Article
Chemistry, Analytical
Xinyang Zhu, Huanhuan Xing, Yuan Xue, Jing Li, Erkang Wang, Shaojun Dong
Summary: A chemical fixation strategy based on single-atom anchoring with metal-organic frameworks was proposed for solid-state electrochemiluminescence (ECL), using UiO-67(N) as the carrying matrix. The resulting Ru-UiO showed high ECL intensity and excellent stability in the presence of a coreactant at low concentrations, indicating great potential for the synthesis of solid-state ECL materials and their further utilization in ECL analysis.
ANALYTICAL CHEMISTRY
(2021)
Article
Immunology
Lisha Ma, Wensheng Wang, Lisha Li, Ying Chen, Binxuan Chen, Miaoli Shao, Yongjun Cheng, Renfang Zhou
Summary: This study evaluated a novel fully automated immunoturbidimetric assay for the detection of anti-CCP antibodies and compared it with the conventional ELISA method. The results showed that the four anti-CCP assays provided similar diagnostic information for rheumatoid arthritis (RA), with Qiangsheng's method being potentially more useful for large scale clinical screening due to its shorter testing time.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Chemistry, Analytical
Zhongnan Huang, Zhenglian Li, Yao Chen, Luyao Xu, Qianlong Xie, Haohua Deng, Wei Chen, Huaping Peng
Summary: This study presents a facile and highly efficient electrochemiluminescence (ECL) strategy for kanamycin detection based on gold nanocluster probes, utilizing the valence state effect of the gold nanoclusters. By inducing a valence state change in the chemically reduced gold nanoclusters, the detection of kanamycin with excellent sensitivity and extremely low detection limit was achieved without the need for signal amplification or aptamers. The proposed sensing platform showed high selectivity, an extremely broad linear range, and excellent recoveries for kanamycin detection in milk samples.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Zihui Liang, Peilin Wang, Zhenrun Li, Dongyu Wang, Qiang Ma
Summary: The combination of electrochemiluminescence technique and nanophotonics research has enabled a novel modulation strategy of polarization angle based on dynamically tunable few-layer metasurface. The redistribution of local electromagnetic field and energy in the ECL system amplified the ECL signal and modulated the polarization coupling angle. This study provides insights into metasurface-modulated optical signals and offers a new idea for constructing novel sensing platforms.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Zhongyan Xu, Zhihui Guo, Xingwang Zheng
Summary: In this study, a Co-Nx-C electrocatalyst was prepared on carbon nanotubes surface and treated with nitric acid or hydrochloric acid. Compared with Co-POC-R, the Co-POC-O electrocatalyst not only displayed excellent ORR performance but also enriched luminol via non-covalent bonds, significantly enhancing the ECL intensity.
ANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Physical
Fangxin Du, Yequan Chen, Chengda Meng, Baohua Lou, Wei Zhang, Guobao Xu
Summary: This review summarizes recent advances in ECL strategies with multiple-signal outputs, including ratiometric ECL, ECL multiplex immunoassay (MIA), and ECL imaging, discussing their signal generation strategies and applications in immunoassays. Challenges and prospects in this field are also addressed.
CURRENT OPINION IN ELECTROCHEMISTRY
(2021)
Article
Chemistry, Analytical
Zhengang Han, Juxia Wang, Peiyao Du, Jing Chen, Shuhui Huo, Huixia Guo, Xiaoquan Lu
Summary: Distinguishing between water (H2O) and deuteroxide (D2O) is a challenging task due to their similarities in size, shape, and chemical reactivity. This study investigates the enhanced optical properties of a water-soluble porphyrin in D2O and proposes a convenient method for distinguishing between H2O and D2O using electrochemiluminescence (ECL) analysis, which shows a lower detection limit.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Penghui Hu, Ruiyan Huang, Ye Xu, Tengfei Li, Jun Yin, Yu Yang, Yuan Liang, Xiaohan Mao, Li Ding, Chang Shu
Summary: In this study, ZnSe@ZnS quantum dots and Mn-doped ZnS quantum dots were synthesized and used as fluorophores to establish a ratiometric fluorescent assay for ALP activity detection. The method showed good sensitivity, specificity, and simplicity, and could be applied in clinical ALP activity detection and early disease diagnosis.
Article
Nanoscience & Nanotechnology
Hong-Rae Kim, Ji-Hong Bong, Jun-Hee Park, Zhiquan Song, Min-Jung Kang, Dong Hee Son, Jae-Chul Pyun
Summary: A hypersensitive photosensor based on CsPbBr3 quantum dots was developed for chemiluminescence immunoassays, showing high sensitivity and reduced trap states, making it feasible for detecting various diseases.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Analytical
Li Fu, Xuwen Gao, Shuangtian Dong, Hsien-Yi Hsu, Guizheng Zou
Summary: The study demonstrated successful achievement of aqueous monochromatic ECL with Met-capped Au-Ag BNCs as luminophores and TEOA as coreactant, resulting in efficient NIR-II ECL and its application in immunoassays. A sandwich immunocomplex immobilization strategy allowed selective detection of CA125 with a detection limit of 5 x 10(-5) U/mL.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Hui Wang, Cong-Hui Xu, Wei Zhao, Hong-Yuan Chen, Jing-Juan Xu
Summary: A simple and sensitive plasmonic probe (Au@FeOOH) was synthesized and used for alkaline phosphatase level detection, showing excellent linear range and detection limit. By using ΔR/G value as the analytical signal, the method effectively suppressed errors and exhibited excellent selectivity in complex biological serum samples, promising for early diagnosis of clinical diseases in the future.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Zihui Liang, Yixin Nie, Xin Zhang, Peilin Wang, Qiang Ma
Summary: A novel multiplex electrochemiluminescence polarization assay was developed to detect breast cancer-related genes BRCA1 and BRCA2 simultaneously. The study revealed the relation between the structure of metal nanomaterials and SPC-ECL, and a high polarization-resolved sensing system was designed to detect multitarget DNA. Polarization-based multiple ECL analysis has broad prospects in related cancer diagnosis and treatment evaluation.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Zhongyan Xu, Yanxin Zhou, Meihua Li, Zhihui Guo, Xingwang Zheng
Summary: A synergistic signal amplification pathway was established for luminol cathodic electrochemiluminescence (ECL) by decomposing H2O2 with catalase-like cobalt oxide nanorods (CoO NRs) and regenerating H2O2 with carbonate/bicarbonate buffer. Compared with other nanomaterial-modified electrodes, the CoO NR-modified electrode exhibited nearly 50 times stronger ECL intensity of the luminol-O2 system in a carbonate buffer solution. This work provides a new avenue to improve cathodic ECL and understand the mechanism of luminol cathodic ECL.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Natpapas Wiriyachaiporn, Siriwan Sirikaew, Nawakarn Chitchai, Pareena Janchompoo, Weerakanya Maneeprakorn, Suwussa Bamrungsap, Ekawat Pasomsub, Deanpen Japrung
Summary: The visual colorimetric rapid screening system, based on a lateral flow device, demonstrated good specificity to influenza A and B nucleoproteins without cross reactivity to other closely related respiratory viruses. It showed high sensitivity, detecting as low as 0.04 and 1 ng of influenza A and B protein content per test, respectively, within 10 minutes. Comparing to commercial tests, the system exhibited a four-to-eight-fold higher sensitivity and correlated well with standard molecular approaches in pre-clinical evaluation.
Article
Chemistry, Physical
Kenneth Chu, Jonathan R. Adsetts, Jing Ma, Congyang Zhang, Mahdi Hesari, Liuqing Yang, Zhifeng Ding
Summary: In this study, an absolute method using a photon-counting device was developed to determine the electrochemiluminescence quantum efficiency of coreactant systems. The efficiency of the Ru(bpy)(3)(2+)/ tri-n-propylamine (TPrA) ECL coreactant system was found to be 10.0 +/- 1.1%, showing a 3-fold enhancement compared to annihilation pathways. These findings suggest a promising approach in the expanding field of ECL research.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Chemistry, Analytical
George Z. Tsogas, Dimosthenis L. Giokas, Athanasios G. Vlessidis, Anastasia Badeka
ANALYTICAL LETTERS
(2016)
Article
Chemistry, Analytical
Asimina Voulgari, Vasiliki A. Gatselou, Foteini A. Kappi, Tatiana G. Choleva, George Z. Tsogas, Athanasios G. Vlessidis, Dimosthenis L. Giokas
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2017)
Article
Engineering, Environmental
Spyridoula P. Mandyla, George Z. Tsogas, Athanasios G. Vlessidis, Dimosthenis L. Giokas
JOURNAL OF HAZARDOUS MATERIALS
(2017)
Article
Chemistry, Analytical
Tatiana G. Choleva, Vasiliki A. Gatselou, George Z. Tsogas, Dimosthenis L. Giokas
Article
Chemistry, Analytical
Foteini A. Kappi, George Z. Tsogas, Dionysios C. Christodouleas, Dimosthenis L. Giokas
SENSORS AND ACTUATORS B-CHEMICAL
(2017)
Article
Chemistry, Analytical
Foteini A. Kappi, George A. Papadopoulos, George Z. Tsogas, Dimosthenis L. Giokas
Article
Chemistry, Analytical
Foteini A. Kappi, George Z. Tsogas, Anna-Maria Routsi, Dionysios C. Christodouleas, Dimosthenis L. Giokas
ANALYTICA CHIMICA ACTA
(2018)
Article
Chemistry, Analytical
Tatiana G. Choleva, George Z. Tsogas, Dimosthenis L. Giokas
Review
Chemistry, Analytical
George Giannoulas, George Z. Tsogas, Dimosthenis L. Giokas
Article
Environmental Sciences
Tatiana G. Choleva, George Z. Tsogas, Athanasios G. Vlessidis, Dimosthenis L. Giokas
ENVIRONMENTAL POLLUTION
(2020)
Article
Chemistry, Analytical
Maria Tarara, Dimosthenis L. Giokas, George Z. Tsogas
Summary: In this work, a new method for controlling fluid transport rate on paper-based analytical devices is explored. Delay and acceleration of fluid flow are achieved by wax printing linear patterns of variable width and overlaying hydrophobic stripes. The combination of these methods allows for a wide timing adjustment of fluid transport.
Article
Chemistry, Analytical
Panagiotis A. Bizirtsakis, Maria Tarara, Apostolia Tsiasioti, Paraskevas D. Tzanavaras, George Z. Tsogas
Summary: The study introduces a novel, direct and simple colorimetric method using microanalytical paper-based devices for selective determination of bismuth. This low-cost, easy-to-use and high-precision method does not require experimental apparatus, making it suitable for on-site analysis.
Article
Chemistry, Analytical
Maria Tarara, Apostolia Tsiasioti, Paraskevas D. Tzanavaras, George Z. Tsogas
Summary: This study presents a direct fluorimetric method for the selective determination of histidine using micro-analytical paper-based devices. The method is cost-effective and easy to use, making it suitable for practical applications.
Article
Chemistry, Multidisciplinary
Anastasia Kostara, George Z. Tsogas, Athanasios G. Vlessidis, Dimosthenis L. Giokas
Article
Chemistry, Analytical
George Z. Tsogas, Foteini A. Kappi, Athanasios G. Vlessidis, Dimosthenis L. Giokas
ANALYTICAL LETTERS
(2018)
Review
Chemistry, Analytical
Claudia Campanale, Silvia Galafassi, Francesca Di Pippo, Iulian Pojar, Carmine Massarelli, Vito Felice Uricchio
Summary: Biodegradable plastic mulches (BDMs) have the potential to be an eco-friendly alternative to conventional plastic mulches in agriculture. However, their long-term impacts on soil ecosystems are still uncertain, and further research is needed. Incorporating BDMs into the soil may stimulate microbial activity, but there is also a risk of incomplete degradation and release of residual microplastics and additives.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Xuechi Yin, Sijie Liu, Deepak Kukkar, Jianlong Wang, Daohong Zhang, Ki-Hyun Kim
Summary: The lateral flow immunoassay strip is a classic and dominant tool in point-of-care detection, known for its portability and simplicity. However, current colored nanomaterials used as signal labels in LFIA have limited sensing potential, leading to the recognition of composite nanoparticles as alternatives to enhance sensitivity, signal readout diversity, anti-matrix interference, and cost-effectiveness.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Yaxin Cao, Longyi Shao, Timothy P. Jones, Wenjing Deng, M. Santosh, Pengju Liu, Cheng-Xue Yang, Yaowei Li, Daizhou Zhang, Kelly Berube
Summary: The toxicity of fibrous particles in ambient air can be higher than other types of particles. Microfibers can be organic or inorganic and their presence in the atmosphere as a result of human activity raises concerns for environmental and public health. Accurate collection, identification, and understanding of the health hazards associated with these fibers are crucial for mitigation strategies and protection of public health.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Chenchen Xie, Chen Meng, Huilin Liu, Baoguo Sun
Summary: The development of food hazard factor (FHF) detection has been moving towards on-site inspection and mobile law enforcement, calling for simple, fast, and affordable analysis technology to ensure food safety and quality. This review comprehensively summarizes the progress in research on smartphone-assisted MIP optosensors, focusing on the key issues of accuracy and sensitivity.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Guillem Peris-Pastor, Cristian Azorin, Jose Grau, Juan L. Benede, Alberto Chisvert
Summary: Green Analytical Chemistry plays an important role in every stage of method development, including sample preparation. Extraction techniques have evolved from conventional ones to a variety of miniaturized techniques in order to enhance analytical performance and ensure safety for operators and the environment. Green metric tools are used to evaluate the impact and sustainability of methods, with AGREEprep selected as the most suitable tool for evaluating published methods in various applications. The miniaturization of sample preparation strategies has led to the use of less and safer solvents, reduced waste generation and energy consumption, and improved portability and throughput.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Helena Hruskova, Roman Reminek, Frantisek Foret
Summary: This review article summarizes the progress and recent studies in offline electromigration preparative techniques between 2018 and 2023. It covers various techniques including electrophoresis, free-flow electrophoresis, isoelectric focusing, and isotachophoresis, providing theoretical aspects, trends, and solutions to existing limitations in each technique.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Mayank Garg, Nicole Pamme
Summary: This review focuses on the removal strategies of templates from molecularly imprinted polymers (MIPs) used in diagnostic biosensors. Chemical-based and electrochemical-based template extraction approaches are summarized and evaluated, providing guidance for researchers in the fields of analytical chemistry, diagnostics, and materials science for the design of MIP-based sensors.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Ivneet Banga, Anirban Paul, Nathan Kodjo Mintah Churcher, Ruchita Mahesh Kumar, Sriram Muthukumar, Shalini Prasad
Summary: Breathomics is an emerging field that focuses on analyzing exhaled breath to diagnose and monitor respiratory diseases. Electrochemical sensors, with their high sensitivity, selectivity, and low cost, play a significant role in breathomics and can be integrated into portable devices for point-of-care diagnosis.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Fabjola Bilo, Paola Cirelli, Laura Borgese
Summary: This review explores the application of X-ray fluorescence (XRF) spectrometry for elemental analysis of particulate matter (PM) in air quality monitoring. It discusses the fundamentals of XRF, experimental configurations, PM sampling devices and substrate, sample preparation strategies, qualitative and quantitative analysis, as well as the challenges faced by XRF in becoming a reliable analytical technique for PM analysis.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Hakim Faraji
Summary: The dispersive liquid-liquid microextraction (DLLME) technique is widely popular in analytical chemistry due to its high efficiency, cost-effectiveness, and simplicity. Recent advancements have addressed the limitations of DLLME, incorporating greener solvents, innovative dispersion strategies, and simplified procedures. These changes have made DLLME a more sustainable and efficient technique.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Sherin F. Hammad, Inas A. Abdallah, Alaa Bedair, Reda M. Abdelhameed, Marcello Locatelli, Fotouh R. Mansour
Summary: Carbon nanomaterials (CNMs) have excellent capabilities in terms of adsorption, enhanced oxidation, and photocatalysis, attracting widespread attention in different fields. Metal-organic frameworks (MOFs) have been widely used due to their regular network structure, porous nature, and large specific surface area. However, the instability of MOFs in aqueous solutions limits their applications in chemical sensing. Recent studies have focused on increasing the stability of MOFs in water-based matrices through chemical modifications using CNMs.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Alexandra Pape, Oliver J. Schmitz
Summary: Low temperature plasmas based on dielectric barrier discharges have emerged as a recent development in ion source research. These ion sources are applicable to heat-sensitive analytes and can ionize a wide range of compounds. Despite intensive research on important parameters such as configuration, shape, size, and materials in the past two decades, the actual ionization mechanism for all plasma gases has not been fully elucidated. This review provides an overview of atmospheric pressure ion sources, with a focus on plasma and dielectric barrier discharge based ion sources, summarizing the reactions occurring in the plasma and discussing the applications developed by different research groups.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Hai Xiong, Fengli Li, Linyu Zeng, Qiyu Lei
Summary: This review provides an overview of the emerging trends in the use of functional COF nanomaterials as biosensors for DNA/RNA detection. It summarizes the construction of DNA/RNA hybridized COF nanoprobes and their potential applications in bioanalyte detection, biosensing, biomarker imaging, and clinical biomedicine.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Bing Yan
Summary: This article summarizes the recent progress in logic gate computing and operation based on multiple luminescence response and chemical sensing for lanthanide functionalized MOF hybrid systems. The article first describes multi-color luminescence and the subsequent multiple luminescence response. The basic concept of logic gate operation and the advantages of lanthanide-based hybrid materials are then introduced. Reports on logic gate operation using pure lanthanide MOFs are provided, followed by a detailed summary of logic gate operations using lanthanide functionalized MOF hybrid materials. Additionally, the article discusses the practical luminescent detection of analytes by correlating the luminescence responsive signals and the concentration of different analytes. Finally, the article concludes with a prospect for this topic.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Brij Mohan, Gurjaspreet Singh, Rakesh Kumar Gupta, Pawan Kumar Sharma, Alexander A. Solovev, Armando J. L. Pombeiro, Peng Ren
Summary: Porous materials, particularly hydrogen-bonded organic frameworks (HOFs), have gained significant attention due to their versatile applications and unique properties such as well-defined crystalline structure and easy regeneration processes. This article provides a comprehensive overview of HOFs, including synthesis methods, hydrogen bonding motifs, recent advancements, and potential applications, offering valuable guidance for further exploration in this dynamic field.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)