Docosahexaenoic Acid Modulates a HER2-Associated Lipogenic Phenotype, Induces Apoptosis, and Increases Trastuzumab Action in HER2-Overexpressing Breast Carcinoma Cells

High Pathologic Complete Response in Her2-Positive, Early-Stage Breast Cancer to a Novel Nonanthracycline Neoadjuvant Chemotherapy

(2015) Amelia B. Zelnak et al.   Clinical Breast Cancer

Arachidonic acid has a dominant effect to regulate lipogenic genes in 3T3-L1 adipocytes compared to omega-3 fatty acids

(2015) Hitesh Vaidya et al.   Food & Nutrition Research

An Evolving Role for DEPTOR in Tumor Development and Progression

(2015) Zhiwei Wang et al.   NEOPLASIA

PI3K/Akt is involved in brown adipogenesis mediated by growth differentiation factor-5 in association with activation of the Smad pathway

(2014) Eiichi Hinoi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

HER2-positive advanced breast cancer: optimizing patient outcomes and opportunities for drug development

(2014) J C Singh et al.   BRITISH JOURNAL OF CANCER

Targeting PI3K/mTOR Overcomes Resistance to HER2-Targeted Therapy Independent of Feedback Activation of AKT

(2014) N. A. O'Brien et al.   CLINICAL CANCER RESEARCH

The mTOR Inhibitor Rapamycin Synergizes with a Fatty Acid Synthase Inhibitor to Induce Cytotoxicity in ER/HER2-Positive Breast Cancer Cells

(2014) Chen Yan et al.   PLoS One

Dietary PUFA and cancer

(2014) S. Abel et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Adult adipose-derived stem cells and breast cancer: a controversial relationship

(2014) Alessandra Bielli et al.   SpringerPlus

Omega-3 phospholipids from fish suppress hepatic steatosis by integrated inhibition of biosynthetic pathways in dietary obese mice

(2013) Martin Rossmeisl et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

n-3 polyunsaturated fatty acids and HER2-positive breast cancer: Interest of the fat-1 transgenic mouse model over conventional dietary supplementation

(2013) Zuquan Zou et al.   BIOCHIMIE

Repression of mammary adipogenesis by genistein limits mammosphere formation of human MCF-7 cells

(2013) Maria Theresa E Montales et al.   JOURNAL OF ENDOCRINOLOGY

Modulation of adipose tissue inflammation by bioactive food compounds

(2013) Nalin Siriwardhana et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Fatty acid synthase expression is strongly related to menopause in early-stage breast cancer patients

(2013) Rut Porta et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Differential effects of eicosapentaenoic acid and docosahexaenoic acid in promoting the differentiation of 3T3-L1 preadipocytes

(2013) Ganesan Murali et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Chemical–Physical Changes in Cell Membrane Microdomains of Breast Cancer Cells After Omega-3 PUFA Incorporation

(2012) Paola A. Corsetto et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

DEPTOR Cell-Autonomously Promotes Adipogenesis, and Its Expression Is Associated with Obesity

(2012) Mathieu Laplante et al.   Cell Metabolism

Lipid raft disruption by docosahexaenoic acid induces apoptosis in transformed human mammary luminal epithelial cells harboring HER-2 overexpression

(2012) Graziela Rosa Ravacci et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Trastuzumab Produces Therapeutic Actions by Upregulating miR-26a and miR-30b in Breast Cancer Cells

(2012) Takehiro Ichikawa et al.   PLoS One

The Lipid Phenotype of Breast Cancer Cells Characterized by Raman Microspectroscopy: Towards a Stratification of Malignancy

(2012) Claudia Nieva et al.   PLoS One

Trastuzumab Has Preferential Activity against Breast Cancers Driven by HER2 Homodimers

(2011) R. Ghosh et al.   CANCER RESEARCH

p95HER2 and Breast Cancer

(2011) J. Arribas et al.   CANCER RESEARCH

Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression

(2011) M. Hilvo et al.   CANCER RESEARCH

FOXO1A Is a Target for HER2-Overexpressing Breast Tumors

(2010) Y. Wu et al.   CANCER RESEARCH

HER-2 Signaling, Acquisition of Growth Factor Independence, and Regulation of Biological Networks Associated with Cell Transformation

(2010) A. Bollig-Fischer et al.   CANCER RESEARCH

An RNA Interference Screen Identifies Metabolic Regulators NR1D1 and PBP as Novel Survival Factors for Breast Cancer Cells with the ERBB2 Signature

(2010) A. Kourtidis et al.   CANCER RESEARCH

Docosahexaenoic acid alters epidermal growth factor receptor-related signaling by disrupting its lipid raft association

(2010) Kristina R. Rogers et al.   CARCINOGENESIS

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Fine-tuning the lipogenic/lipolytic balance to optimize the metabolic requirements of cancer cell growth: Molecular mechanisms and therapeutic perspectives

(2009) Javier A. Menendez   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Poor survival outcomes in HER2-positive breast cancer patients with low-grade, node-negative tumours

(2009) S M Tovey et al.   BRITISH JOURNAL OF CANCER

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

(2009) Timothy R. Peterson et al.   CELL

As a Matter of Fat

(2009) Rita T. Brookheart et al.   Cell Metabolism

An Emerging Role of mTOR in Lipid Biosynthesis

(2009) Mathieu Laplante et al.   CURRENT BIOLOGY

A maternal high n-6 fat diet with fish oil supplementation during pregnancy and lactation in rats decreases breast cancer risk in the female offspring

(2009) Hui-Min Su et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Thematic Review Series: Glycerolipids.DGAT enzymes and triacylglycerol biosynthesis

(2008) Chi-Liang Eric Yen et al.   JOURNAL OF LIPID RESEARCH

Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines

(2008) Edurne Arriola et al.   LABORATORY INVESTIGATION

The lipidome as a composite biomarker of the modifiable part of the risk of breast cancer

(2008) Philippe Bougnoux et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS