Design of biomaterials for intracellular delivery of carbon monoxide

The chemistry, biology and design of photochemical CO releasing molecules and the efforts to detect CO for biological applications

(2016) Jon Marhenke et al.   COORDINATION CHEMISTRY REVIEWS

Design, Synthesis, and Functional Evaluation of CO-Releasing Molecules Triggered by Penicillin G Amidase as a Model Protease

(2015) Nikolay S. Sitnikov et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An artificial CO-releasing metalloprotein built by histidine-selective metallation

(2015) Inês S. Albuquerque et al.   CHEMICAL COMMUNICATIONS

A photoCORM nanocarrier for CO release using NIR light

(2015) Agustin E. Pierri et al.   CHEMICAL COMMUNICATIONS

Gaseous O2, NO, and CO in Signal Transduction: Structure and Function Relationships of Heme-Based Gas Sensors and Heme-Redox Sensors

(2015) Toru Shimizu et al.   CHEMICAL REVIEWS

Design of a CO-releasing Extracellular Scaffold Using in Vivo Protein Crystals

(2015) Hiroyasu Tabe et al.   CHEMISTRY LETTERS

Carbon monoxide release properties and molecular structures of phenylthiolatomanganese(i) carbonyl complexes of the type [(OC)4Mn(μ-S-aryl)]2

(2015) Ralf Mede et al.   DALTON TRANSACTIONS

Design Strategies To Improve the Sensitivity of Photoactive Metal Carbonyl Complexes (photoCORMs) to Visible Light and Their Potential as CO-Donors to Biological Targets

(2014) Indranil Chakraborty et al.   ACCOUNTS OF CHEMICAL RESEARCH

Spontaneous CO Release from RuII(CO)2-Protein Complexes in Aqueous Solution, Cells, and Mice

(2014) Miguel Chaves-Ferreira et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carbon-Monoxide-Releasing Molecules for the Delivery of Therapeutic CO In Vivo

(2014) Sandra García-Gallego et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carbon monoxide – physiology, detection and controlled release

(2014) Stefan H. Heinemann et al.   CHEMICAL COMMUNICATIONS

Design and Synthesis of New Hybrid Molecules That Activate the Transcription Factor Nrf2 and Simultaneously Release Carbon Monoxide

(2014) Jayne Louise Wilson et al.   CHEMISTRY-A EUROPEAN JOURNAL

Caged protein nanoparticles for drug delivery

(2014) Nicholas M Molino et al.   CURRENT OPINION IN BIOTECHNOLOGY

Recent achievments in the design and engineering of artificial metalloenzymes

(2014) Marc Dürrenberger et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

New modular manganese(i) tricarbonyl complexes as PhotoCORMs: in vitro detection of photoinduced carbon monoxide release using COP-1 as a fluorogenic switch-on probe

(2014) Sandesh Pai et al.   DALTON TRANSACTIONS

Sonogashira, CuAAC, and Oxime Ligations for the Synthesis of MnITricarbonyl PhotoCORM Peptide Conjugates

(2014) Sandesh Pai et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Preparation of a Cross-Linked Porous Protein Crystal Containing Ru Carbonyl Complexes as a CO-Releasing Extracellular Scaffold

(2014) Hiroyasu Tabe et al.   INORGANIC CHEMISTRY

Styrene-maleic acid copolymer-encapsulated CORM2, a water-soluble carbon monoxide (CO) donor with a constant CO-releasing property, exhibits therapeutic potential for inflammatory bowel disease

(2014) Hongzhuan Yin et al.   JOURNAL OF CONTROLLED RELEASE

Intracellular CO Release from Composite of Ferritin and Ruthenium Carbonyl Complexes

(2014) Kenta Fujita et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Characterization of a “Turn-On” photoCORM for Trackable CO Delivery to Biological Targets

(2014) Samantha J. Carrington et al.   ACS Medicinal Chemistry Letters

Light-triggered carbon monoxide delivery with Al-MCM-41-based nanoparticles bearing a designed manganese carbonyl complex

(2014) Margarita A. Gonzales et al.   Journal of Materials Chemistry B

Light-triggered CO release from nanoporous non-wovens

(2014) Carmen Bohlender et al.   Journal of Materials Chemistry B

Different design of enzyme-triggered CO-releasing molecules (ET-CORMs) reveals quantitative differences in biological activities in terms of toxicity and inflammation

(2014) E. Stamellou et al.   Redox Biology

Metal carbonyls supported on iron oxide nanoparticles to trigger the CO-gasotransmitter release by magnetic heating

(2013) Peter C. Kunz et al.   CHEMICAL COMMUNICATIONS

Iron Metal-Organic Frameworks MIL-88B and NH2-MIL-88B for the Loading and Delivery of the Gasotransmitter Carbon Monoxide

(2013) Mingyan Ma et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enzyme-triggered CO-releasing molecules (ET-CORMs): Evaluation of biological activity in relation to their structure

(2013) S. Romanski et al.   FREE RADICAL BIOLOGY AND MEDICINE

Next Generation PhotoCORMs: Polynuclear Tricarbonylmanganese(I)-Functionalized Polypyridyl Metallodendrimers

(2013) Preshendren Govender et al.   INORGANIC CHEMISTRY

Synthesis, Spectroscopic Properties, and Photoinduced CO-Release Studies of Functionalized Ruthenium(II) Polypyridyl Complexes: Versatile Building Blocks for Development of CORM–Peptide Nucleic Acid Bioconjugates

(2013) Caroline Bischof et al.   INORGANIC CHEMISTRY

Photoactive metal carbonyl complexes as potential agents for targeted CO delivery

(2013) Margarita A. Gonzales et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Live-Fibroblast IR Imaging of a Cytoprotective PhotoCORM Activated with Visible Light

(2013) Fabio Zobi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Visible-light activatable organic CO-releasing molecules (PhotoCORMs) that simultaneously generate fluorophores

(2013) Ping Peng et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Fluorescein Analogue Xanthene-9-Carboxylic Acid: A Transition-Metal-Free CO Releasing Molecule Activated by Green Light

(2013) Lovely Angel Panamparambil Antony et al.   ORGANIC LETTERS

Synthesis and Performance of Acyloxy-diene-Fe(CO)3 Complexes with Variable Chain Lengths as Enzyme-Triggered Carbon Monoxide-Releasing Molecules

(2013) Svetlana Botov et al.   ORGANOMETALLICS

Sulfite species enhance carbon monoxide release from CO-releasing molecules: Implications for the deoxymyoglobin assay of activity

(2012) Samantha McLean et al.   ANALYTICAL BIOCHEMISTRY

CuAAC click functionalization of azide-modified nanodiamond with a photoactivatable CO-releasing molecule (PhotoCORM) based on [Mn(CO)3(tpm)]+

(2012) G. Dördelmann et al.   CHEMICAL COMMUNICATIONS

Developing drug molecules for therapy with carbon monoxide

(2012) Carlos C. Romão et al.   CHEMICAL SOCIETY REVIEWS

Acyloxybutadiene tricarbonyl iron complexes as enzyme-triggered CO-releasing molecules (ET-CORMs): a structure–activity relationship study

(2012) Steffen Romanski et al.   DALTON TRANSACTIONS

A therapeutically viable photo-activated manganese-based CO-releasing molecule (photo-CO-RM)

(2012) Jonathan S. Ward et al.   DALTON TRANSACTIONS

Syntheses, Structures, and Properties of New Manganese Carbonyls as Photoactive CO-Releasing Molecules: Design Strategies That Lead to CO Photolability in the Visible Region

(2012) Margarita A. Gonzalez et al.   INORGANIC CHEMISTRY

Bioorthogonal oxime ligation of a Mo(CO)4(N–N) CO-releasing molecule (CORM) to a TGF β-binding peptide

(2012) Hendrik Pfeiffer et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

A Luminescent and Biocompatible PhotoCORM

(2012) Agustin E. Pierri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron Dienylphosphate Tricarbonyl Complexes as Water-Soluble Enzyme-Triggered CO-Releasing Molecules (ET-CORMs)

(2012) Steffen Romanski et al.   ORGANOMETALLICS

CO Release from Norbornadiene Iron(0) Tricarbonyl Complexes: Importance of Ligand Dissociation

(2012) Anthony J. Atkin et al.   ORGANOMETALLICS

Generation of Carbon Monoxide Releasing Molecules (CO-RMs) as Drug Candidates for the Treatment of Acute Liver Injury: Targeting of CO-RMs to the Liver

(2012) Ana R. Marques et al.   ORGANOMETALLICS

A peptide-based material for therapeutic carbon monoxide delivery

(2012) John B. Matson et al.   Soft Matter

The social network of carbon monoxide in medicine

(2012) Barbara Wegiel et al.   TRENDS IN MOLECULAR MEDICINE

Acyloxybutadiene Iron Tricarbonyl Complexes as Enzyme-Triggered CO-Releasing Molecules (ET-CORMs)

(2011) Steffen Romanski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Novel Carbon Monoxide-Releasing Molecule Fully Protects Mice from Severe Malaria

(2011) Ana C. Pena et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Photochemically activated carbon monoxide release for biological targets. Toward developing air-stable photoCORMs labilized by visible light

(2011) R. Dale Rimmer et al.   COORDINATION CHEMISTRY REVIEWS

17 e−rhenium dicarbonyl CO-releasing molecules on a cobalamin scaffold for biological application

(2011) Fabio Zobi et al.   DALTON TRANSACTIONS

Polymer Conjugates of Photoinducible CO-Releasing Molecules

(2011) Nadine E. Brückmann et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Synthesis, Characterization, and Reactivity of the Stable Iron Carbonyl Complex [Fe(CO)(N4Py)](ClO4)2: Photoactivated Carbon Monoxide Release, Growth Inhibitory Activity, and Peptide Ligation

(2011) Casey S. Jackson et al.   INORGANIC CHEMISTRY

Manganese Carbonyls Bearing Tripodal Polypyridine Ligands as Photoactive Carbon Monoxide-Releasing Molecules

(2011) Margarita A. Gonzalez et al.   INORGANIC CHEMISTRY

Silicium Dioxide Nanoparticles As Carriers for Photoactivatable CO-Releasing Molecules (PhotoCORMs)

(2011) Gregor Dördelmann et al.   INORGANIC CHEMISTRY

PhotoCORMs: Light-triggered release of carbon monoxide from the coordination sphere of transition metal complexes for biological applications

(2011) Ulrich Schatzschneider   INORGANICA CHIMICA ACTA

Synthesis and Reactivity of Molybdenum Complexes Containing Functionalized Alkynyl Ligands: A Photochemically Activated CO-Releasing Molecule (PhotoCO-RM)

(2011) Wei-Qiang Zhang et al.   ORGANOMETALLICS

Imaging and drug delivery using theranostic nanoparticles

(2010) Siti M. Janib et al.   ADVANCED DRUG DELIVERY REVIEWS

Heme oxygenase-1 comes back to endoplasmic reticulum

(2010) Hong Pyo Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dicarbonyl-bis(cysteamine)iron(II): A light induced carbon monoxide releasing molecule based on iron (CORM-S1)

(2010) Robert Kretschmer et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Carbon Monoxide-Releasing Micelles for Immunotherapy

(2010) Urara Hasegawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The therapeutic potential of carbon monoxide

(2010) Roberto Motterlini et al.   NATURE REVIEWS DRUG DISCOVERY

Syntheses, structural characterization and CO releasing properties of boranocarbonate [H3BCO2H]− derivatives

(2010) Tamil Selvi Pitchumony et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Interactions of Multiple Gas-Transducing Systems: Hallmarks and Uncertainties of CO, NO, and H2S Gas Biology

(2009) Mayumi Kajimura et al.   ANTIOXIDANTS & REDOX SIGNALING

Sonogashira and “Click” reactions for the N-terminal and side-chain functionalization of peptides with [Mn(CO)3(tpm)]+-based CO releasing molecules (tpm = tris(pyrazolyl)methane)

(2009) Hendrik Pfeiffer et al.   DALTON TRANSACTIONS

Tricarbonylmanganese(I) and –rhenium(I) Complexes of Imidazol-Based Phosphane Ligands: Influence of the Substitution Pattern on the CO Release Properties

(2009) Peter C. Kunz et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

A Photochemical Precursor for Carbon Monoxide Release in Aerated Aqueous Media

(2009) R. Dale Rimmer et al.   INORGANIC CHEMISTRY

Design of functional metalloproteins

(2009) Yi Lu et al.   NATURE

Protein-Based Nanomedicine Platforms for Drug Delivery

(2009) Aihui MaHam et al.   Small

Photoinduced CO release, cellular uptake and cytotoxicity of a tris(pyrazolyl)methane (tpm) manganese tricarbonyl complex

(2008) Johanna Niesel et al.   CHEMICAL COMMUNICATIONS

Derivatives of Sodium Boranocarbonate as Novel CO-Releasing Molecules (CO-RMs)

(2008) Tamil S. Pitchumony et al.   CHIMIA