Article
Microbiology
Nick Vereecke, Sander Van Hoorde, Daniel Sperling, Sebastiaan Theuns, Bert Devriendt, Eric Cox
Summary: This study used nanopore sequencing to investigate ETEC infections in suckling and post-weaning piglets, and identified genetic markers associated with resistance and virulence. The use of these markers for diagnosis will revolutionize genomics-driven diagnostics in veterinary medicine, allowing for simultaneous identification, pathotyping, and genetic AST within a single test.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Multidisciplinary Sciences
Nicola Pellicciotta, Matteo Paoluzzi, Dario Buonomo, Giacomo Frangipane, Luca Angelani, Roberto Di Leonardo
Summary: By modulating bacterial motility with light, researchers have found a way to control the transport direction and speed of microscopic particles by adjusting the active pressure gradients. This discovery provides new insights into the potential use of active pressure for controlled transport of microscopic objects.
NATURE COMMUNICATIONS
(2023)
Article
Multidisciplinary Sciences
Helena Massana-Cid, Claudio Maggi, Giacomo Frangipane, Roberto Di Leonardo
Summary: Optical feedback can be used to confine and gather bacteria, forming dense high-activity regions. This method is general and scalable, making it versatile for microengineering applications and studying non-equilibrium phenomena in active systems.
NATURE COMMUNICATIONS
(2022)
Article
Biology
Yamal Al-ramahi, Akos Nyerges, Yago Margolles, Lidia Cerdan, Gyorgyi Ferenc, Csaba Pal, Luis Angel Fernandez, Victor de Lorenzo
Summary: The study utilized ssDNA recombineering and bacterial surface display to evolve a nanobody recognizing the EHEC antigen TirM towards the EPEC antigen TirM by targeting the CDRs of the VHH gene sequence. This method demonstrated the power of combining bacterial evolutionary properties with oligonucleotide synthesis to focus diversification on specific gene segments of interest, bypassing the need for laborious cloning and mutagenesis procedures.
COMMUNICATIONS BIOLOGY
(2021)
Article
Biochemical Research Methods
Stefano Camborda, Jan-Niklas Weder, Nadine Toepfer
Summary: CobraMod is a Python package for pathway-centric modification and extension of genome-scale metabolic networks. It integrates data from different metabolic pathway databases and user-curated information, and provides high quality metabolic reconstructions.
Article
Infectious Diseases
Pei Yee Woh, May Pui Shan Yeung, William Bernard Goggins
Summary: This study aimed to determine the multiple antibiotic resistance index (MARI) of Salmonella isolated from children hospitalized for gastroenteritis in Hong Kong. The results showed that Salmonella had the highest resistance to ampicillin, ciprofloxacin, and tetracycline, while MDR strains had high resistance towards ampicillin, tetracycline, cotrimoxazole, chloramphenicol, and ciprofloxacin. MARI revealed that 80.2% of Salmonella, including all MDR strains, had indexes greater than 0.2.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2023)
Article
Infectious Diseases
Alec Truswell, Rebecca Abraham, Mark O'Dea, Zheng Zhou Lee, Terence Lee, Tanya Laird, John Blinco, Shai Kaplan, John Turnidge, Darren J. Trott, David Jordan, Sam Abraham
Summary: The robotic platform RASP showed superior throughput and data resolution in high-throughput AMR surveillance compared to an experienced human technician, achieving consistent MICs and demonstrating potential in identifying diversity in fecal samples.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2021)
Article
Multidisciplinary Sciences
Enrico Orsi, Nico J. Claassens, Pablo Nikel, Steffen N. Lindner
Summary: Synthetic biology has revolutionized the ability to redesign microbial metabolic networks by combining metabolic pathway-modularization with growth-coupled selection schemes. This powerful tool enables deep rewiring of cell factories' biochemistry for rational bioproduction.
NATURE COMMUNICATIONS
(2021)
Article
Infectious Diseases
Meng-Ke Zhang, Meng-Yao Zhang, Shuo-Bo Liu, Ying-Ying Yang, Ya-Jun Zhai, Dan-Dan He, Hua Wu, Yu-Shan Pan, Jian-Hua Liu, Li Yuan, Gong-Zheng Hu
Summary: This study revealed that the double deletion of cpxR and tolC significantly increases the susceptibility of S. Typhimurium to colistin. The molecular mechanisms underlying this phenomenon were elucidated through transcriptomic analysis.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2021)
Article
Multidisciplinary Sciences
Olivia Dwijayanti Wiguna, Diana Elizabeth Waturangi, Yogiara
Summary: This study found that DW-EC bacteriophage isolated from Indonesian traditional food has inhibitory and destructive effects on the biofilms of pathogenic E. coli, and its activity is significantly higher than that against B. cereus. This indicates that DW-EC bacteriophage has the potential to be used as an anti-biofilm candidate for polystyrene and stainless steel equipment in the food industry.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Bhishem Thakur, Kanika Arora, Archit Gupta, Purnananda Guptasarma
Summary: Researchers investigated whether the nucleoid-associated histone-like protein (HU) could act as a glue in biofilms, finding evidence through various experiments to support this hypothesis.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Wen Liu, Linbo Wei, Dongmei Wang, Chengye Zhu, Yuting Huang, Zhengjun Gong, Changyu Tang, Meikun Fan
Summary: This study proposes a method to enhance the differentiation of bacterial SERS spectra by applying external environmental stress. The results show that appropriate stress can increase the differences in bacterial SERS spectra.
ANALYTICAL CHEMISTRY
(2022)
Review
Microbiology
Samiran Banerjee, Marcel G. A. van der Heijden
Summary: The concept of one health emphasizes the interconnectedness of human health with the health of animals, plants, and the environment. This review focuses on the role of soils as a cornerstone of one health, serving as a source and reservoir of pathogens, beneficial microorganisms, and overall microbial diversity. The study highlights the interconnectedness between soil, plant, and human microbiomes and discusses the contributions of soil microbial diversity to one health, considering dysbiosis and global change. Future challenges and recommendations for one health research are presented.
NATURE REVIEWS MICROBIOLOGY
(2023)
Article
Chemistry, Analytical
Jin-Yuan Chen, Qing-Xia Wei, Liang-Yong Yang, Jia-Yi Li, Tai-Cheng Lu, Zhou-Jie Liu, Guang-Xian Zhong, Xiu-Hua Weng, Xiong-Wei Xu
Summary: This study proposed a multimodal aptasensor for the detection of ochratoxin A (OTA). By using 3'-FAM labeled aptamers and Exo I tool, the aptasensor offers a promising substitute for antibody-dependent biosensors due to its preparatory ease, close affinity, and low cost. However, current aptasensors are mostly limited to single-mode readout and face interference from unbound aptamers and non-target-induced transition events.
ANALYTICAL CHEMISTRY
(2022)
Review
Microbiology
Samiran Banerjee, Marcel G. A. van der Heijden
Summary: The concept of one health emphasizes the interconnectedness of human health with the health of animals, plants, and environments. This review highlights the importance of soils as a source and reservoir of pathogens, beneficial microorganisms, and microbial diversity in various organisms and ecosystems. The study identifies shared microorganisms between different components of one health and reveals the interconnectedness of soil, plant, and human microbiomes. It also demonstrates that microbial diversity is generally associated with one health, while considering dysbiosis and global change. The review provides future challenges and recommendations for one health research.
NATURE REVIEWS MICROBIOLOGY
(2023)
Article
Gastroenterology & Hepatology
Xia Xiong, Huansheng Yang, Bie Tan, Chengbo Yang, Miaomiao Wu, Gang Liu, Sung Woo Kim, Tiejun Li, Lili Li, Junjun Wang, Guoyao Wu, Yulong Yin
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
(2015)
Article
Biochemistry & Molecular Biology
Jielin Duan, Jie Yin, Wenkai Ren, Ting Liu, Zhijie Cui, Xingguo Huang, Li Wu, Sung Woo Kim, Gang Liu, Xi Wu, Guoyao Wu, Tiejun Li, Yulong Yin
Review
Immunology
Wenkai Ren, Jie Yin, Jielin Duan, Gang Liu, Bie Tan, Guan Yang, Guoyao Wu, Fuller W. Bazer, Yuanyi Peng, Yulong Yin
EUROPEAN JOURNAL OF IMMUNOLOGY
(2016)
Review
Biochemistry & Molecular Biology
Miaomiao Bai, Hongnan Liu, Kang Xu, Abimbola Oladele Oso, Xin Wu, Gang Liu, Myrlene Carine B. Tossou, Naif Abdullah Al-Dhabi, Veeramuthu Duraipandiyan, Qianyun Xi, Yinlong Yin
Article
Integrative & Complementary Medicine
Tarique Hussain, Bi'e Tan, Gang Liu, Oso Abimbola Oladele, Najma Rahu, M. C. Tossou, Yulong Yin
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2016)
Article
Cell Biology
Wenkai Ren, Shuai Chen, Liwen Zhang, Gang Liu, Tarique Hussain, Xiao Hao, Jie Yin, Jielin Duan, Bie Tan, Guoyao Wu, Fuller W. Bazer, Yulong Yin
MEDIATORS OF INFLAMMATION
(2016)
Article
Cell Biology
Gang Liu, Shuai Chen, Guiping Guan, Jun Tan, Naif A. Al-Dhabi, Hongbing Wang, Veeramuthu Duraipandiyan, Jun Fang
MEDIATORS OF INFLAMMATION
(2016)
Article
Food Science & Technology
Dingfu Xiao, Wenkai Ren, Peng Bin, Shuai Chen, Jie Yin, Wei Gao, Gang Liu, Zi Nan, Xionggui Hu, Jianhua He
JOURNAL OF FUNCTIONAL FOODS
(2016)
Article
Multidisciplinary Sciences
Wenkai Ren, Jie Yin, Shuai Chen, Jielin Duan, Gang Liu, Tiejun Li, Nengzhang Li, Yuanyi Peng, Bie Tan, Yulong Yin
SCIENTIFIC REPORTS
(2016)
Review
Biotechnology & Applied Microbiology
Hengjia Ni, Yordan Martinez, Guiping Guan, Roman Rodriguez, Dairon Mas, Hanhui Peng, Manuel Valdivie Navarro, Gang Liu
BIOMED RESEARCH INTERNATIONAL
(2016)
Article
Biotechnology & Applied Microbiology
Myrlene Carine B. Tossou, Hongnan Liu, Miaomiao Bai, Shuai Chen, Yinghua Cai, Veeramuthu Duraipandiyan, Hongbin Liu, Tolulope O. Adebowale, Naif Abdullah Al-Dhabi, Lina Long, Hussain Tarique, Abimbola O. Oso, Gang Liu, Yulong Yin
BIOMED RESEARCH INTERNATIONAL
(2016)
Article
Biotechnology & Applied Microbiology
Gang Liu, Guiping Guan, Jun Fang, Yordan Martinez, Shuai Chen, Peng Bin, Veeramuthu Duraipandiyan, Ting Gong, Myrlene Carine B. Tossou, Naif Abdullah Al-Dhabi, Yulong Yin
BIOMED RESEARCH INTERNATIONAL
(2016)
Article
Agriculture, Dairy & Animal Science
Jing Wang, Liming Zeng, Bie Tan, Guangran Li, Bo Huang, Xia Xiong, Fengna Li, Xiangfeng Kong, Gang Liu, Yulong Yin
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2016)
Review
Immunology
Wenkai Ren, Kai Wang, Jie Yin, Shuai Chen, Gang Liu, Bie Tan, Guoyao Wu, Fuller W. Bazer, Yuanyi Peng, Yulong Yin
FRONTIERS IN IMMUNOLOGY
(2016)
Article
Cell Biology
Gang Liu, Lei Yu, Yordan Martinez, Wenkai Ren, Hengjia Ni, Naif Abdullah Al-Dhabi, Veeramuthu Duraipandiyan, Yulong Yin
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
(2017)