Downregulation of Skp2 inhibits the growth and metastasis of gastric cancer cells in vitro and in vivo

Characterization of Gene Amplification-Driven SKP2 Overexpression in Myxofibrosarcoma: Potential Implications in Tumor Progression and Therapeutics

(2012) C.-F. Li et al.   CLINICAL CANCER RESEARCH

Skp2 is a Promising Therapeutic Target in Breast Cancer

(2012) Zhiwei Wang et al.   Frontiers in Oncology

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Downregulating hypoxia-inducible factor-2α improves the efficacy of doxorubicin in the treatment of hepatocellular carcinoma

(2011) Changjun He et al.   CANCER SCIENCE

Involvement of the SKP2–p27KIP1 pathway in suppression of cancer cell proliferation by RECK

(2011) Y Yoshida et al.   ONCOGENE

Ubiquitylation and proteasomal degradation of the p21Cip1, p27Kip1and p57Kip2CDK inhibitors

(2010) Zhimin Lu et al.   CELL CYCLE

Overexpression of von Hippel–Lindau protein synergizes with doxorubicin to suppress hepatocellular carcinoma in mice

(2010) Jizhou Wang et al.   JOURNAL OF HEPATOLOGY

Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis

(2010) Chia-Hsin Chan et al.   NATURE CELL BIOLOGY

Correlation between Skp2 expression and nodal metastasis in Stage I and II oral squamous cell carcinomas

(2010) P Tosco et al.   ORAL DISEASES

Skp2 overexpression increases the expression of MMP-2 and MMP-9 and invasion of lung cancer cells

(2009) Wen-Chun Hung et al.   CANCER LETTERS

Downregulation of nuclear factor-κB p65 subunit by small interfering RNA synergizes with gemcitabine to inhibit the growth of pancreatic cancer

(2009) Rui Kong et al.   CANCER LETTERS

SKP2 and CKS1 Promote Degradation of Cell Cycle Regulators and Are Associated With Hepatocellular Carcinoma Prognosis

(2009) Diego F. Calvisi et al.   GASTROENTEROLOGY

Suppression of Anoikis bySKP2Amplification and Overexpression Promotes Metastasis of Esophageal Squamous Cell Carcinoma

(2009) Xiao-Chun Wang et al.   MOLECULAR CANCER RESEARCH

Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction

(2009) Daming Gao et al.   NATURE CELL BIOLOGY

Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB

(2009) Hui-Kuan Lin et al.   NATURE CELL BIOLOGY

Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/− mice

(2009) Hongbo Wang et al.   NATURE GENETICS

Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model

(2009) E. Susaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Skp2-p27 Axis by the Cdh1/Anaphase-Promoting Complex Pathway in Colorectal Tumorigenesis

(2008) Takeo Fujita et al.   AMERICAN JOURNAL OF PATHOLOGY

Oncogenic properties and prognostic implications of the ubiquitin ligase Skp2 in cancer

(2008) Dan D. Hershko   CANCER

Locoregional treatment of peritoneal carcinomatosis from gastric cancer

(2008) F. Bozzetti et al.   JOURNAL OF SURGICAL ONCOLOGY

Progress in matrix metalloproteinase research

(2008) G MURPHY et al.   MOLECULAR ASPECTS OF MEDICINE

Skp2 Suppresses p53-Dependent Apoptosis by Inhibiting p300

(2008) Mayumi Kitagawa et al.   MOLECULAR CELL