Synthesis, Characterization, and Biological Evaluation of a Dual-Action Ligand Targeting αvβ3Integrin and VEGF Receptors

CyclicisoDGR and RGD Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds are Integrin Antagonists

(2015) Silvia Panzeri et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis and Biological Evaluation of RGD Peptidomimetic-Paclitaxel Conjugates Bearing Lysosomally Cleavable Linkers

(2015) Alberto Dal Corso et al.   CHEMISTRY-A EUROPEAN JOURNAL

18F labeled RGD-A7R peptide for dual integrin and VEGF-targeted tumor imaging in mice bearing U87MG tumors

(2014) Yufei Ma et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Synthesis and biological evaluation of dual action cyclo-RGD/SMAC mimetic conjugates targeting αvβ3/αvβ5 integrins and IAP proteins

(2014) M. Mingozzi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Structural investigation of the VEGF receptor interaction with a helical antagonist peptide

(2013) Donatella Diana et al.   JOURNAL OF PEPTIDE SCIENCE

Helical peptides from VEGF and Vammin hotspots for modulating the VEGF–VEGFR interaction

(2013) María Isabel García-Aranda et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cyclic RGD Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds as New Potent Integrin Ligands

(2012) Mattia Marchini et al.   CHEMISTRY-A EUROPEAN JOURNAL

Tumor vasculature: the Achilles' heel of cancer?

(2012) Tor-Christian Aase Johannessen et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Vascular endothelial growth factor and its receptor system: physiological functions in angiogenesis and pathological roles in various diseases

(2012) M. Shibuya   JOURNAL OF BIOCHEMISTRY

Vascular Endothelial Growth Factor (VEGF) Receptors: Drugs and New Inhibitors

(2012) Francesca Musumeci et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Biological Evaluation (in Vitro and in Vivo) of Cyclic Arginine–Glycine–Aspartate (RGD) Peptidomimetic–Paclitaxel Conjugates Targeting Integrin αVβ3

(2012) Raffaele Colombo et al.   JOURNAL OF MEDICINAL CHEMISTRY

RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis

(2012) Fabienne Danhier et al.   MOLECULAR PHARMACEUTICS

Integrin β3 Crosstalk with VEGFR Accommodating Tyrosine Phosphorylation as a Regulatory Switch

(2012) Xiaoxia Z. West et al.   PLoS One

Characterization of a Designed Vascular Endothelial Growth Factor Receptor Antagonist Helical Peptide with Antiangiogenic Activity in Vivo

(2011) Anna Basile et al.   JOURNAL OF MEDICINAL CHEMISTRY

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

(2011) Peter Carmeliet et al.   NATURE REVIEWS DRUG DISCOVERY

Antagonistic VEGF variants engineered to simultaneously bind to and inhibit VEGFR2 and  v 3 integrin

(2011) N. Papo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Important role of integrins in the cancer biology

(2010) R. Rathinam et al.   CANCER AND METASTASIS REVIEWS

Integrin affinity modulation in angiogenesis

(2010) Ganapati H. Mahabeleshwar et al.   CELL CYCLE

Targeting αvβ3 Integrin: Design and Applications of Mono- and Multifunctional RGD-Based Peptides and Semipeptides

(2010) L. Auzzas et al.   CURRENT MEDICINAL CHEMISTRY

Integrins

(2009) Malgorzata Barczyk et al.   CELL AND TISSUE RESEARCH

Cyclic RGD-Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds as New Potent Integrin Ligands

(2009) Ana Sofia M. da Ressurreição et al.   CHEMISTRY-A EUROPEAN JOURNAL

Small Molecule Integrin Antagonists in Cancer Therapy

(2009) Mayra Paolillo et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

A Peptoid “Antibody Surrogate” That Antagonizes VEGF Receptor 2 Activity

(2008) D. Gomika Udugamasooriya et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY