4.6 Review Book Chapter

Nutrigenomics and Personalized Diets: What Will They Mean for Food?

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DOI: 10.1146/annurev.food.102308.124147

关键词

proteomics; metabolomics; health assessment; nutritional phenotype; personalized foods; functional foods

资金

  1. NIEHS NIH HHS [P42 ES004699, P42ES004699, P01ES11269, P01 ES011269] Funding Source: Medline
  2. NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES [P42ES004699, P01ES011269] Funding Source: NIH RePORTER

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The modern food system feeds six billion people with remarkable diversity, safety, and nutrition. Yet, the current rise in diet-related diseases is compromising health and devaluing many aspects of modern agriculture. Steps to increase the nutritional quality of individual foods will assist in personalizing health and in guiding individuals to achieve superior health. Nutrigenomics is the scientific field of the genetic basis for varying susceptibilities to disease and the diverse responses to foods. Although some of these genetic determinants will be simple and amenable to personal genotyping as the means to predict health, in practice most will not. As a result, genotyping will not be the secret to personalizing diet and health. Human assessment technologies from imaging to proteomics and metabolomics are providing tools to both understand and accurately assess the nutritional phenotype of individuals. The business models are also emerging to bring these assessment capabilities to industrial practice, in which consumers will know more about their personal health and seek personal solutions.

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