CARD8 is a negative regulator for NLRP3 inflammasome, but mutant NLRP3 in cryopyrin-associated periodic syndromes escapes the restriction

Dangerous Liaisons: Mitochondrial DNA Meets the NLRP3 Inflammasome

(2012) Fabio Martinon   IMMUNITY

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP

(2012) Geun-Shik Lee et al.   NATURE

Regulation of inflammasome signaling

(2012) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Sensing and reacting to microbes through the inflammasomes

(2012) Luigi Franchi et al.   NATURE IMMUNOLOGY

Genetic and Molecular Basis of Inflammasome-mediated Disease

(2011) Hal M. Hoffman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetics of monogenic autoinflammatory diseases: past successes, future challenges

(2011) Ivona Aksentijevich et al.   Nature Reviews Rheumatology

Caspase Recruitment Domain-containing Protein 8 (CARD8) Negatively Regulates NOD2-mediated Signaling

(2010) Oliver von Kampen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of inflammation in gout

(2010) Nathalie Busso et al.   ARTHRITIS RESEARCH & THERAPY

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Inflammasomes: too big to miss

(2009) Andrea Stutz et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of Inflammasomes Requires Intracellular Redistribution of the Apoptotic Speck-Like Protein Containing a Caspase Recruitment Domain

(2009) N. B. Bryan et al.   JOURNAL OF IMMUNOLOGY

Gene polymorphisms in the NALP3 inflammasome are associated with interleukin-1 production and severe inflammation: Relation to common inflammatory diseases?

(2008) Deepti Verma et al.   ARTHRITIS AND RHEUMATISM

Novel isoforms of the CARD8 (TUCAN) gene evade a nonsense mutation

(2008) Richard D Bagnall et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

No association of the CARD8 (TUCAN) c.30T>A (p.C10X) variant with Crohnʼs disease: A study in 3 independent European cohorts

(2007) Carsten Büning et al.   INFLAMMATORY BOWEL DISEASES