The role of the circadian clock in rheumatoid arthritis

Chronic Shift-Lag Alters the Circadian Clock of NK Cells and Promotes Lung Cancer Growth in Rats

(2012) R. W. Logan et al.   JOURNAL OF IMMUNOLOGY

Timing to Perfection: The Biology of Central and Peripheral Circadian Clocks

(2012) Urs Albrecht   NEURON

Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines

(2012) R. Narasimamurthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Small Molecule Activators of Cryptochrome

(2012) T. Hirota et al.   SCIENCE

Disruption of rhythms of molecular clocks in primary synovial fibroblasts of patients with osteoarthritis and rheumatoid arthritis, role of IL-1β/TNF

(2012) Stefanie Haas et al.   ARTHRITIS RESEARCH & THERAPY

The metabolic syndrome: The crossroads between rheumatoid arthritis and cardiovascular risk

(2011) Elisa Gremese et al.   AUTOIMMUNITY REVIEWS

Widespread Negative Response Elements Mediate Direct Repression by Agonist- Liganded Glucocorticoid Receptor

(2011) Milan Surjit et al.   CELL

15-deoxy-Δ12,14-prostaglandin-J2 and ciglitazone inhibit TNF-α-induced matrix metalloproteinase 13 production via the antagonism of NF-κB activation in human synovial fibroblasts

(2011) Tzu-Hung Lin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Diurnal Rhythm of Circulating Nicotinamide Phosphoribosyltransferase (Nampt/Visfatin/PBEF): Impact of Sleep Loss and Relation to Glucose Metabolism

(2011) Christian Benedict et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Circadian Variation of the Response of T Cells to Antigen

(2011) E. E. Fortier et al.   JOURNAL OF IMMUNOLOGY

Adipose circadian rhythms: Translating cellular and animal studies to human physiology

(2011) Jonathan D. Johnston   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand

(2011) Laura A. Solt et al.   NATURE

What's new in our understanding of the role of adipokines in rheumatic diseases?

(2011) Rodolfo Gómez et al.   Nature Reviews Rheumatology

Shift work and chronic disease: the epidemiological evidence

(2011) X.-S. Wang et al.   OCCUPATIONAL MEDICINE-OXFORD

Peripheral CLOCK Regulates Target-Tissue Glucocorticoid Receptor Transcriptional Activity in a Circadian Fashion in Man

(2011) Evangelia Charmandari et al.   PLoS One

Circadian Clocks in Mouse and Human CD4+ T Cells

(2011) Thomas Bollinger et al.   PLoS One

The nuclear receptor REV-ERB  mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines

(2011) J. E. Gibbs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tuning the Mammalian Circadian Clock: Robust Synergy of Two Loops

(2011) Angela Relógio et al.   PLoS Computational Biology

Targeting pathophysiological rhythms: prednisone chronotherapy shows sustained efficacy in rheumatoid arthritis

(2010) F. Buttgereit et al.   ANNALS OF THE RHEUMATIC DISEASES

Melatonin: A pleiotropic molecule regulating inflammation

(2010) Flavia Radogna et al.   BIOCHEMICAL PHARMACOLOGY

A circadian clock in murine bone marrow-derived mast cells modulates IgE-dependent activation in vitro

(2010) Xiaojia Wang et al.   BRAIN BEHAVIOR AND IMMUNITY

PER2 Controls Lipid Metabolism by Direct Regulation of PPARγ

(2010) Benedetto Grimaldi et al.   Cell Metabolism

Control of Macrophage Activation and Function by PPARs

(2010) Ajay Chawla   CIRCULATION RESEARCH

Rosiglitazone reduces a wide range of proinflammatory profiles in synovial fibroblast SW982 under spheroid culture

(2010) Jin Sook Song et al.   IMMUNOLOGY LETTERS

Dysregulation of Inflammatory Responses by Chronic Circadian Disruption

(2010) O. Castanon-Cervantes et al.   JOURNAL OF IMMUNOLOGY

A circadian-regulated gene, Nocturnin, promotes adipogenesis by stimulating PPAR-  nuclear translocation

(2010) M. Kawai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian dysfunction in disease

(2010) David A. Bechtold et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell–intrinsic fashion and suppresses CNS autoimmunity

(2009) Luisa Klotz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mammalian Clock Gene Cryptochrome Regulates Arthritis via Proinflammatory Cytokine TNF- 

(2009) A. Hashiramoto et al.   JOURNAL OF IMMUNOLOGY

Melatonin inhibits human fibroblast-like synoviocyte proliferation via extracellular signal-regulated protein kinase/P21CIP1/P27KIP1pathways

(2009) Seong-Su Nah et al.   JOURNAL OF PINEAL RESEARCH

The nuclear receptor RORα exerts a bi-directional regulation of IL-6 in resting and reactive astrocytes

(2009) Nathalie Journiac et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A circadian clock in macrophages controls inflammatory immune responses

(2009) Maren Keller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficacy of modified-release versus standard prednisone to reduce duration of morning stiffness of the joints in rheumatoid arthritis (CAPRA-1): a double-blind, randomised controlled trial

(2008) Frank Buttgereit et al.   LANCET