Synthesis and Biological Evaluation of RGD Peptidomimetic-Paclitaxel Conjugates Bearing Lysosomally Cleavable Linkers

Antibody-Drug Conjugates: An Emerging Concept in Cancer Therapy

(2014) Ravi V. J. Chari et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Histidine–Iridium(III) Coordination-Based Peptide Luminogenic Cyclization and Cyclo-RGD Peptides for Cancer-Cell Targeting

(2014) Xiaochuan Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dual Targeting of Integrin  v 3 and Matrix Metalloproteinase-2 for Optical Imaging of Tumors and Chemotherapeutic Delivery

(2014) J. L. Crisp et al.   MOLECULAR CANCER THERAPEUTICS

Synthesis and biological evaluation of dual action cyclo-RGD/SMAC mimetic conjugates targeting αvβ3/αvβ5 integrins and IAP proteins

(2014) M. Mingozzi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Small Targeted Cytotoxics: Current State and Promises from DNA-Encoded Chemical Libraries

(2013) Nikolaus Krall et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Conjugates of Modified Cryptophycins and RGD-Peptides Enter Target Cells by Endocytosis

(2013) Markus Nahrwold et al.   JOURNAL OF MEDICINAL CHEMISTRY

Tumor Targeting via Integrin Ligands

(2013) Udaya Kiran Marelli et al.   Frontiers in Oncology

Design, Synthesis, and Biological Evaluation of Novel cRGD–Paclitaxel Conjugates for Integrin-Assisted Drug Delivery

(2012) Michael Pilkington-Miksa et al.   BIOCONJUGATE CHEMISTRY

Cyclic RGD Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds as New Potent Integrin Ligands

(2012) Mattia Marchini et al.   CHEMISTRY-A EUROPEAN JOURNAL

Development of Novel Bisphosphonate Prodrugs of Doxorubicin for Targeting Bone Metastases That Are Cleaved pH Dependently or by Cathepsin B: Synthesis, Cleavage Properties, and Binding Properties to Hydroxyapatite As Well As Bone Matrix

(2012) Katrin Hochdörffer et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Biological Evaluation (in Vitro and in Vivo) of Cyclic Arginine–Glycine–Aspartate (RGD) Peptidomimetic–Paclitaxel Conjugates Targeting Integrin αVβ3

(2012) Raffaele Colombo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Direct Fluorescence Monitoring of the Delivery and Cellular Uptake of a Cancer-Targeted RGD Peptide-Appended Naphthalimide Theragnostic Prodrug

(2012) Min Hee Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis

(2012) Fabienne Danhier et al.   MOLECULAR PHARMACEUTICS

Protease-Activated Drug Development

(2012) Ki Young Choi et al.   Theranostics

Drug targeting to tumors: Principles, pitfalls and (pre-) clinical progress

(2011) Twan Lammers et al.   JOURNAL OF CONTROLLED RELEASE

In Vitro and In Vivo Responses of Advanced Prostate Tumors to PSMA ADC, an Auristatin-Conjugated Antibody to Prostate-Specific Membrane Antigen

(2011) X. Wang et al.   MOLECULAR CANCER THERAPEUTICS

Targeting Cell Surface Alpha(v)beta(3) Integrin Increases Therapeutic Efficacies of a Legumain Protease-Activated Auristatin Prodrug

(2011) Yuan Liu et al.   MOLECULAR PHARMACEUTICS

Targeting αvβ3 Integrin: Design and Applications of Mono- and Multifunctional RGD-Based Peptides and Semipeptides

(2010) L. Auzzas et al.   CURRENT MEDICINAL CHEMISTRY

A comparative study of the self-immolation of para-aminobenzylalcohol and hemithioaminal-based linkers in the context of protease-sensitive fluorogenic probes

(2010) Yves Meyer et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Novel tumor-targeted RGD peptide–camptothecin conjugates: Synthesis and biological evaluation

(2009) Alma Dal Pozzo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Evaluation of biodistribution and anti-tumor effect of a dimeric RGD peptide–paclitaxel conjugate in mice with breast cancer

(2008) Qizhen Cao et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

In vitro and in vivo evaluation of a paclitaxel conjugate with the divalent peptide E-[c(RGDfK)2] that targets integrin αvβ3

(2008) Claudia Ryppa et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Conjugated Platinum(IV)−Peptide Complexes for Targeting Angiogenic Tumor Vasculature

(2007) Sumitra Mukhopadhyay et al.   BIOCONJUGATE CHEMISTRY