Concise Review: Emerging Role of CD44 in Cancer Stem Cells: A Promising Biomarker and Therapeutic Target
出版年份 2015 全文链接
标题
Concise Review: Emerging Role of CD44 in Cancer Stem Cells: A Promising Biomarker and Therapeutic Target
作者
关键词
-
出版物
Stem Cells Translational Medicine
Volume 4, Issue 9, Pages 1033-1043
出版商
Wiley
发表日期
2015-07-02
DOI
10.5966/sctm.2015-0048
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- The Cancer Stem Cell Niche: How Essential Is the Niche in Regulating Stemness of Tumor Cells?
- (2015) Vicki Plaks et al. Cell Stem Cell
- Perspectives of CD44 targeting therapies
- (2014) V. Orian-Rousseau et al. ARCHIVES OF TOXICOLOGY
- The prognostic value of CD44 expression in gastric cancer: A meta-Analysis
- (2014) Yansu Chen et al. BIOMEDICINE & PHARMACOTHERAPY
- CD44 but not CD24 expression is related to poor prognosis in non-cardia adenocarcinoma of the stomach
- (2014) Xueyuan Cao et al. BMC GASTROENTEROLOGY
- Prognostic significance of CD44 variant 2 upregulation in colorectal cancer
- (2014) M Ozawa et al. BRITISH JOURNAL OF CANCER
- CD44v8-10 Is a Cancer-Specific Marker for Gastric Cancer Stem Cells
- (2014) W. M. Lau et al. CANCER RESEARCH
- Development and Applications of CRISPR-Cas9 for Genome Engineering
- (2014) Patrick D. Hsu et al. CELL
- Metastatic Stem Cells: Sources, Niches, and Vital Pathways
- (2014) Thordur Oskarsson et al. Cell Stem Cell
- CD44v6 Is a Marker of Constitutive and Reprogrammed Cancer Stem Cells Driving Colon Cancer Metastasis
- (2014) Matilde Todaro et al. Cell Stem Cell
- Osteopontin-CD44 Signaling in the Glioma Perivascular Niche Enhances Cancer Stem Cell Phenotypes and Promotes Aggressive Tumor Growth
- (2014) Alexander Pietras et al. Cell Stem Cell
- Regulation of alternative splicing of CD44 in cancer
- (2014) Lubomir Prochazka et al. CELLULAR SIGNALLING
- CD44-Targeted Docetaxel Conjugate for Cancer Cells and Cancer Stem-Like Cells: A Novel Hyaluronic Acid-Based Drug Delivery System
- (2014) Navid Goodarzi et al. Chemical Biology & Drug Design
- Expression of TNF-α and CD44 is implicated in poor prognosis, cancer cell invasion, metastasis and resistance to the sunitinib treatment in clear cell renal cell carcinomas
- (2014) Shuji Mikami et al. INTERNATIONAL JOURNAL OF CANCER
- A Novel CD44-binding Peptide from the Pro-Matrix Metalloproteinase-9 Hemopexin Domain Impairs Adhesion and Migration of Chronic Lymphocytic Leukemia (CLL) Cells
- (2014) Estefanía Ugarte-Berzal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dual drugs (microRNA-34a and paclitaxel)-loaded functional solid lipid nanoparticles for synergistic cancer cell suppression
- (2014) Sanjun Shi et al. JOURNAL OF CONTROLLED RELEASE
- Programmable RNA recognition and cleavage by CRISPR/Cas9
- (2014) Mitchell R. O’Connell et al. NATURE
- Prognostic value of CD44 and CD44v6 expression in patients with non-small cell lung cancer: meta-analysis
- (2014) Hao Jiang et al. TUMOR BIOLOGY
- Peptide-based vaccines for cancer therapy
- (2014) Giorgio Parmiani et al. Human Vaccines & Immunotherapeutics
- CD44 variant 9 expression in primary early gastric cancer as a predictive marker for recurrence
- (2013) K Hirata et al. BRITISH JOURNAL OF CANCER
- xCT Inhibition Depletes CD44v-Expressing Tumor Cells That Are Resistant to EGFR-Targeted Therapy in Head and Neck Squamous Cell Carcinoma
- (2013) M. Yoshikawa et al. CANCER RESEARCH
- Targeted Nanomedicine for Suppression of CD44 and Simultaneous Cell Death Induction in Ovarian Cancer: An Optimal Delivery of siRNA and Anticancer Drug
- (2013) V. Shah et al. CLINICAL CANCER RESEARCH
- CD44 integrates signaling in normal stem cell, cancer stem cell and (pre)metastatic niches
- (2013) Karin Williams et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- The effects of CD44 down-regulation on stem cell properties of head and neck cancer cell lines
- (2013) Fahad Kidwai et al. JOURNAL OF ORAL PATHOLOGY & MEDICINE
- Characteristics of CD44 alternative splice pattern in the course of human colorectal adenocarcinoma progression
- (2013) Balázs Bánky et al. Molecular Cancer
- Stem cell CD44v isoforms promote intestinal cancer formation in Apc(min) mice downstream of Wnt signaling
- (2013) J Zeilstra et al. ONCOGENE
- Helicobacter pylori generates cells with cancer stem cell properties via epithelial–mesenchymal transition-like changes
- (2013) E Bessède et al. ONCOGENE
- WNT5A Inhibits Metastasis and Alters Splicing of Cd44 in Breast Cancer Cells
- (2013) Wen Jiang et al. PLoS One
- Internalization of Met Requires the Co-Receptor CD44v6 and Its Link to ERM Proteins
- (2013) Susanne Hasenauer et al. PLoS One
- Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells
- (2013) M. A. Nieto SCIENCE
- Maintenance of the stemness in CD44+ HCT-15 and HCT-116 human colon cancer cells requires miR-203 suppression
- (2013) Sy-Yeuan Ju et al. Stem Cell Research
- Regulation of CD44 expression by tumor necrosis factor-α and its potential role in breast cancer cell migration
- (2012) Jun Li et al. BIOMEDICINE & PHARMACOTHERAPY
- miRNA-708 Control of CD44+ Prostate Cancer-Initiating Cells
- (2012) S. Saini et al. CANCER RESEARCH
- CD44s Regulates the TGF- -Mediated Mesenchymal Phenotype and Is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma
- (2012) K. Mima et al. CANCER RESEARCH
- Modulation of Glucose Metabolism by CD44 Contributes to Antioxidant Status and Drug Resistance in Cancer Cells
- (2012) M. Tamada et al. CANCER RESEARCH
- Pyruvate Kinase M2: Multiple Faces for Conferring Benefits on Cancer Cells
- (2012) M. Tamada et al. CLINICAL CANCER RESEARCH
- Epithelial to mesenchymal transition and cancer stem cell phenotypes leading to liver metastasis are abrogated by the novel TGFβ1-targeting peptides P17 and P144
- (2012) Idoia G. Zubeldia et al. EXPERIMENTAL CELL RESEARCH
- MicroRNA-199a targets CD44 to suppress the tumorigenicity and multidrug resistance of ovarian cancer-initiating cells
- (2012) Weiwei Cheng et al. FEBS Journal
- A phase II study of a urokinase-derived peptide (A6) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube, or primary peritoneal carcinoma: A Gynecologic Oncology Group study
- (2012) Michael A. Gold et al. GYNECOLOGIC ONCOLOGY
- Hyaluronan-CD44v3 Interaction with Oct4-Sox2-Nanog Promotes miR-302 Expression Leading to Self-renewal, Clonal Formation, and Cisplatin Resistance in Cancer Stem Cells from Head and Neck Squamous Cell Carcinoma
- (2012) Lilly Y. W. Bourguignon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ADAM10 promotes pituitary adenoma cell migration by regulating cleavage of CD44 and L1
- (2012) Yuan Pan et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Hyaluronic acid modified mesoporous silica nanoparticles for targeted drug delivery to CD44-overexpressing cancer cells
- (2012) Meihua Yu et al. Nanoscale
- CD44 promotes Kras-dependent lung adenocarcinoma
- (2012) P Zhao et al. ONCOGENE
- Hypoxia Regulates CD44 and Its Variant Isoforms through HIF-1α in Triple Negative Breast Cancer
- (2012) Balaji Krishnamachary et al. PLoS One
- Cancer stem cells and epithelial–mesenchymal transition: Concepts and molecular links
- (2012) Christina Scheel et al. SEMINARS IN CANCER BIOLOGY
- Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell
- (2012) Toshifumi Yae et al. Nature Communications
- CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth
- (2011) Takatsugu Ishimoto et al. CANCER CELL
- The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse
- (2011) Anna Merlos-Suárez et al. Cell Stem Cell
- MMP-9 induces CD44 cleavage and CD44 mediated cell migration in glioblastoma xenograft cells
- (2011) Chandramu Chetty et al. CELLULAR SIGNALLING
- Direct reprogramming of stem cell properties in colon cancer cells by CD44
- (2011) Ying-Jhen Su et al. EMBO JOURNAL
- CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression
- (2011) Rhonda L. Brown et al. JOURNAL OF CLINICAL INVESTIGATION
- Screening of Peptides Bound to Breast Cancer Stem Cell Specific Surface Marker CD44 by Phage Display
- (2011) Hye-Yeon Park et al. MOLECULAR BIOTECHNOLOGY
- A6 Peptide Activates CD44 Adhesive Activity, Induces FAK and MEK Phosphorylation, and Inhibits the Migration and Metastasis of CD44-Expressing Cells
- (2011) R. S. Piotrowicz et al. MOLECULAR CANCER THERAPEUTICS
- Interactions between cancer stem cells and their niche govern metastatic colonization
- (2011) Ilaria Malanchi et al. NATURE
- The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
- (2011) Can Liu et al. NATURE MEDICINE
- Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells
- (2011) L Y W Bourguignon et al. ONCOGENE
- MicroRNA-21 regulates the self-renewal of mouse spermatogonial stem cells
- (2011) Z. Niu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nuclear β-catenin and CD44 upregulation characterize invasive cell populations in non-aggressive MCF-7 breast cancer cells
- (2010) Masahiro Uchino et al. BMC CANCER
- The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
- (2010) John M. Heddleston et al. CELL CYCLE
- Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche
- (2010) Ahmed Mohyeldin et al. Cell Stem Cell
- Tumors as Organs: Complex Tissues that Interface with the Entire Organism
- (2010) Mikala Egeblad et al. DEVELOPMENTAL CELL
- Clinical significance of pAKT and CD44v6 overexpression with breast cancer
- (2010) Pei Yu et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis
- (2009) M. Tremmel et al. BLOOD
- CD44 targeting reduces tumour growth and prevents post-chemotherapy relapse of human breast cancers xenografts
- (2009) E Marangoni et al. BRITISH JOURNAL OF CANCER
- Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells
- (2009) Zhizhong Li et al. CANCER CELL
- Delivery of CD44 shRNA/Nanoparticles within Cancer Cells
- (2009) Suniti Misra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hyaluronan-CD44 Interaction with Protein Kinase Cϵ Promotes Oncogenic Signaling by the Stem Cell Marker Nanog and the Production of MicroRNA-21, Leading to Down-regulation of the Tumor Suppressor Protein PDCD4, Anti-apoptosis, and Chemotherapy Resistance in Breast Tumor Cells
- (2009) Lilly Y. W. Bourguignon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Acetylation and activation of STAT3 mediated by nuclear translocation of CD44
- (2009) Jia-Lin Lee et al. JOURNAL OF CELL BIOLOGY
- Identification of Gastric Cancer Stem Cells Using the Cell Surface Marker CD44
- (2009) Shigeo Takaishi et al. STEM CELLS
- Growth-Inhibitory and Tumor- Suppressive Functions of p53 Depend on Its Repression of CD44 Expression
- (2008) Samuel Godar et al. CELL
- DNA vaccination with CD44 variant isoform reduces mammary tumor local growth and lung metastasis
- (2008) Shulamit Batya Wallach-Dayan et al. MOLECULAR CANCER THERAPEUTICS
- The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
- (2008) Heather R. Christofk et al. NATURE
- Involvement of CD44, a molecule with a thousand faces, in cancer dissemination
- (2008) David Naor et al. SEMINARS IN CANCER BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started