Probing the Surface of Human Carbonic Anhydrase for Clues towards the Design of Isoform Specific Inhibitors
出版年份 2015 全文链接
标题
Probing the Surface of Human Carbonic Anhydrase for Clues towards the Design of Isoform Specific Inhibitors
作者
关键词
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出版物
Biomed Research International
Volume 2015, Issue -, Pages 1-15
出版商
Hindawi Limited
发表日期
2015-02-25
DOI
10.1155/2015/453543
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- (2013) Melissa A. Pinard et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Optimization of heterocyclic substituted benzenesulfonamides as novel carbonic anhydrase IX inhibitors and their structure activity relationship
- (2013) Rui Gao et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
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- (2013) Claudiu T Supuran EXPERT OPINION ON THERAPEUTIC PATENTS
- Wirkmechanismen, klinisches Profil und Stellenwert von Carboanhydrasehemmern in der antiglaukomatösen Therapie
- (2013) M. Eichhorn KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE
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- (2012) Ewa S. Pilka et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2012) Rose Mikulski et al. BIOCHEMISTRY
- Novel coumarins and 2-thioxo-coumarins as inhibitors of the tumor-associated carbonic anhydrases IX and XII
- (2012) Fabrizio Carta et al. BIOORGANIC & MEDICINAL CHEMISTRY
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- (2012) Mayank Aggarwal et al. BIOORGANIC & MEDICINAL CHEMISTRY
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- (2012) Rohan A. Davis et al. BIOORGANIC & MEDICINAL CHEMISTRY
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- (2012) Emanuela Truppo et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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- (2012) Fabrizio Carta et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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- (2012) Vincenzo Alterio et al. CHEMICAL REVIEWS
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- (2012) Barend Andre Stander et al. PLoS One
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- (2011) PIRITTA HYNNINEN et al. APMIS
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- (2011) Oscar M. Rodríguez et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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- (2011) Fabrizio Carta et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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- (2011) Y. Lou et al. CANCER RESEARCH
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- (2011) Fabrizio Carta et al. CHEMICAL COMMUNICATIONS
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- (2011) Marie Lopez et al. JOURNAL OF MEDICINAL CHEMISTRY
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- (2011) Lorena A. Vargas et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds
- (2011) Katherine H. Sippel et al. Letters in Drug Design & Discovery
- Tumor-associated carbonic anhydrase XII is linked to the growth of primary oral squamous cell carcinoma and its poor prognosis
- (2011) Ming-Hsien Chien et al. ORAL ONCOLOGY
- A New Peptide Ligand for Targeting Human Carbonic Anhydrase IX, Identified through the Phage Display Technology
- (2011) Vasileios Askoxylakis et al. PLoS One
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- (2010) Fatemeh Bootorabi et al. BIOCHIMIE
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- (2010) Alfonso Maresca et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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- (2010) Kristiina Nordfors et al. BMC CANCER
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- (2010) Emad Muhammad et al. HUMAN GENETICS
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- (2010) Marius I. Ilie et al. INTERNATIONAL JOURNAL OF CANCER
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- (2010) Fabrizio Carta et al. JOURNAL OF MEDICINAL CHEMISTRY
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- (2010) P Swietach et al. ONCOGENE
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- (2009) Ying Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2009) Balendu Sankara Avvaru et al. BIOCHEMISTRY
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- (2009) Marina Asiedu et al. PAIN
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- Carbonic Anhydrase as a Model for Biophysical and Physical-Organic Studies of Proteins and Protein−Ligand Binding
- (2008) Vijay M. Krishnamurthy et al. CHEMICAL REVIEWS
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- (2008) Claudiu Supuran CURRENT PHARMACEUTICAL DESIGN
- Entrapment of Carbon Dioxide in the Active Site of Carbonic Anhydrase II
- (2008) John F. Domsic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
- (2008) Claudiu T. Supuran NATURE REVIEWS DRUG DISCOVERY
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