Article
Multidisciplinary Sciences
Marek Asman, Joanna Witecka, Jan Korbecki, Krzysztof Solarz
Summary: Ixodes ricinus is the main vector in Europe for Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum, and Babesia microti. A study conducted in Wolinski National Park showed a high potential human risk of exposure to tick-borne infection with Babesia microti, and low risks of infection with Borrelia garinii and Anaplasma phagocytophilum in the area.
SCIENTIFIC REPORTS
(2021)
Article
Immunology
Keith J. Price, Christine B. Graham, Bryn J. Witmier, Holly A. Chapman, Brooke L. Coder, Christian N. Boyer, Erik Foster, Sarah E. Maes, Ying Bai, Rebecca J. Eisen, Andrew D. Kyle
Summary: Ticks of Haemaphysalis longicornis collected from southeastern Pennsylvania were tested for pathogens, with 1 adult female testing positive for Borrelia burgdorferi sensu stricto, resulting in an infection rate of 0.4%. It is crucial to continue monitoring this invasive tick species to assess its impact on public health.
EMERGING INFECTIOUS DISEASES
(2021)
Article
Veterinary Sciences
Lauriane Duplaix, Victoria Wagner, Salima Gasmi, L. Robbin Lindsay, Antonia Dibernardo, Karine Thivierge, Christopher Fernandez-Prada, Julie Arsenault
Summary: A study conducted in Quebec from 2010 to 2017 revealed that cats and dogs are at risk of exposure to blacklegged ticks infected with Borrelia burgdorferi and Anaplasma phagocytophilum. The majority of ticks collected were adult females and partially engorged, with a higher prevalence of infections with B. burgdorferi and A. phagocytophilum.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Microbiology
Onur Ceylan, Benedicto Byamukama, Ceylan Ceylan, Eloiza May Galon, Mingming Liu, Tatsunori Masatani, Xuenan Xuan, Ferda Sevinc
Summary: The study revealed a high molecular prevalence of tick-borne pathogens (TBPs) in small ruminants in Turkey, with significant infections of Babesia ovis, Anaplasma ovis, Theileria ovis, and Anaplasma phagocytophilum. Co-infections of these pathogens were also detected, highlighting the importance of continuous screening and control measures to prevent diseases caused by tick-borne protozoan and rickettsial agents in Turkey.
Article
Infectious Diseases
Giovanni Sgroi, Roberta Iatta, Vincenzo Veneziano, Marcos Antonio Bezerra-Santos, Paulina Lesiczka, Kristyna Hrazdilova, Giada Annoscia, Nicola D'Alessio, Maryna Golovchenko, Natalie Rudenko, David Modry, Domenico Otranto
Summary: This study investigated the prevalence and distribution of tick-borne pathogens and Leishmania infantum in red foxes in Italy, revealing that the majority of foxes tested positive for at least one pathogen, with Hepatozoon canis being the most prevalent. It underlined the importance of monitoring these carnivores due to their contact with dogs and humans.
TICKS AND TICK-BORNE DISEASES
(2021)
Article
Biotechnology & Applied Microbiology
Ran Duan, Dongyue Lv, Rong Fan, Guoming Fu, Hui Mu, Jinxiao Xi, Xinmin Lu, Hua Chun, Jun Hua, Zhaokai He, Shuai Qin, Yanyan Huang, Meng Xiao, Jinchuan Yang, Huaiqi Jing, Xin Wang
Summary: In this study, A. phagocytophilum was identified for the first time in Marmota himalayana, a predominant Yersinia pestis host. The research provides initial evidence for M. himalayana being a reservoir for A. phagocytophilum, and indicates that marmots may be more vulnerable to plague in the presence of A. phagocytophilum. Humans are at risk for co-infection with both pathogens by exposure to such marmots.
Article
Microbiology
Tal Azagi, B. J. A. Hoeve-Bakker, Mark Jonker, Jeroen H. Roelfsema, Hein Sprong, Karen Kerkhof
Summary: This study evaluated the analytical specificity, sensitivity, and robustness of qPCR assays for detecting tick-borne pathogens in human samples. The results showed that the qPCRs performed well and were potentially suitable for human diagnostics. However, further clinical validation and independent confirmation are needed.
Article
Public, Environmental & Occupational Health
Thomas F. Rounsville, Griffin M. Dill, Ann M. Bryant, Claudia C. Desjardins, James F. Dill
Summary: This study provides an updated distribution of the blacklegged tick in Maine and reports the infection and coinfection prevalence of Borrelia burgdorferi, Anaplasma phagocytophilum, and Babesia microti within the state's tick population. Adult blacklegged ticks had higher infection rates compared to nymphs, while prevalence of Babesia microti was similar between adults and nymphs.
VECTOR-BORNE AND ZOONOTIC DISEASES
(2021)
Article
Parasitology
Hans-Peter Fuehrer, Ilona Soukup, Bita Shahi-Barogh, Walter Glawischnig
Summary: The importance of vectors and vector-borne diseases is increasing globally, but VBPs were not detected in alpine marmots' blood samples in the Alps region, indicating a possible lack of competent vectors in the area.
PARASITOLOGY RESEARCH
(2021)
Article
Microbiology
Min-Goo Seo, Haeseung Lee, Badriah Alkathiri, KyuSung Ahn, Seung-Hun Lee, SungShik Shin, Seulgi Bae, Kyoo-Tae Kim, Min Jang, Sang-Kwon Lee, Yun Sang Cho, Kyung-Yeon Eo, Oh-Deog Kwon, Dongmi Kwak
Summary: The present study aimed to investigate the dominant tick populations and identify the pathogenic agents of anaplasmosis in ticks from Gyeongsang, Republic of Korea. A total of 3825 questing ticks were collected from 12 sites near animal farms in Gyeongsang. Molecular genomic analysis was conducted to detect Anaplasma genes in the collected ticks. The most prevalent tick species were Haemaphysalis longicornis, Haemaphysalis sp., Haemaphysalis flava, Ixodes nipponensis, and Amblyomma testudinarium in that order. The infection rates of Anaplasma species varied, with A. phagocytophilum being the most common. The findings of this study provide valuable information for future research on tick-borne diseases.
Article
Microbiology
Nicholas Johnson, Megan Golding, Laurence Paul Phipps
Summary: In the UK, deer serve as a major vertebrate host for the hard tick Ixodes ricinus, potentially contributing to the persistence of tick-borne pathogens. Research revealed the presence of Babesia spp. and Anaplasma phagocytophilum in some red deer, with evidence of co-infection in certain individuals.
Article
Infectious Diseases
Aine Lehane, Sarah E. Maes, Christine B. Graham, Emma Jones, Mark Delorey, Rebecca J. Eisen
Summary: The geographic distributions of medically important ticks and tick-borne pathogens in the United States are expanding, leading to an increase in the burden of tick-borne diseases and a growing risk of coinfections. The study found that Borrelia burgdorferi s.s. was the most prevalent and widespread pathogen, and co-infections with this pathogen and others were most common in the Northeast region.
TICKS AND TICK-BORNE DISEASES
(2021)
Article
Agriculture, Dairy & Animal Science
Luca Villa, Alessia Libera Gazzonis, Carolina Allievi, Claudia De Maria, Maria Flaminia Persichetti, Giulia Caracappa, Sergio Aurelio Zanzani, Maria Teresa Manfredi
Summary: This study investigated the seroprevalence of three tick-borne pathogens in Italian horses and highlighted the importance of tick control. The study found that tick-borne diseases in horses are an emergent problem worldwide, with climate and ecological changes as well as horse movements between countries playing important roles in their spread.
Article
Ecology
Ryan T. Larson, Gebbiena M. Bron, Xia Lee, Tela E. Zembsch, Patricia N. Siy, Susan M. Paskewitz
Summary: The study found that woodland deer mice are important reservoirs of tick-borne pathogens in the Midwest, playing a crucial role in the maintenance of pathogen cycles. Compared to white-footed mice, woodland deer mice were more likely to be infected and had higher infection rates, potentially leading to more transmission of tick-borne pathogens.
Article
Multidisciplinary Sciences
Anna Kocon, Marek Asman, Magdalena Nowak-Chmura, Joanna Witecka, Grzegorz Raczka
Summary: The study compared the risk of exposure to ticks and tick-borne infections in dogs and cats in recreational and urbanized areas in Lesser Poland and Silesian Provinces. The findings suggest that these animals play an important role in the circulation of tick-borne pathogens in nature.
SCIENTIFIC REPORTS
(2022)
Article
Infectious Diseases
Jia-Fu Jiang, Rui-Ruo Jiang, Qiao-Cheng Chang, Yuan-Chun Zheng, Bao-Gui Jiang, Yi Sun, Na Jia, Ran Wei, Hong-Bo Liu, Qiu-Bo Huo, Hong Wang, Michael E. von Fricken, Wu-Chun Cao
PLOS NEGLECTED TROPICAL DISEASES
(2018)
Article
Parasitology
Chun-Hong Du, Yi Sun, Rong-Man Xu, ZongTi Shao
ACTA PARASITOLOGICA
(2018)
Article
Medicine, General & Internal
Na Jia, Hong-Bo Liu, Xue-Bing Ni, Lesley Bell-Sakyi, Yuan-Chun Zheng, Ju-Liang Song, Jie Li, Bao-Gui Jiang, Qian Wang, Yi Sun, Ran Wei, Ting-Ting Yuan, Luo-Yuan Xia, Yan-Li Chu, Wei Wei, Lian-Feng Li, Jin-Ling Ye, Qing-Yu Lv, Xiao-Ming Cui, Yi Guan, Yi-Gang Tong, Jia-Fu Jiang, Tommy Tsan-Yuk Lam, Wu-Chun Cao
Article
Ecology
Yi Sun, Rongman Xu, Zengjia Liu, Mingyu Wu, Tong Qin
INTERNATIONAL JOURNAL FOR PARASITOLOGY-PARASITES AND WILDLIFE
(2019)
Article
Infectious Diseases
Yuan-Yuan Hu, Lu Zhuang, Kun Liu, Yi Sun, Ke Dai, Xiao-Ai Zhang, Pan-He Zhang, Zhi-Chun Feng, Hao Li, Wei Liu
PLOS NEGLECTED TROPICAL DISEASES
(2020)
Article
Biochemistry & Molecular Biology
Na Jia, Jinfeng Wang, Wenqiang Shi, Lifeng Du, Yi Sun, Wei Zhan, Jia-Fu Jiang, Qian Wang, Bing Zhang, Peifeng Ji, Lesley Bell-Sakyi, Xiao-Ming Cui, Ting-Ting Yuan, Bao-Gui Jiang, Wei-Fei Yang, Tommy Tsan-Yuk Lam, Qiao-Cheng Chang, Shu-Jun Ding, Xian-Jun Wang, Jin-Guo Zhu, Xiang-Dong Ruan, Lin Zhao, Jia-Te Wei, Run-Ze Ye, Teng Cheng Que, Chun-Hong Du, Yu-Hao Zhou, Jing Xia Cheng, Pei-Fang Dai, Wen-Bin Guo, Xiao-Hu Han, En-Jiong Huang, Lian-Feng Li, Wei Wei, Yu-Chi Gao, Jing-Ze Liu, Hong-Ze Shao, Xin Wang, Chong-Cai Wang, Tian-Ci Yang, Qiu-Bo Huo, Wei Li, Hai-Ying Chen, Shen-En Chen, Ling-Guo Zhou, Xue-Bing Ni, Jun-Hua Tian, Yue Sheng, Tao Liu, Yu-Sheng Pan, Luo-Yuan Xia, Jie Li, Fangqing Zhao, Wu-Chun Cao
Article
Microbiology
Jun Jiao, Jianing Zhang, Peisheng He, Xuan OuYang, Yonghui Yu, Bohai Wen, Yi Sun, Qinghong Yuan, Xiaolu Xiong
Summary: This study detected various tick-borne pathogens (TBPs) in Rh. microplus in Yunnan, China, including Ca. Rickettsia jingxinensis, Anaplasma marginale, Coxiella burnetii, and Coxiella-like endosymbiont (CLE). It also reported for the first time that C. burnetii had been found in Rh. microplus in China. MLVA analysis distinguished the C. burnetii detected in Yunnan into MLVA genotype 1, indicating a potential public health threat posed by C. burnetii in Rh. microplus in Yunnan.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Microbiology
Liang-Jing Li, Nian-Zhi Ning, Yuan-Chun Zheng, Yan-Li Chu, Xiao-Ming Cui, Ming-Zhu Zhang, Wen-Bin Guo, Ran Wei, Hong-Bo Liu, Yi Sun, Jin-Ling Ye, Bao-Gui Jiang, Ting-Ting Yuan, Jie Li, Cai Bian, Lesley Bell-Sakyi, Hui Wang, Jia-Fu Jiang, Ju-Liang Song, Wu-Chun Cao, Tommy Tsan-Yuk Lam, Xue-Bing Ni, Na Jia
Summary: Ticks have co-evolved with pathogens, resulting in mutual adaptation. This study analyzed the virome and gene expression of ticks at different stages of blood-feeding, revealing the significance of tick virome surveillance and the role of reactive oxygen species in modulating the microbiome during blood-feeding. The study also identified potential mammalian hosts for ticks, emphasizing their public health importance.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Parasitology
Xin-yan Lu, Quan-fu Zhang, Dan-dan Jiang, Tao Wang, Yi Sun, Chun-hong Du, Lei Zhang, Xing Yang
Summary: This study sequenced and analyzed the mitochondrial genome of Haemaphysalis kolonini, comparing it with previous research and providing new insights into the phylogenetic relationship of this species.
PARASITOLOGY RESEARCH
(2022)
Article
Microbiology
Zhihai He, Baogui Jiang, Lin Huang, Zongti Shao, Yun Zhang, Yuqiong Li, Ennian Pu, Xingde Duan, Hang Jiang, Jian Wang, Mingguo Yao, Fan Wang, Shuangshuang Bie, Michael E. von Fricken, Yi Sun, Yi Dong, Jiafu Jiang, Chunhong Du
Summary: This study conducted a comprehensive investigation of Borrelia burgdorferi sensu lato (BBSL) in reservoirs and vectors in Yunnan Province, China. The results revealed a wide distribution of BBSL and multiple endemic genospecies, highlighting the need for expanded surveillance efforts for human in southwestern China.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Lian-Feng Li, Ming-Zhu Zhang, Jin-Guo Zhu, Xiao-Ming Cui, Chao-Fu Zhang, Ting-Yong Niu, Jie Li, Yi Sun, Wei- Wei, Hong-Bo Liu, Ting-Ting Yuan, Ran Wei, Qian Wang, Luo-Yuan Xia, Lin Zhao, Bell-Sakyi Lesley, Bao-Gui Jiang, Jia-Fu Jiang, Jongejan Frans, Na Jia, Wu-Chun Cao
Summary: Our study reveals that Jingmen tick virus (JMTV) cannot replicate and transmit in the tick species, Dermacentor silvarum (D. silvarum), suggesting that D. silvarum is not susceptible to JMTV infection and unlikely to carry and transmit JMTV.
VECTOR-BORNE AND ZOONOTIC DISEASES
(2022)
Article
Microbiology
Yu-Sheng Pan, Xiao-Ming Cui, Li-Feng Du, Luo-Yuan Xia, Chun-Hong Du, Lesley Bell-Sakyi, Ming-Zhu Zhang, Dai-Yun Zhu, Yi Dong, Wei Wei, Lin Zhao, Yi Sun, Qing-Yu Lv, Run-Ze Ye, Zhi-Hai He, Qian Wang, Liang-Jing Li, Ming-Guo Yao, Tao Xiong, Jia-Fu Jiang, Wu-Chun Cao, Na Jia
Summary: This study identified two Rickettsia species in Haemaphysalis montgomeryi ticks and confirmed co-infection in 25.6% of field-collected ticks. Furthermore, the study demonstrated that one species of Rickettsia overwhelmed the other in cell culture infection models, indicating potential differences in their interactions with the host.
MICROBIOLOGY SPECTRUM
(2022)
Article
Microbiology
Xue-Bing Ni, Xiao-Ming Cui, Jin-Yue Liu, Run-Ze Ye, Yu-Qian Wu, Jia-Fu Jiang, Yi Sun, Qian Wang, Marcus Ho-Hin Shum, Qiao-Cheng Chang, Lin Zhao, Xiao-Hu Han, Ke Ma, Shi-Jing Shen, Ming-Zhu Zhang, Wen-Bin Guo, Jin-Guo Zhu, Lin Zhan, Liang-Jing Li, Shu-Jun Ding, Dai-Yun Zhu, Jie Zhang, Luo-Yuan Xia, Xiang-Yong Oong, Xiang-Dong Ruan, Hong-Ze Shao, Teng-Cheng Que, Guang-Yuan Liu, Chun-Hong Du, En-Jiong Huang, Xin Wang, Li-Feng Du, Chong-Cai Wang, Wen-Qiang Shi, Yu-Sheng Pan, Yu-Hao Zhou, Jiang-Li Qu, Jiang Ma, Cai-Wei Gong, Qi-Qing Chen, Qian Qin, Tommy Tsan-Yuk Lam, Na Jia, Wu-Chun Cao
Summary: We sequenced the meta-transcriptomes of 31 different tick species in China and identified 724 RNA viruses with unique virome compositions. We found that tick-associated viruses exhibit extensive genome diversity and are more ancient than other arboviruses. Tick-specific viruses are often associated with a few tick species, while those that can infect vertebrates are found in a wider range of tick species. Our dataset provides valuable insights for further research on tick-associated viruses that are pathogenic to vertebrates.
NATURE MICROBIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Shan-Shan Wang, Jin-Yue Liu, Bao-Yu Wang, Wen-Jing Wang, Xiao-Ming Cui, Jia-Fu Jiang, Yi Sun, Wen-Bin Guo, Yu-Sheng Pan, Yu-Hao Zhou, Zhe-Tao Lin, Bao-Gui Jiang, Lin Zhao, Wu-Chun Cao
Summary: The increasing incidence and range expansion of tick-borne diseases have become a global threat to human and animal health due to climate and socioeconomic changes. This study summarized the distribution, hosts, and pathogens of I. persulcatus, and predicted its suitable habitats worldwide.
Article
Infectious Diseases
Lei Huang, Yi Sun, Dan-Dan Huo, Ming Xu, Luo-Yuan Xia, Ning Yang, Wei Hong, Lin Huang, Wei-Min Nie, Ru-He Liao, Ming-Zhu Zhang, Dai-Yun Zhu, Yan Li, He-Cheng Ma, Xin Zhang, Yong-Gang Li, Xin-An Huang, Jing-Yuan Wang, Wu-Chun Cao, Fu-Sheng Wang, Jia-Fu Jiang
Summary: This study developed a novel treatment regimen using doxycycline monotherapy for a patient with severe Babesia venatorum infection as an alternative therapeutic medication. The patient recovered rapidly and no side effects or sequelae were observed during the treatment. This provides an optional medical intervention for human babesiosis.
INFECTIOUS DISEASES OF POVERTY
(2023)
Article
Infectious Diseases
Harold Salant, Yaarit Nachum-Biala, Doni Zivotofsky, Tsachi Even Tzur, Gad Baneth
Summary: This study describes the presentation, clinical signs, parasitemia levels, laboratory findings and treatment of dogs infected with B. negevi. Treatment with imidocarb dipropionate was helpful for recovery from clinical disease but did not facilitate parasite elimination, and it is therefore recommended to treat canine B. negevi infection with the combination of atovaquone and azithromycin.
TICKS AND TICK-BORNE DISEASES
(2024)
Article
Infectious Diseases
Gervillien Arnold Malonga, Almoustapha Issiaka Maiga, Dimitry Moudiongui Mboungou Malanda, Mahamadou Saliou, Juth ece Private Malanda-Kiminou, Oumar Dolo, Anicet Luc Magloire Boumba, Alhassane Ba, Robert Murphy, Jean Felix Peko, Anne-Genevieve Marcelin, Vincent Calvez, Stephane Marot
Summary: A serological survey in sub-urban areas of the capital cities of Congo and Mali reveals human contact with Crimean-Congo hemorrhagic fever virus (CCHFV) associated with previously described CCHFV risk factors.
TICKS AND TICK-BORNE DISEASES
(2024)
Article
Infectious Diseases
Aleksander Wymazal, Sabina Nowak, Robert W. Myslajek, Anna Bajer, Renata Welc-Faleciak, Maciej Szewczyk, Iga Kwiatkowska, Kinga M. Stepniak, Michal Figura, Agnieszka Kloch
Summary: The wolf population in Central and Eastern Europe has been increasing, but their frequent contacts with humans make them a potential zoonotic reservoir. This study found a high prevalence of tick-borne pathogens in free-ranging wolves from Poland.
TICKS AND TICK-BORNE DISEASES
(2024)
Article
Infectious Diseases
Nannet D. Fabri, Hans Heesterbeek, Joris P. G. M. Cromsigt, Frauke Ecke, Hein Sprong, Lonneke Nijhuis, Tim R. Hofmeester, Nienke Hartemink
Summary: In many parts of the northern hemisphere, different species of deer, small mammals, and birds coexist and their composition can strongly influence the outbreak potential of tick-borne pathogens. This study investigates how the abundance and composition of vertebrate communities affect the basic reproduction number R0 of tick-borne pathogens, and shows that species composition plays a substantial role in the outbreak potential of tick-borne diseases.
TICKS AND TICK-BORNE DISEASES
(2024)
Article
Infectious Diseases
Lynn M. Osikowicz, Maria R. Rizzo, Andrias Hojgaard, Sarah E. Maes, Rebecca J. Eisen
Summary: This article describes the prevalence and diversity of Lyme disease in the United States. By using different detection methods, the authors found various species of spirochetes present in specific tick species, revealing the potential transmission of pathogens among ticks.
TICKS AND TICK-BORNE DISEASES
(2024)
Review
Infectious Diseases
El-Sayed El-Alfy, Ibrahim Abbas, Somaya Saleh, Rana Elseadawy, Ragab M. Fereig, Mohamed Abdo Rizk, Xuenan Xuan
Summary: Published data on tick-borne pathogens in camels worldwide have been collected, providing an overview of their global prevalence and species diversity. Evidence of natural infection of camels with certain tick-borne pathogens is limited, particularly because most of the camels were considered healthy at the time of sampling. More research is needed to understand the role of camels in maintaining and transmitting these pathogens.
TICKS AND TICK-BORNE DISEASES
(2024)
Article
Infectious Diseases
Saana Sipari, Mikko Kiljunen, Minna Nylund, Eva R. Kallio
Summary: This study introduces a stable isotope analysis method to directly identify tick breeding hosts by sampling field collected larvae. The results show that stable isotope signatures can reflect the diet of the breeding host of the mother tick.
TICKS AND TICK-BORNE DISEASES
(2024)
