Article
Fisheries
Hee-Jae Choi, Ji-Hoon Lee, Da-Yeon Choi, Ji-Eun Lee, Saran Hori, Kyu Seok Cho, Jun-Hwan Kim, Seong Hee Choi, Yue Jai Kang
Summary: This study found that cephalexin has good therapeutic effects against Streptococcus parauberis infected olive flounders, with no significant toxicity and a rapid metabolism rate.
AQUACULTURE RESEARCH
(2023)
Article
Agriculture, Dairy & Animal Science
Min-Gi Kim, Buddhi E. Gunathilaka, Jaehyeong Shin, Hyunwoon Lim, Jongho Lim, Sungho Lee, Youjeong Kim, Joon-Bum Jeong, Seung-Cheol Ji, Kyeong-Jun Lee
Summary: This study suggests that dietary supplementation of Bacillus sp. SW1-1 can enhance the activity of antioxidant enzymes, innate immunity, digestibility, and disease resistance in olive flounder.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Analytical
Thenmozhi Rajarathinam, Seonghye Kim, Dinakaran Thirumalai, Sujin Lee, Minho Kwon, Hyun-jong Paik, Suhkmann Kim, Seung-Cheol Chang
Summary: The study developed a disposable amperometric biosensor for early diagnosis of bacterial infections in farmed olive flounder, utilizing Prussian blue nanozyme and lactate oxidase immobilized on copolymer-reduced graphene oxide. The biosensor showed high sensitivity, dynamic linear response range, and stability, providing a reliable method for rapid detection of infections in fish farms.
Article
Fisheries
Jeong In Yang, Ki Hong Kim
Summary: This study demonstrates that fusion of S. iniae alpha-enolase with IMX313 significantly enhances antibody titers and protective efficacy in olive flounder immunization. Fusion of antigens with IMX313 can effectively enhance the protective efficacy of subunit vaccines in olive flounder.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Fisheries
Kun Yang, Xueshu Zhang, Zengyu Liu, Weiqun Lu
Summary: In animals, personalities have been found to be linked to behavioral traits, health and disease susceptibility, and welfare. This study examines the performance differences of flounder offspring with different personalities (OFDP). The offspring of bold individuals (OB) were found to be heavier and have higher survival rates compared to the offspring of shy individuals (OS). The study also analyzes the variability of microsatellites and their relationship with OFDP, and finds that certain microsatellite loci are correlated with growth, heat tolerance, and disease resistance. These findings contribute to olive flounder aquaculture and provide insights for fish personality selective breeding.
Article
Food Science & Technology
D. P. Nagahawatta, N. M. Liyanage, Thilina U. Jayawardena, H. H. A. C. K. Jayawardhana, Jae-Young Oh, K. K. Asanka Sanjeewa, Sang In Kang, You-Jin Jeon
Summary: The study found that digested flounder meat has the potential to promote skeletal muscle growth and can be used as a functional food ingredient.
Article
Fisheries
E. H. T. Thulshan Jayathilaka, S. L. Edirisinghe, Chulhong Oh, Chamilani Nikapitiya, Mahanama De Zoysa
Summary: This study investigates the isolation, physicochemical and molecular characteristics, toxicity, wound healing, and regeneration properties of exosomes derived from olive flounder. The study reveals the presence of specific surface markers and differentially expressed miRNAs in these exosomes, which are involved in various physiological and immunological functions, including wound healing and fin regeneration. The results demonstrate the potential therapeutic applications of these exosomes in wound healing.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Md Tawheed Hasan, Won Je Jang, Bong-Joo Lee, Sang Woo Hur, Sang Gu Lim, Kang Woong Kim, Hyon-Sob Han, Eun-Woo Lee, Sungchul C. Bai, In-Soo Kong
Summary: In this experiment, different ratios of Bacillus sp. SJ-10 and Lactobacillus plantarum KCCM 11322 mixtures were tested in olive flounder. The 3:1 ratio of the mixture showed improved growth, increased immune response, and enhanced resistance to Streptococcus iniae infection compared to the control and single probiotic diets.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2021)
Article
Fisheries
W. K. M. Omeka, D. S. Liyanage, Sukkyoung Lee, Chaehyeon Lim, Hyerim Yang, W. M. Gayashani Sandamalika, H. M. V. Udayantha, Gaeun Kim, Subothini Ganeshalingam, Taehyug Jeong, Seong-Rip Oh, Seung-Hwan Won, Hyoung-Bum Koh, Mun-Kwan Kim, David B. Jones, Cecile Massault, Dean R. Jerry, Jehee Lee
Summary: Traits linked to growth performance in farmed fish are important for profitability in aquaculture. A genome-wide association study (GWAS) on olive flounder identified several single nucleotide polymorphisms (SNPs) associated with growth traits. These findings contribute to understanding the molecular basis of growth regulation and promote the use of SNP-based genomic selection in flounder culture.
Article
Environmental Sciences
Ye Ji Kim, Lyu Jin Jun, Da Won Lee, Young Juhn Lee, Ye Jin Ko, Yeong Eun Oh, Soo Ji Woo, Myoung Sug Kim, Seung Min Kim, Joon Bum Jeong
Summary: This study analyzed the antibiotic susceptibility of bacterial pathogens infecting olive flounders in Korea and evaluated the multiple antibiotic resistance of the strains. The results highlight the need for enhanced monitoring of multidrug-resistant bacteria in aquaculture.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Fisheries
HyeongJin Roh, Bo Seong Kim, Gyoungsik Kang, Do-Hyung Kim
Summary: This study aimed to accelerate physical wound healing in flounder using LED technology, showing that 520 and 640 nm LED treatment stimulated cell proliferation, reduced mortality rate, increased skin tissue thickness, and promoted faster wound closure rates. 520 nm LED treatment is an effective and eco-friendly method for aiding recovery from physical injuries in fish, with potential application in aquaculture.
Article
Fisheries
Sang Phil Shin, Chang Nam Jin, Hanchang Sohn, Jehee Lee
Summary: This study aimed to determine the optimal experimental infection method for Enteromyxum leei. The results showed that oral inoculation was more efficient and safer than anal inoculation. Bacterial infection should be considered when diagnosing the mortality of cultured olive flounder infected by E. leei.
Article
Fisheries
Dong-Gyun Kim, Su-Jeong Lee, Jong Min Lee, Eun-Woo Lee, Won Je Jang
Summary: The composition of gut microbiota in flounder changed following infection with pathogenic bacteria. Edwardsiella tarda infection decreased Verrucomicrobia abundance and increased Proteobacteria abundance. Streptococcus iniae infection reduced Verrucomicrobia abundance. Vibrio harveyi infection decreased Firmicutes and Verrucomicrobia abundance and increased Proteobacteria. Infection with all three pathogens increased the relative abundance of Ralstonia and Sphingomonas species and decreased Rubritalea, Saccharimonas, and Bacillus species. Therefore, regulating the gut microbiota composition by reducing Ralstonia and Sphingomonas abundance and increasing Rubritalea, Saccharimonas, and Bacillus abundance might help maintain a healthy gut microbiota balance in flounder. This research could be useful for future studies on improving flounder health through gut microbiota regulation.
Article
Biochemistry & Molecular Biology
Chang Shu, Lijuan Wang, Congcong Zou, Xungang Tan, Yuxia Zou, Lingming Kong, Zhihao Wu, Qiaowan Wu, Ling Wang, Guoyu Wang, Ze Li, Feng You
Summary: This study successfully obtained bioactive recombinant Foxl2 and Dmrt1 proteins and demonstrated that recombinant Dmrt1 can alter the sex phenotype in fish. Furthermore, the injection of recombinant Foxl2 and Dmrt1 resulted in changes in the transcription levels of cyp19a and its transcription factors. These findings reveal the important regulatory roles of Foxl2 and Dmrt1 in fish gonadal differentiation and provide a new approach for sex control in fish aquaculture.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Fisheries
Seong-Mok Jeong, Sanaz Khosravi, Kye-Yoon Yoon, Kang-Woong Kim, Bong-Joo Lee, Sang-Woo Hur, Sang-Min Lee
Summary: Increasing levels of mealworm inclusion in the diet had negative effects on growth rates of juvenile flounders and feed utilization efficiency. However, up to 40% replacement of fish meal with mealworm improved feed utilization efficiency. Different levels of mealworm inclusion also affected nutrient digestibility, plasma cholesterol levels, fatty acid composition in fillets, and immune-related enzyme activities in juvenile flounders.
AQUACULTURE REPORTS
(2021)
Article
Virology
Evelien M. Adriaenssens, Matthew B. Sullivan, Petar Knezevic, Leonardo J. van Zyl, B. L. Sarkar, Bas E. Dutilh, Poliane Alfenas-Zerbini, Malgorzata Lobocka, Yigang Tong, James Rodney Brister, Andrea I. Switt, Jochen Klumpp, Ramy Karam Aziz, Jakub Barylski, Jumpei Uchiyama, Rob A. Edwards, Andrew M. Kropinski, Nicola K. Petty, Martha R. J. Clokie, Alla I. Kushkina, Vera V. Morozova, Siobain Duffy, Annika Gillis, Janis Rumnieks, Ipek Kurtboke, Nina Chanishvili, Lawrence Goodridge, Johannes Wittmann, Rob Lavigne, Ho Bin Jang, David Prangishvili, Francois Enault, Dann Turner, Minna M. Poranen, Hanna M. Oksanen, Mart Krupovic
ARCHIVES OF VIROLOGY
(2020)
Article
Microbiology
Cedric Lood, Katarzyna Danis-Wlodarczyk, Bob G. Blasdel, Ho Bin Jang, Dieter Vandenheuvel, Yves Briers, Jean-Paul Noben, Vera van Noort, Zuzanna Drulis-Kawa, Rob Lavigne
ENVIRONMENTAL MICROBIOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Si Won Kim, Jung Seok Lee, Seong Bin Park, Ae Rin Lee, Jae Wook Jung, Jin Hong Chun, Jassy Mary S. Lazarte, Jaesung Kim, Jong-Su Seo, Jong-Hwan Kim, Jong-Wook Song, Min Woo Ha, Kim D. Thompson, Chang-Ro Lee, Myunghwan Jung, Tae Sung Jung
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Biochemistry & Molecular Biology
Jae Wook Jung, Ae Rin Lee, Jaesung Kim, Young Rim Kim, Jassy Mary S. Lazarte, Jung Suk Lee, Kim D. Thompson, Hyeongsu Kim, Tae Sung Jung
Summary: The study successfully generated monoclonal antibodies against CD8 T lymphocytes in olive flounder and confirmed their specificity. The populations of CD4 and CD8 T lymphocytes significantly increased in fish infected or immunized, with up-regulation of Th1-related genes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Immunology
Jassy Mary S. Lazarte, Young Rim Kim, Jung Seok Lee, Jin Hong Chun, Si Won Kim, Jae Wook Jung, Jaesung Kim, Pattanapon Kayansamruaj, Kim D. Thompson, Hyeongsu Kim, Tae Sung Jung
Summary: This study demonstrates that passive immunization using VLRB-based antibodies can effectively neutralize toxins associated with AHPND, providing a potential alternative to traditional immunoglobulin-based antibodies for managing AHPND outbreaks in shrimp farms.
Article
Immunology
Jin Hong Chun, Jae Wook Jung, Young Rim Kim, Jassy Mary S. Lazarte, Si Won Kim, Jaesung Kim, Kim D. Thompson, Hyoung Jun Kim, Tae Sung Jung
Summary: Poly (I:C)-potentiated vaccination significantly reduces mortality caused by VHSV infection in olive flounder, attributed to the induction of CD4-2(+) T cell immune response by Poly (I:C) and the important role of CD4-2(+) T cells in antiviral response.
Article
Fisheries
Jin-Young Kim, Jeong Su Park, Tae Sung Jung, Hyoung Jun Kim, Se Ryun Kwon
Summary: Chemokines are a superfamily of chemotactic cytokines that regulate leukocyte migration and immune responses. PoCCL34, a fish-specific CC chemokine, induced chemotaxis and inflammatory response in olive flounder, but did not increase expression of antiviral genes. These results suggest that PoCCL34 plays a significant role in the immune response of flounder by mediating inflammation.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Ae Rin Lee, Seong Bin Park, Si Won Kim, Jae Wook Jung, Jin Hong Chun, Jaesung Kim, Young Rim Kim, Jassy Mary S. Lazarte, Ho Bin Jang, Kim D. Thompson, Myunghwan Jung, Min Woo Ha, Tae Sung Jung
Summary: The study demonstrates that membrane vesicles (MVs) from Gram-positive bacteria are capable of transferring beta-lactam antibiotic-resistant substances to antibiotic-sensitive Gram-negative bacteria, resulting in increased resistance to beta-lactam antibiotics.MVs play a role in transferring substances from Gram-positive to Gram-negative bacteria, shown by the release of MVs from RC85-T that were able to protect beta-lactam-susceptible bacteria from beta-lactam antibiotics.
JOURNAL OF APPLIED MICROBIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Apoorva M. Kulkarni, Shraddha Parate, Gihwan Lee, Yongseong Kim, Tae Sung Jung, Keun Woo Lee, Min Woo Ha
Summary: The study utilized computational techniques to validate the potential IL2R alpha binding properties of three polyphenol stilbenes from fenugreek, demonstrating stable interactions with IL2R alpha through molecular docking and molecular dynamics simulations. Rhaponticin showed slightly better binding free energy and all stilbenes followed ADMET rules. Further in vitro IL2R alpha binding studies, especially on rhaponticin, are supported by this computational study.
Article
Polymer Science
Therese Ariane N. Neri, Grace N. Palmos, Shin Young Park, Tae Sung Jung, Byeong-Dae Choi
Summary: Hair plays an important role in framing individual personality and appearance, but there is a lack of groundbreaking measures to solve related problems. Glycosaminoglycans (GAGs) and associated proteoglycans have been found to play important roles in the regulation of the hair follicle cycle. Three fractions (F1, F2, and F3) of GAGs from ascidian tunics were obtained, with F3 showing the highest proliferation activity on human follicle dermal papilla cells. Mixed samples (FFM) of F2 and F3 also exhibited peak activities at different concentrations.
Article
Agriculture, Dairy & Animal Science
Sona Yengkokpam, Narottam Prasad Sahu, Asim Kumar Pal, Dipesh Debnath, Kamal Kant Jain, Rishikesh Subhashrao Dalvi, Petr Slama, Kavindra Kumar Kesari, Shubhadeep Roychoudhury
Summary: Feed deprivation leads to rapid depletion of carbohydrate and lipid stores in rohu fish, accompanied by an increase in gluconeogenic and antioxidant enzyme activities and inhibition of lipogenic enzyme activity. Feed deprivation beyond 30 days causes a reduction in their overall metabolic activities.
Article
Microbiology
Sunghyun Yoon, Yon Kyoung Park, Tae Sung Jung, Seong Bin Park
Summary: In this study, 95 strains of Staphylococcus aureus isolated from stool samples in Busan, South Korea showed diverse antibiotic resistance patterns and distribution of enterotoxin genes. Molecular typing using MALDI-TOF MS and RAPD revealed different clonal lineages among the S. aureus strains.
Article
Microbiology
Seong Bin Park, Yon Kyoung Park, Min Woo Ha, Kim D. Thompson, Tae Sung Jung
Summary: Pathogenic typing, molecular typing, and antimicrobial susceptibility tests were conducted on 75 isolates of E. coli from stool samples of patients suffering from foodborne diseases in Busan, South Korea. The isolates showed high resistance to certain antibiotics but high susceptibility to others, indicating a high level of heterogeneity between the E. coli isolates.
Article
Multidisciplinary Sciences
Hossam Abdelhamed, Seong Won Nho, Si Won Kim, Joseph S. Reddy, Seong Bin Park, Tae Sung Jung, Mark L. Lawrence
Summary: In this study, the potential of MALDI-TOF MS for rapid identification of the foodborne pathogen L. monocytogenes and discrimination of high-risk serotypes was examined. Using MALDI-TOF MS analysis, L. monocytogenes strains were accurately identified as the species and specific serotypes were distinguished based on unique biomarker ions. This method shows promise for rapid identification and serotype discrimination of L. monocytogenes.
Article
Fisheries
Dennis Berbulla Bela-ong, Kim D. Thompson, Hyoung Jun Kim, Seong Bin Park, Tae Sung Jung
Summary: Fish diseases caused by viruses pose a significant threat to aquaculture. Understanding the immune mechanisms involved in antiviral defense is crucial for developing sustainable disease protection strategies. This review focuses on the role of CD4+ T cells in fish immune responses to viral infections and immunomodulation. Studies have shown that CD4+ T cells in fish exhibit similar responses to mammalian Th cells, including proliferation and expression of key cytokines, transcription factors, and effector molecules. Gaps in our understanding of teleost CD4+ T cell responses are discussed, and the development of novel tools and approaches to study these responses is suggested.
FISH & SHELLFISH IMMUNOLOGY
(2023)
