A Novel Selective LSD1/KDM1A Inhibitor Epigenetically Blocks Herpes Simplex Virus Lytic Replication and Reactivation from Latency
出版年份 2013 全文链接
标题
A Novel Selective LSD1/KDM1A Inhibitor Epigenetically Blocks Herpes Simplex Virus Lytic Replication and Reactivation from Latency
作者
关键词
-
出版物
mBio
Volume 4, Issue 1, Pages -
出版商
American Society for Microbiology
发表日期
2013-02-06
DOI
10.1128/mbio.00558-12
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting the JMJD2 Histone Demethylases to Epigenetically Control Herpesvirus Infection and Reactivation from Latency
- (2013) Y. Liang et al. Science Translational Medicine
- The Histone Demethylase KDM1A Sustains the Oncogenic Potential of MLL-AF9 Leukemia Stem Cells
- (2012) William J. Harris et al. CANCER CELL
- Herpes Simplex Virus 1 DNA Is in Unstable Nucleosomes throughout the Lytic Infection Cycle, and the Instability of the Nucleosomes Is Independent of DNA Replication
- (2012) J. J. Lacasse et al. JOURNAL OF VIROLOGY
- Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia
- (2012) Tino Schenk et al. NATURE MEDICINE
- Over-Expression of LSD1 Promotes Proliferation, Migration and Invasion in Non-Small Cell Lung Cancer
- (2012) Tangfeng Lv et al. PLoS One
- CMX001 Potentiates the Efficacy of Acyclovir in Herpes Simplex Virus Infections
- (2011) Mark N. Prichard et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Regulation of chromatin by histone modifications
- (2011) Andrew J Bannister et al. CELL RESEARCH
- Epigenetics: deciphering its role in diabetes and its chronic complications
- (2011) Louisa M Villeneuve et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Lysine Demethylases Inhibitors
- (2011) Takayoshi Suzuki et al. JOURNAL OF MEDICINAL CHEMISTRY
- Enhancer function: new insights into the regulation of tissue-specific gene expression
- (2011) Chin-Tong Ong et al. NATURE REVIEWS GENETICS
- Chromatin structure of adenovirus DNA throughout infection
- (2011) A. N. Giberson et al. NUCLEIC ACIDS RESEARCH
- Promises and challenges of anticancer drugs that target the epigenome
- (2011) Inge Verbrugge et al. Epigenomics
- Epigenetics of autoimmune diabetes
- (2011) Sundararajan Jayaraman Epigenomics
- Activation of HIV Transcription by the Viral Tat Protein Requires a Demethylation Step Mediated by Lysine-specific Demethylase 1 (LSD1/KDM1)
- (2011) Naoki Sakane et al. PLoS Pathogens
- Epigenetic regulation of latent HSV-1 gene expression
- (2010) David C. Bloom et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Targeting epigenetic enzymes for drug discovery
- (2010) Robert A Copeland et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers
- (2010) Shinya Hayami et al. INTERNATIONAL JOURNAL OF CANCER
- Efficacy of CMX001 against Herpes Simplex Virus Infections in Mice and Correlations with Drug Distribution Studies
- (2010) Debra C. Quenelle et al. JOURNAL OF INFECTIOUS DISEASES
- Suppression of inflammation by a synthetic histone mimic
- (2010) Edwige Nicodeme et al. NATURE
- Epigenetic modifications as therapeutic targets
- (2010) Theresa K Kelly et al. NATURE BIOTECHNOLOGY
- Changes to Euchromatin on LAT and ICP4 Following Reactivation Are More Prevalent in an Efficiently Reactivating Strain of HSV-1
- (2010) Clinton C. Creech et al. PLoS One
- The Epigenetic Landscape of Latent Kaposi Sarcoma-Associated Herpesvirus Genomes
- (2010) Thomas Günther et al. PLoS Pathogens
- Chromatin organization of gammaherpesvirus latent genomes
- (2009) Italo Tempera et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Epigenetic regulation of latent Epstein–Barr virus promoters
- (2009) Maria Takacs et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Chromatin structure regulates human cytomegalovirus gene expression during latency, reactivation and lytic infection
- (2009) John Sinclair Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Papillomavirus interaction with cellular chromatin
- (2009) Jianxin You Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Epigenetic Therapy: Histone Acetylation, DNA Methylation and Anti-Cancer Drug Discovery
- (2009) A. Ganesan et al. CURRENT CANCER DRUG TARGETS
- Epigenetic opportunities and challenges in cancer
- (2009) Jonathan D. Best et al. DRUG DISCOVERY TODAY
- Epigenetics of neurological cancers
- (2009) Shaun D Fouse et al. Future Oncology
- The Polycomb Group Protein Bmi1 Binds to the Herpes Simplex Virus 1 Latent Genome and Maintains Repressive Histone Marks during Latency
- (2009) D. L. Kwiatkowski et al. JOURNAL OF VIROLOGY
- Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies
- (2009) Rocio G Urdinguio et al. LANCET NEUROLOGY
- Inhibition of the histone demethylase LSD1 blocks α-herpesvirus lytic replication and reactivation from latency
- (2009) Yu Liang et al. NATURE MEDICINE
- Protein methyltransferases as a target class for drug discovery
- (2009) Robert A. Copeland et al. NATURE REVIEWS DRUG DISCOVERY
- Chromatinisation of herpesvirus genomes
- (2009) Christina Paulus et al. REVIEWS IN MEDICAL VIROLOGY
- Chromatin organization and virus gene expression
- (2008) Paul M. Lieberman JOURNAL OF CELLULAR PHYSIOLOGY
- Chromatin control of herpes simplex virus lytic and latent infection
- (2008) David M. Knipe et al. NATURE REVIEWS MICROBIOLOGY
- Epigenetic regulation and the pathogenesis of systemic lupus erythematosus
- (2008) Yujun Pan et al. Translational Research
- Role for A-Type Lamins in Herpesviral DNA Targeting and Heterochromatin Modulation
- (2008) Lindsey Silva et al. PLoS Pathogens
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