3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors

Epigenetic regulation of fetal globin gene expression in adult erythroid cells

(2015) Gordon D. Ginder   Translational Research

Epigenetics of idiopathic pulmonary fibrosis

(2015) Ivana V. Yang et al.   Translational Research

Physicochemical modifications of histones and their impact on epigenomics

(2014) Federico Andreoli et al.   DRUG DISCOVERY TODAY

Epigenetic modifications of Nrf2-mediated glutamate–cysteine ligase: implications for the development of diabetic retinopathy and the metabolic memory phenomenon associated with its continued progression

(2014) Manish Mishra et al.   FREE RADICAL BIOLOGY AND MEDICINE

Design, synthesis and antiproliferative activity studies of novel 1,2,3-triazole–dithiocarbamate–urea hybrids

(2013) Ying-Chao Duan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design and synthesis of novel 1,2,3-triazole-dithiocarbamate hybrids as potential anticancer agents

(2013) Ying-Chao Duan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Triazole–Dithiocarbamate Based Selective Lysine Specific Demethylase 1 (LSD1) Inactivators Inhibit Gastric Cancer Cell Growth, Invasion, and Migration

(2013) Yi-Chao Zheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction

(2013) Lihong Shi et al.   NATURE MEDICINE

Suppression of Gluconeogenic Gene Expression by LSD1-Mediated Histone Demethylation

(2013) Dongning Pan et al.   PLoS One

A Novel Selective LSD1/KDM1A Inhibitor Epigenetically Blocks Herpes Simplex Virus Lytic Replication and Reactivation from Latency

(2013) Y. Liang et al.   mBio

Synthesis and Evaluation of Novel Cyclic Peptide Inhibitors of Lysine-Specific Demethylase 1

(2013) Isuru R. Kumarasinghe et al.   ACS Medicinal Chemistry Letters

Low Molecular Weight Amidoximes that Act as Potent Inhibitors of Lysine-Specific Demethylase 1

(2012) Stuart Hazeldine et al.   JOURNAL OF MEDICINAL CHEMISTRY

An Overview of Phenylcyclopropylamine Derivatives: Biochemical and Biological Significance and Recent Developments

(2012) Mohammed Naseer Ahmed Khan et al.   MEDICINAL RESEARCH REVIEWS

Brain-Penetrant LSD1 Inhibitors Can Block Memory Consolidation

(2011) Ramesh Neelamegam et al.   ACS Chemical Neuroscience

Lysine Demethylases Inhibitors

(2011) Takayoshi Suzuki et al.   JOURNAL OF MEDICINAL CHEMISTRY

Polyamine-based small molecule epigenetic modulators

(2011) Shiv K. Sharma et al.   MedChemComm

Structurally Designedtrans-2-Phenylcyclopropylamine Derivatives Potently Inhibit Histone Demethylase LSD1/KDM1,,§

(2010) Shinya Mimasu et al.   BIOCHEMISTRY

Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers

(2010) Shinya Hayami et al.   INTERNATIONAL JOURNAL OF CANCER

(Bis)urea and (Bis)thiourea Inhibitors of Lysine-Specific Demethylase 1 as Epigenetic Modulators

(2010) Shiv K. Sharma et al.   JOURNAL OF MEDICINAL CHEMISTRY

Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy

(2009) J. H. Schulte et al.   CANCER RESEARCH

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

(2009) Soyoung Lim et al.   CARCINOGENESIS