Low Doses of Imatinib Induce Myelopoiesis and Enhance Host Anti-microbial Immunity

New tricks for old dogs: countering antibiotic resistance in tuberculosis with host-directed therapeutics

(2015) Thomas R. Hawn et al.   IMMUNOLOGICAL REVIEWS

High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias

(2014) Joseph Y. Shin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Kit Regulates Maintenance of Quiescent Hematopoietic Stem Cells

(2014) L. A. Thoren et al.   JOURNAL OF IMMUNOLOGY

Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

(2014) Katrin D. Mayer-Barber et al.   NATURE

TB: the Yin and Yang of lipid mediators

(2013) David M Tobin et al.   CURRENT OPINION IN PHARMACOLOGY

Revision of the Human Hematopoietic Tree: Granulocyte Subtypes Derive from Distinct Hematopoietic Lineages

(2013) André Görgens et al.   Cell Reports

The Systemic Immune State of Super-shedder Mice Is Characterized by a Unique Neutrophil-dependent Blunting of TH1 Responses

(2013) Smita Gopinath et al.   PLoS Pathogens

Improved survival in chronic myeloid leukemia since the introduction of imatinib therapy: a single-institution historical experience

(2012) H. Kantarjian et al.   BLOOD

Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections

(2012) David M. Tobin et al.   CELL

Back to the future: host-targeted chemotherapeutics for drug-resistant TB

(2012) Ruth J Napier et al.   Future Microbiology

Abelson Tyrosine Kinase Controls Phagosomal Acidification Required for Killing of Mycobacterium tuberculosis in Human Macrophages

(2012) H. Bruns et al.   JOURNAL OF IMMUNOLOGY

The Abl and Arg Kinases Mediate Distinct Modes of Phagocytosis and Are Required for Maximal Leishmania Infection

(2012) D. M. Wetzel et al.   MOLECULAR AND CELLULAR BIOLOGY

An image-based screen identifies a small molecule regulator of megakaryopoiesis

(2012) A. E. Boitano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Productive Replication of Ebola Virus Is Regulated by the c-Abl1 Tyrosine Kinase

(2012) M. Garcia et al.   Science Translational Medicine

Tolerability and safety of perampanel: two randomized dose-escalation studies

(2011) G. L. Krauss et al.   ACTA NEUROLOGICA SCANDINAVICA

Dasatinib or imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: 2-year follow-up from a randomized phase 3 trial (DASISION)

(2011) H. M. Kantarjian et al.   BLOOD

Imatinib-Sensitive Tyrosine Kinases Regulate Mycobacterial Pathogenesis and Represent Therapeutic Targets against Tuberculosis

(2011) Ruth J. Napier et al.   Cell Host & Microbe

Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection

(2011) Bisweswar Nandi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido

(2011) Vinod P Balachandran et al.   NATURE MEDICINE

Microparticles initiate decompression-induced neutrophil activation and subsequent vascular injuries

(2010) Stephen R. Thom et al.   JOURNAL OF APPLIED PHYSIOLOGY

CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow

(2010) Kyle J. Eash et al.   JOURNAL OF CLINICAL INVESTIGATION

Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity

(2010) Amie S. Corbin et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil Apoptosis: Relevance to the Innate Immune Response and Inflammatory Disease

(2010) Sarah Fox et al.   Journal of Innate Immunity

Variola and Monkeypox Viruses Utilize Conserved Mechanisms of Virion Motility and Release That Depend on Abl and Src Family Tyrosine Kinases

(2010) P. M. Reeves et al.   JOURNAL OF VIROLOGY

Abl Family Tyrosine Kinases Regulate Sialylated Ganglioside Receptors for Polyomavirus

(2010) A. I. Swimm et al.   JOURNAL OF VIROLOGY

Mechanisms of G-CSF-mediated hematopoietic stem and progenitor mobilization

(2010) A M Greenbaum et al.   LEUKEMIA

Role of Abl Kinase and the Wave2 Signaling Complex in HIV-1 Entry at a Post-Hemifusion Step

(2010) Brooke Harmon et al.   PLoS Pathogens

CXCR4 is a key regulator of neutrophil release from the bone marrow under basal and stress granulopoiesis conditions

(2009) Kyle J. Eash et al.   BLOOD

Aligning Antimicrobial Drug Discovery with Complex and Redundant Host-Pathogen Interactions

(2009) Sarah L. Lebeis et al.   Cell Host & Microbe

Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts

(2009) W. D. Bradley et al.   JOURNAL OF CELL SCIENCE

Genetic Inversion in Mast Cell-Deficient Wsh Mice Interrupts Corin and Manifests as Hematopoietic and Cardiac Aberrancy

(2008) Peter A. Nigrovic et al.   AMERICAN JOURNAL OF PATHOLOGY

Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study

(2008) R. A. Larson et al.   BLOOD

Population pharmacokinetics of imatinib mesylate and its metabolite in children and young adults

(2008) Divya Menon-Andersen et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

Granulocyte colony-stimulating factor: Molecular mechanisms of action during steady state and ‘emergency’ hematopoiesis

(2008) Athanasia D. Panopoulos et al.   CYTOKINE

RNA Interference Screen Identifies Abl Kinase and PDGFR Signaling in Chlamydia trachomatis Entry

(2008) Cherilyn A. Elwell et al.   PLoS Pathogens

RNAi Screen Reveals an Abl Kinase-Dependent Host Cell Pathway Involved in Pseudomonas aeruginosa Internalization

(2008) Julia F. Pielage et al.   PLoS Pathogens

Apoptosis: controlled demolition at the cellular level

(2007) Rebecca C. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY