Article
Multidisciplinary Sciences
Junichi Sugiura, Makoto Watanabe, Saki Nobuta, Akihiko Okamura, Atsushi Kyodo, Takuya Nakamura, Kazutaka Nogi, Satomi Ishihara, Yukihiro Hashimoto, Tomoya Ueda, Ayako Seno, Kenji Onoue, Tsunenari Soeda, Yoshihiko Saito
Summary: CCTA is useful in predicting CNs detected by OCT, and analyzing CCTA parameters can help identify CNs more accurately.
SCIENTIFIC REPORTS
(2022)
Article
Cardiac & Cardiovascular Systems
Yu Takahashi, Hiromasa Otake, Shoichi Kuramitsu, Masanobu Ohya, Kazunori Horie, Hiroyoshi Kawamoto, Futoshi Yamanaka, Masahiro Natsuaki, Hiroki Shiomi, Gaku Nakazawa, Kenji Ando, Kazushige Kadota, Shigeru Saito, Takeshi Kimura
Summary: The study found that in-stent calcified nodules (IS-CN) may be one of the underlying mechanisms of second-generation drug-eluting stent (G2-DES) stent thrombosis (ST). Additionally, patients with IS-CN were more likely to experience target lesion revascularisation (TLR) after the index ST events, indicating the need for careful clinical follow-up in these patients.
Review
Environmental Sciences
J. Escudero, J. L. Munoz, T. Morera-Herreras, R. Hernandez, J. Medrano, S. Domingo-Echaburu, D. Barcelo, G. Orive, U. Lertxundi
Summary: Antipsychotics, a group of drugs used to treat various diseases, have a complex pharmacological profile and act on multiple receptors found in different living beings. They may have a significant impact on aquatic wildlife and bioaccumulate through the food web.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Review
Microbiology
Fang Wang, RunHua Han, Shi Chen
Summary: Talaromycosis is an invasive mycosis caused by Talaromyces marneffei, and it is endemic in tropical and subtropical Asia. The infection rate is high, with approximately 17,300 cases diagnosed annually, and the mortality rate is extremely high. However, despite its impact on immunocompromised individuals and the increase in cases among those without HIV, global attention to diagnostic and therapeutic approaches for talaromycosis has been lacking. Understanding the pathogenic mechanism of T. marneffei has been limited, but recent research breakthroughs have shed light on its growth biology and interaction with the host immune response and environmental stimuli.
CLINICAL MICROBIOLOGY REVIEWS
(2023)
Article
Cell Biology
Dennis Mangan
Summary: Iron is essential for living organisms, but excessive accumulation can lead to health issues, age-related diseases, and shortened lifespan. Blocking iron absorption can extend lifespan, while controlling body iron stores may be an important intervention for health and longevity.
Review
Health Care Sciences & Services
Natthapon Angsubhakorn, Nicolas Kang, Colleen Fearon, Chol Techorueangwiwat, Pooja Swamy, Emmanouil S. Brilakis, Aditya S. Bharadwaj
Summary: Coronary artery calcification is common and has negative effects on percutaneous coronary intervention success and cardiovascular events risk. This review discusses various methods for modifying calcified plaque and emphasizes the importance of intravascular imaging for characterization. An algorithm for tailoring calcium modification therapy based on coronary lesion characteristics is also presented.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Review
Medicine, General & Internal
Gianluca Caiazzo, Carlo Di Mario, Elvin Kedhi, Giuseppe De Luca
Summary: The amount of coronary calcium is closely related to the severity of atherosclerosis and future cardiac events. Calcified coronary lesions not only pose a higher risk of immediate complications during percutaneous coronary interventions (PCI), but also have a significant impact on long-term stent failure and prognosis. In order to improve the successful treatment of these lesions, accurate identification of calcified plaques and analysis of their distribution within the vessel wall using intracoronary imaging are important.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Kojiro Minato, Motohiko Yamazaki, Takuya Yagi, Tetsuhiro Hirata, Masaki Tominaga, Kyoryoku You, Hiroyuki Ishikawa
Summary: The study aimed to evaluate the added value of the one-shot dual-energy subtraction (DES) method in distinguishing calcified from non-calcified nodules on chest radiographs. The soft tissue image obtained by the DES method with a flat-panel detector was compared with the standard image alone. The results showed that the accuracy and diagnostic performance of the radiologists improved after adding the soft tissue images, especially for less experienced radiologists.
SCIENTIFIC REPORTS
(2023)
Review
Chemistry, Multidisciplinary
Marta Kolodziejska, Kamila Jankowska, Marta Klak, Michal Wszola
Summary: Chitosan, with its unique chemical, biological, and physical properties, is extensively used in tissue engineering as a main component in biomaterials. It can be modified and blended to meet specific requirements, making it versatile for various applications such as membranes, scaffolds, drug carriers, and hydrogels.
Article
Cardiac & Cardiovascular Systems
Takeshi Tada, Katsuya Miura, Akihiro Ikuta, Masanobu Ohya, Takenobu Shimada, Kohei Osakada, Makoto Takamatsu, Yuya Taguchi, Shunsuke Kubo, Hiroyuki Tanaka, Yasushi Fuku, Kazushige Kadota
Summary: This study aimed to investigate the prevalence, predictors, and midterm outcomes of ISR lesions with CN. The results showed that the prevalence of ISR lesions with CN was 4.9%. Calcified lesions, incomplete stent apposition, haemodialysis, and female gender were found to be associated with CN formation. ISR lesions with CN were associated with poorer midterm outcomes compared to those without CN.
Review
Biochemistry & Molecular Biology
Kamil Karolczak, Cezary Watala
Summary: Platelets are key regulators of TGF beta levels, but there is limited research on developing platelet-directed therapies; however, promising reports suggest that platelet TGF beta may play specific roles in cardiovascular diseases, liver fibrosis, tumor metastasis, cerebral malaria, and inflammatory cell function regulation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Biochemistry & Molecular Biology
Beata Franczyk, Jill Dybiec, Weronika Frak, Julia Krzeminska, Joanna Kucmierz, Ewelina Mlynarska, Magdalena Szlagor, Magdalena Wronka, Jacek Rysz
Summary: This review focuses on the main pathophysiological mechanisms of coronary artery spasm (CAS), including endothelial dysfunction, chronic inflammation, oxidative stress, smooth muscle hypercontractility, atherosclerosis and thrombosis, and mutations leading to deficient ALDH2 activity. These findings offer novel insights into the underlying mechanisms of CAS and may guide the development of diagnostic and therapeutic targets for cardiovascular diseases in the future.
Editorial Material
Hematology
Alberto Vera, Fernando Rivero, Jorge Salamanca, Teresa Alvarado-Casas, Fernando Alfonso
Summary: The article describes a case of thrombotic coronary side effect in a 72-year-old woman with advanced breast cancer following treatment with abemaciclib, highlighting the need to be cautious of potential cardiotoxic effects of new cancer treatment drugs.
THROMBOSIS AND HAEMOSTASIS
(2021)
Review
Microbiology
Silvere D. Zaongo, Fazhen Zhang, Yaokai Chen
Summary: In the first part of this article, an extensive review of the diagnostic tools used by physicians in the management of talaromycosis cases is provided. Challenges and perspectives for the discovery of more accurate and reliable diagnostic approaches are discussed. The second part of the review focuses on the drugs used to prevent and treat T. marneffei infection, including alternative therapeutic options and potential drug resistance reported in contemporary literature.
Article
Radiology, Nuclear Medicine & Medical Imaging
Wei-Hua Yin, Hong-Yue Wang, Yang Sun, Xiang-Nan Li, Zhong-Fei Lu, Yun-Qiang An, Zhi-Hui Hou, Jie Zhang, Xin-Shuang Ren, U. Joseph Schoepf, Yan Zhang, Bin Lu
Summary: The study found that the diamond-attenuation-sign (DAS) could more accurately identify unstable atherosclerotic plaques compared to the napkin-ring sign (NRS), and DAS was more frequently seen on CCTA exams.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2022)
Letter
Cardiac & Cardiovascular Systems
Georgia Vogiatzi, Konstantinos Toutouzas, Antonis Karanasos, Andreas Synetos, Georgios Latsios, Eleftherios Tsiamis, Dimitris Tousoulis
HELLENIC JOURNAL OF CARDIOLOGY
(2019)
Meeting Abstract
Cardiac & Cardiovascular Systems
Kenichiro Otsuka, Martin Villiger, Antonios Karanasos, Laurens van Zandvoort, Pallavi Doradla, Jian Ren, Norman Lippok, Joost Daemen, Roberto Diletti, Robert-Jan van Geuns, Felix Zijlstra, Gijs van Soest, Jouke Dijkstra, Seemantini Nadkarni, Evelyn Regar, Brett Bouma
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2019)
Meeting Abstract
Cardiac & Cardiovascular Systems
Antonios Karanasos, Konstantinos Toutouzas, Kostas Tyrovolas, Michael Efremidis, Dimitris Tsiachris, Athanasios Kordalis, Maria Karmpalioti, Constantina Aggeli, Christodoulos Stefanadis, Kostas Gatzoulis, Dimitris Tousoulis
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2019)
Article
Cardiac & Cardiovascular Systems
Pallavi Doradla, Kenichiro Otsuka, Abhijay Nadkarni, Martin Villiger, Antonios Karanasos, Laurens J. C. van Zandvoort, Jouke Dijkstra, Felix Zijlstra, Gijs van Soest, Joost Daemen, Evelyn Regar, Brett E. Bouma, Seemantini K. Nadkarni
JACC-CARDIOVASCULAR IMAGING
(2020)
Article
Cardiac & Cardiovascular Systems
Kenichiro Otsuka, Martin Villiger, Antonios Karanasos, Laurens J. C. van Zandvoort, Pallavi Doradla, Jian Ren, Norman Lippok, Joost Daemen, Roberto Diletti, Robert-Jan van Geuns, Felix Zijlstra, Gijs van Soest, Jouke Dijkstra, Seemantini K. Nadkarni, Evelyn Regar, Brett E. Bouma
JACC-CARDIOVASCULAR IMAGING
(2020)
Letter
Cardiac & Cardiovascular Systems
George Latsios, Kostas Toutouzas, Antonis Karanasos, Andreas Synetos, Maria Drakopoulou, Constantina Aggeli, Dimitris Tousoulis
Summary: In this case report, a novel collagen plug-based device (Manta (c) device) was successfully used for arterial hemostasis during TF-TAVI in a patient with extremely hostile peripheral vessel anatomy due to calcification. This demonstrates the efficacy of the device in challenging situations.
HELLENIC JOURNAL OF CARDIOLOGY
(2021)
Meeting Abstract
Cardiac & Cardiovascular Systems
Kenichiro Otsuka, Martin Villiger, Laurens van Zandvoort, Tara Neleman, Antonios Karanasos, Jouke Dijkstra, Seemantini Nadkarni, Evelyn Regar, Joost Daemen, Brett Bouma
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2020)
Meeting Abstract
Cardiac & Cardiovascular Systems
Kenichiro Otsuka, Martin Villiger, Laurens van Zandvoort, Tara Neleman, Antonios Karanasos, Jouke Dijkstra, Evelyn Regar, Seemantini Nadkarni, Joost Daemen, Brett Bouma
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2020)
Meeting Abstract
Cardiac & Cardiovascular Systems
Kenichiro Otsuka, Martin Villiger, Laurens J. van Zandvoort, Joost Daemen, Antonios V. Karanasos, Gijs van Soest, Jouke Dijkstra, Seemantini Nadkarni, Evelyn Regar, Brett E. Bouma
Meeting Abstract
Cardiac & Cardiovascular Systems
Antonios Karanasos, Konstantinos Toutouzas, Kostas Tyrovolas, Dimitris Tsiachris, Michael Efremidis, Athanasios Kordalis, Maria Karmpalioti, Constantina Aggeli, Christodoulos Stefanadis, Dimitrios Tousoulis
Meeting Abstract
Cardiac & Cardiovascular Systems
K. Otsuka, M. Villiger, A. Karanasos, L. J. C. Van Zandvoort, P. Doradla, J. Daemen, R. Diletti, R. J. Van Geuns, F. Zijlstra, G. Van Soest, J. Dijkstra, S. K. Nadkarni, E. Regar, B. E. Bouma
EUROPEAN HEART JOURNAL
(2019)
Meeting Abstract
Cardiac & Cardiovascular Systems
I. Matsoukis, K. Toutouzas, C. Patsa, N. Anousakis-Vlachochristou, K. Triantafyllou, M. Kantzanou, M. Drakopoulou, E. Tsiamis, G. Latsios, A. Synetos, A. Karanasos, E. Petridou, D. Tousoulis
EUROPEAN HEART JOURNAL
(2019)
Meeting Abstract
Cardiac & Cardiovascular Systems
A. Karanasos, K. Toutouzas, K. Tyrovolas, M. Efremidis, D. Tsiachris, A. Kordalis, M. Karmpalioti, C. Aggeli, E. Prappa, S. Karagiannis, C. Stefanadis, K. Gatzoulis, D. Tousoulis
EUROPEAN HEART JOURNAL
(2019)
Article
Cardiac & Cardiovascular Systems
George Latsios, Konstantinos Toutouzas, Antonios Karanasos, Dimitrios Tousoulis
CARDIOVASCULAR REVASCULARIZATION MEDICINE
(2019)
Review
Cardiac & Cardiovascular Systems
Vasiliki Katsi, Konstantinos Konstantinou, Antonios Karanasos, Ilias Tolis, Sophia Vaina, Eleftherios Tsiamis, Dimitnos Tousoulis
OPEN CARDIOVASCULAR MEDICINE JOURNAL
(2019)
