GABA Protects Human Islet Cells Against the Deleterious Effects of Immunosuppressive Drugs and Exerts Immunoinhibitory Effects Alone

γ-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes

(2012) J. Taneera et al.   DIABETOLOGIA

Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2)

(2012) A. D. Barlow et al.   DIABETOLOGIA

Ca2+ regulates T-cell receptor activation by modulating the charge property of lipids

(2012) Xiaoshan Shi et al.   NATURE

Analysis of Beta-Cell Gene Expression Reveals Inflammatory Signaling and Evidence of Dedifferentiation following Human Islet Isolation and Culture

(2012) Sarita Negi et al.   PLoS One

Different Subtypes of GABA-A Receptors Are Expressed in Human, Mouse and Rat T Lymphocytes

(2012) Suresh K. Mendu et al.   PLoS One

Caspase Inhibitor IDN6556 Facilitates Marginal Mass Islet Engraftment in a Porcine Islet Autotransplant Model

(2012) Michael D. McCall et al.   TRANSPLANTATION

Oral GABA treatment downregulates inflammatory responses in a mouse model of rheumatoid arthritis

(2011) Jide Tian et al.   AUTOIMMUNITY

Calcium signalling in T-lymphocytes

(2011) V. Robert et al.   BIOCHIMIE

NF-κB in immunobiology

(2011) Matthew S Hayden et al.   CELL RESEARCH

State of the Art of Clinical Islet Transplantation and Novel Protocols of Immunosuppression

(2011) A. M. James Shapiro   Current Diabetes Reports

The Evolving Role of mTOR Inhibition in Transplantation Tolerance

(2011) G. McMahon et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Oral Treatment with γ-Aminobutyric Acid Improves Glucose Tolerance and Insulin Sensitivity by Inhibiting Inflammation in High Fat Diet-Fed Mice

(2011) Jide Tian et al.   PLoS One

Combining Antigen-Based Therapy with GABA Treatment Synergistically Prolongs Survival of Transplanted ß-Cells in Diabetic NOD Mice

(2011) Jide Tian et al.   PLoS One

GABA Coordinates with Insulin in Regulating Secretory Function in Pancreatic INS-1 β-Cells

(2011) Paul Bansal et al.   PLoS One

GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes

(2011) N. Soltani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The caspase inhibitor IDN-6556 (PF3491390) improves marginal mass engraftment after islet transplantation in mice

(2011) Michael McCall et al.   SURGERY

 -Aminobutyric Acid (GABA) Is an Autocrine Excitatory Transmitter in Human Pancreatic  -Cells

(2010) M. Braun et al.   DIABETES

Caspase Inhibitor Therapy Synergizes With Costimulation Blockade to Promote Indefinite Islet Allograft Survival

(2010) J. A. Emamaullee et al.   DIABETES

An intrinsic GABAergic system in human lymphocytes

(2010) Leonardo Dionisio et al.   NEUROPHARMACOLOGY

Inhibitory role for GABA in autoimmune inflammation

(2010) R. Bhat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Positron Emission Tomography in Clinical Islet Transplantation

(2009) O. Eriksson et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Different Effects of FK506, Rapamycin, and Mycophenolate Mofetil on Glucose-Stimulated Insulin Release and Apoptosis in Human Islets

(2009) James D. Johnson et al.   CELL TRANSPLANTATION

Calcium signaling in the development and function of T-lineage cells

(2009) Masatsugu Oh-hora   IMMUNOLOGICAL REVIEWS

Role of NF-κB in β-cell death: Figure 1

(2008) Danielle Melloul   BIOCHEMICAL SOCIETY TRANSACTIONS

GABA, a natural immunomodulator of T lymphocytes

(2008) Helen Bjurstöm et al.   JOURNAL OF NEUROIMMUNOLOGY