The IKK Kinases: Operators of Antiviral Signaling

Receptor-Interacting Protein Homotypic Interaction Motif-Dependent Control of NF- B Activation via the DNA-Dependent Activator of IFN Regulatory Factors

(2014) W. J. Kaiser et al.   JOURNAL OF IMMUNOLOGY

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5

(2009) Xiaojun Li et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-κB

(2009) Manuele Rebsamen et al.   EMBO REPORTS

Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

(2009) Martin Schlee et al.   IMMUNITY

NEMO-binding Domains of Both IKKα and IKKβ Regulate IκB Kinase Complex Assembly and Classical NF-κB Activation

(2009) Laura A. Solt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TANK-Binding Kinase-1 Plays an Important Role during In Vitro and In Vivo Type I IFN Responses to DNA Virus Infections

(2009) A. K. Miyahira et al.   JOURNAL OF IMMUNOLOGY

Ubiquitin-Regulated Recruitment of I B Kinase   to the MAVS Interferon Signaling Adapter

(2009) S. Paz et al.   MOLECULAR AND CELLULAR BIOLOGY

Phosphorylation of the Tumor Suppressor CYLD by the Breast Cancer Oncogene IKKɛ Promotes Cell Transformation

(2009) Jessica E. Hutti et al.   MOLECULAR CELL

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

(2009) Teresa Fernandes-Alnemri et al.   NATURE

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA

(2009) T. L. Roberts et al.   SCIENCE

The role of mitochondria in cellular defense against microbial infection

(2009) Damien Arnoult et al.   SEMINARS IN IMMUNOLOGY

The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response

(2008) Constantin S Friedman et al.   EMBO REPORTS

TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway

(2008) Marie-Cécile Michallet et al.   IMMUNITY

Phosphorylation of IRF-3 on Ser 339 Generates a Hyperactive Form of IRF-3 through Regulation of Dimerization and CBP Association

(2008) J.-F. Clement et al.   JOURNAL OF VIROLOGY

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

(2008) Daniel A. Muruve et al.   NATURE

NLRX1 is a regulator of mitochondrial antiviral immunity

(2008) Chris B. Moore et al.   NATURE

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE

Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2

(2008) Tatsukata Kawagoe et al.   NATURE IMMUNOLOGY

Are the IKKs and IKK-related kinases TBK1 and IKK-ɛ similarly activated?

(2008) Tieu-Lan Chau et al.   TRENDS IN BIOCHEMICAL SCIENCES

Differential regulation of IKKα-mediated activation of IRF3/7 by NIK

(2007) Rui-Peng Wang et al.   MOLECULAR IMMUNOLOGY