves da Costa et al.   NATURE CELL BIOLOGY

Parkinson's disease-associated parkin colocalizes with Alzheimer's disease and multiple sclerosis brain lesions

(2009) Maarten E. Witte et al.   NEUROBIOLOGY OF DISEASE

Intracellular Amyloid β-Protein As a Therapeutic Target for Treating Alzheimers Disease

(2008) Y. Ohyagi   Current Alzheimer Research

Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: implications for Alzheimer disease

(2008) Nikolai D Belyaev et al.   EMBO REPORTS

Biochemistry of Tau in Alzheimer’s disease and related neurological disorders

(2008) Nicolas Sergeant et al.   Expert Review of Proteomics

Parkin Regulates Eg5 Expression by Hsp70 Ubiquitination-dependent Inactivation of c-Jun NH2-terminal Kinase

(2008) Min Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY