The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution

Rabconnectin-3a Regulates Vesicle Endocytosis and Canonical Wnt Signaling in Zebrafish Neural Crest Migration

(2014) Adam M. Tuttle et al.   PLOS BIOLOGY

The thioredoxin antioxidant system

(2013) Jun Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Differential expression of liver fluke β-tubulin isotypes at selected life cycle stages

(2013) Marc-Aurel Fuchs et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Correction: Conditionally Immortalized Mouse Embryonic Fibroblasts Retain Proliferative Activity without Compromising Multipotent Differentiation Potential

(2013) Enyi Huang et al.   PLoS One

Immunomodulatory molecules of Fasciola hepatica: Candidates for both vaccine and immunotherapeutic development

(2013) John P. Dalton et al.   VETERINARY PARASITOLOGY

Reference-Free Population Genomics from Next-Generation Transcriptome Data and the Vertebrate–Invertebrate Gap

(2013) Philippe Gayral et al.   PLoS Genetics

Dissecting the Active Site of the Collagenolytic Cathepsin L3 Protease of the Invasive Stage of Fasciola hepatica

(2013) Ileana Corvo et al.   PLoS Neglected Tropical Diseases

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

REAPR: a universal tool for genome assembly evaluation

(2013) Martin Hunt et al.   GENOME BIOLOGY

Thioredoxin Glutathione Reductase-Dependent Redox Networks in Platyhelminth Parasites

(2012) David L. Williams et al.   ANTIOXIDANTS & REDOX SIGNALING

Early and Late Peritoneal and Hepatic Changes in Goats Immunized with Recombinant Cathepsin L1 and Infected with Fasciola hepatica

(2012) R. Zafra et al.   JOURNAL OF COMPARATIVE PATHOLOGY

Proteomics and in Silico Approaches To Extend Understanding of the Glutathione Transferase Superfamily of the Tropical Liver Fluke Fasciola gigantica

(2012) Russell M. Morphew et al.   JOURNAL OF PROTEOME RESEARCH

An amino acid substitution in Fasciola hepatica P-glycoprotein from triclabendazole-resistant and triclabendazole-susceptible populations

(2012) Richard Wilkinson et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Whole-genome sequence of Schistosoma haematobium

(2012) Neil D Young et al.   NATURE GENETICS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

(2012) Davis J. McCarthy et al.   NUCLEIC ACIDS RESEARCH

Evolution of sex chromosomes ZW of Schistosoma mansoni inferred from chromosome paint and BAC mapping analyses

(2012) Hirohisa Hirai et al.   PARASITOLOGY INTERNATIONAL

Identification of a field isolate of Fasciola hepatica resistant to albendazole and susceptible to triclabendazole

(2012) Rodrigo Sanabria et al.   VETERINARY PARASITOLOGY

Fasciola hepatica is associated with the failure to detect bovine tuberculosis in dairy cattle

(2012) Jen Claridge et al.   Nature Communications

A Systematically Improved High Quality Genome and Transcriptome of the Human Blood Fluke Schistosoma mansoni

(2012) Anna V. Protasio et al.   PLoS Neglected Tropical Diseases

A recombinant thioredoxin-glutathione reductase from Fasciola hepatica induces a protective response in rabbits

(2011) Gabriela Maggioli et al.   EXPERIMENTAL PARASITOLOGY

Global burden of human food-borne trematodiasis: a systematic review and meta-analysis

(2011) Thomas Fürst et al.   LANCET INFECTIOUS DISEASES

Fasciola hepatica virulence-associated cysteine peptidases: a systems biology perspective

(2011) Paul McVeigh et al.   MICROBES AND INFECTION

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Producing parasitic helminth reference and draft genomes at the Wellcome Trust Sanger Institute

(2011) N. HOLROYD et al.   PARASITE IMMUNOLOGY

Inhibition of triclabendazole metabolism in vitro by ketoconazole increases disruption to the tegument of a triclabendazole-resistant isolate of Fasciola hepatica

(2011) C. Devine et al.   PARASITOLOGY RESEARCH

Potentiation of triclabendazole action in vivo against a triclabendazole-resistant isolate of Fasciola hepatica following its co-administration with the metabolic inhibitor, ketoconazole

(2011) C. Devine et al.   VETERINARY PARASITOLOGY

Parasite neuropeptide biology: Seeding rational drug target selection?

(2011) Paul McVeigh et al.   International Journal for Parasitology-Drugs and Drug Resistance

Scaffolding pre-assembled contigs using SSPACE

(2010) Marten Boetzer et al.   BIOINFORMATICS

Benzimidazole resistance allele haplotype diversity in United Kingdom isolates of Teladorsagia circumcincta supports a hypothesis of multiple origins of resistance by recurrent mutation

(2010) Philip Skuce et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Peroxiredoxin: a central player in immune modulation

(2010) M. W. ROBINSON et al.   PARASITE IMMUNOLOGY

A Dual Platform Approach to Transcript Discovery for the Planarian Schmidtea Mediterranea to Establish RNAseq for Stem Cell and Regeneration Biology

(2010) Martin J. Blythe et al.   PLoS One

Elucidating the transcriptome of Fasciola hepatica — A key to fundamental and biotechnological discoveries for a neglected parasite

(2009) Neil D. Young et al.   BIOTECHNOLOGY ADVANCES

Food-Borne Trematodiases

(2009) J. Keiser et al.   CLINICAL MICROBIOLOGY REVIEWS

Major Secretory Antigens of the Helminth Fasciola hepatica Activate a Suppressive Dendritic Cell Phenotype That Attenuates Th17 Cells but Fails To Activate Th2 Immune Responses

(2009) D. J. Dowling et al.   INFECTION AND IMMUNITY

An Integrated Transcriptomics and Proteomics Analysis of the Secretome of the Helminth PathogenFasciola hepatica

(2009) Mark W. Robinson et al.   MOLECULAR & CELLULAR PROTEOMICS

A family of cathepsin F cysteine proteases of Clonorchis sinensis is the major secreted proteins that are expressed in the intestine of the parasite

(2009) Jung-Mi Kang et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The Schistosoma japonicum genome reveals features of host–parasite interplay

(2009)   NATURE

The genome of the blood fluke Schistosoma mansoni

(2009) Matthew Berriman et al.   NATURE

Zoonotic helminth infections with particular emphasis on fasciolosis and other trematodiases

(2009) M. W. Robinson et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Characterization and distribution of retrotransposons and simple sequence repeats in the bovine genome

(2009) D. L. Adelson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages

(2008) Sheila Donnelly et al.   FASEB JOURNAL

Inhibition of cytochrome P450 activity enhances the systemic availability of triclabendazole metabolites in sheep

(2008) G. VIRKEL et al.   JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Proteomics and Phylogenetic Analysis of the Cathepsin L Protease Family of the Helminth PathogenFasciola hepatica

(2008) Mark W. Robinson et al.   MOLECULAR & CELLULAR PROTEOMICS

Fasciola hepatica expresses multiple α- and β-tubulin isotypes

(2008) Louise A. Ryan et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The enigmatic asparaginyl endopeptidase of helminth parasites

(2008) John P. Dalton et al.   TRENDS IN PARASITOLOGY

The silencing of cysteine proteases in Fasciola hepatica newly excysted juveniles using RNA interference reduces gut penetration

(2007) L MCGONIGLE et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY