The Innate Immune System of the Perinatal Lung and Responses to Respiratory Syncytial Virus Infection

Pulmonary intravascular macrophages and lung health: What are we missing?

(2012) David Schneberger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Benefit and harm from immunity to respiratory syncytial virus

(2012) Maximillian S. Habibi et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Specific increase in local IL-17 production during recovery from primary RSV bronchiolitis

(2012) Tina E. Faber et al.   JOURNAL OF MEDICAL VIROLOGY

TLR2/MyD88/NF-κB Pathway, Reactive Oxygen Species, Potassium Efflux Activates NLRP3/ASC Inflammasome during Respiratory Syncytial Virus Infection

(2012) Jesus Segovia et al.   PLoS One

Stimulation of Immature Lung Macrophages with Intranasal Interferon Gamma in a Novel Neonatal Mouse Model of Respiratory Syncytial Virus Infection

(2012) Kerry M. Empey et al.   PLoS One

A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia

(2012) B. Button et al.   SCIENCE

Perinatal Lamb Model of Respiratory Syncytial Virus (RSV) Infection

(2012) Rachel J. Derscheid et al.   Viruses-Basel

Respiratory Syncytial Virus Fusion Protein-Induced Toll-Like Receptor 4 (TLR4) Signaling Is Inhibited by the TLR4 Antagonists Rhodobacter sphaeroides Lipopolysaccharide and Eritoran (E5564) and Requires Direct Interaction with MD-2

(2012) P. Rallabhandi et al.   mBio

Enhancement of Respiratory Mucosal Antiviral Defenses by the Oxidation of Iodide

(2011) Anthony J. Fischer et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Airway Epithelium: Soldier in the Fight against Respiratory Viruses

(2011) M. Vareille et al.   CLINICAL MICROBIOLOGY REVIEWS

Protein kinase PKR and RNA adenosine deaminase ADAR1: new roles for old players as modulators of the interferon response

(2011) Christian K Pfaller et al.   CURRENT OPINION IN IMMUNOLOGY

Neonatal lung immune responses show a shift of cytokines and transcription factors toward Th2 and a deficit in conventional and plasmacytoid dendritic cells

(2011) Xavier Roux et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Exogenous administration of vascular endothelial growth factor prior to human respiratory syncytial virus a2 infection reduces pulmonary pathology in neonatal lambs and alters epithelial innate immune responses

(2011) Alicia K. Olivier et al.   EXPERIMENTAL LUNG RESEARCH

Attenuated interleukin-8/leukocyte immunoresponse in preterm infants compared with term infants hospitalized with respiratory syncytial virus bronchiolitis: a pilot study

(2011) Dagnachew Assefa et al.   HUMAN IMMUNOLOGY

Ontogeny of the Immune Response in the Ovine Lung

(2011) Fatoumata B. Sow et al.   IMMUNOLOGICAL INVESTIGATIONS

SP-A1, SP-A2 and SP-D gene polymorphisms in severe acute respiratory syncytial infection in Chilean infants

(2011) Sandra Ampuero et al.   INFECTION GENETICS AND EVOLUTION

Multiple Functional Domains and Complexes of the Two Nonstructural Proteins of Human Respiratory Syncytial Virus Contribute to Interferon Suppression and Cellular Location

(2011) S. Swedan et al.   JOURNAL OF VIROLOGY

Identification of nucleolin as a cellular receptor for human respiratory syncytial virus

(2011) Farnoosh Tayyari et al.   NATURE MEDICINE

IL10 Family Member Genes IL19 and IL20 Are Associated With Recurrent Wheeze After Respiratory Syncytial Virus Bronchiolitis

(2011) Marieke J J Ermers et al.   PEDIATRIC RESEARCH

Primary Human mDC1, mDC2, and pDC Dendritic Cells Are Differentially Infected and Activated by Respiratory Syncytial Virus

(2011) Teresa R. Johnson et al.   PLoS One

Role of epithelial mucins during airway infection

(2011) Kwang Chul Kim   PULMONARY PHARMACOLOGY & THERAPEUTICS

Progress in understanding and controlling respiratory syncytial virus: Still crazy after all these years

(2011) Peter L. Collins et al.   VIRUS RESEARCH

Exposure to ethanol during the last trimester of pregnancy alters the maturation and immunity of the fetal lung

(2010) Tatjana Lazic et al.   ALCOHOL

Respiratory syncytial virus is associated with an inflammatory response in lungs and architectural remodeling of lung-draining lymph nodes of newborn lambs

(2010) Fatoumata B. Sow et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium

(2010) Peter G. Barlow et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Proteoglycans: Key Regulators of Pulmonary Inflammation and the Innate Immune Response to Lung Infection

(2010) Sean Gill et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

A critical review of the roles of host lactoferrin in immunity

(2010) Dominique Legrand et al.   BIOMETALS

Respiratory Virus-Induced TLR7 Activation Controls IL-17-Associated Increased Mucus via IL-23 Regulation

(2010) N. W. Lukacs et al.   JOURNAL OF IMMUNOLOGY

Respiratory Syncytial Virus F and G Proteins Induce Interleukin 1α, CC, and CXC Chemokine Responses by Normal Human Bronchoepithelial Cells

(2010) Christine M. Oshansky et al.   JOURNAL OF INFECTIOUS DISEASES

Human MxA Protein: An Interferon-Induced Dynamin-Like GTPase with Broad Antiviral Activity

(2010) Otto Haller et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The Oligoadenylate Synthetase Family: An Ancient Protein Family with Multiple Antiviral Activities

(2010) Helle Kristiansen et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Transforming Growth Factor Beta Is a Major Regulator of Human Neonatal Immune Responses following Respiratory Syncytial Virus Infection

(2010) N. J. Thornburg et al.   JOURNAL OF VIROLOGY

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

(2010) Harish Nair et al.   LANCET

Changes in helper lymphocyte chemokine receptor expression and elevation of IP-10 during acute respiratory syncytial virus infection in infants

(2010) Michael F. E. Roe et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Toll-like receptor 4 Asp299Gly polymorphism in respiratory syncytial virus epidemics

(2010) Johan Löfgren et al.   PEDIATRIC PULMONOLOGY

TLR4 Asp299Gly and Thr399Ile Polymorphisms: No Impact on Human Immune Responsiveness to LPS or Respiratory Syncytial Virus

(2010) Renée N. Douville et al.   PLoS One

Differential expression of cytokine transcripts in neonatal and adult ovine alveolar macrophages in response to respiratory syncytial virus or toll-like receptor ligation

(2010) Sasha J. Fach et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Respiratory syncytial virus infection alters surfactant protein A expression in human pulmonary epithelial cells by reducing translation efficiency

(2009) Shirley R. Bruce et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Phenotype and function of neonatal DC

(2009) Fabienne Willems et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human respiratory syncytial virus A2 strain replicates and induces innate immune responses by respiratory epithelia of neonatal lambs

(2009) Alicia Olivier et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

The Unexpected Pleiotropic Activities of RANTES

(2009) J. A. Levy   JOURNAL OF IMMUNOLOGY

Antiviral Activity of Innate Immune Protein ISG15

(2009) Ronald N. Harty et al.   Journal of Innate Immunity

Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages

(2009) Hsin-Ni Li et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Surfactant Protein A2 Polymorphisms and Disease Severity in a Respiratory Syncytial Virus-Infected Population

(2009) Chadi M. El Saleeby et al.   JOURNAL OF PEDIATRICS

RANTES Promoter Gene Polymorphisms and Susceptibility to Severe Respiratory Syncytial Virus-Induced Bronchiolitis

(2009) Virginia Amanatidou et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Impaired Immune Response in Severe Human Lower Tract Respiratory Infection by Respiratory Syncytial Virus

(2009) Carmen L. Larrañaga et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Role of Human β-Defensin-2 during Tumor Necrosis Factor-α/NF-κB-mediated Innate Antiviral Response against Human Respiratory Syncytial Virus

(2008) Srikanth Kota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Respiratory Syncytial Virus Activates Innate Immunity through Toll-Like Receptor 2

(2008) M. R. Murawski et al.   JOURNAL OF VIROLOGY

Biomedical applications of sheep models: from asthma to vaccines

(2008) Jean-Pierre Y. Scheerlinck et al.   TRENDS IN BIOTECHNOLOGY