A Molecular Host Response Assay to Discriminate Between Sepsis and Infection-Negative Systemic Inflammation in Critically Ill Patients: Discovery and Validation in Independent Cohorts

The granulocyte orphan receptor CEACAM4 is able to trigger phagocytosis of bacteria

(2015) Julia Delgado Tasco´n et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Electronic Implementation of a Novel Surveillance Paradigm for Ventilator-associated Events. Feasibility and Validation

(2014) Peter M. C. Klein Klouwenberg et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Procalcitonin fails to predict bacteremia in SIRS patients: a cohort study

(2014) M. Hoenigl et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Assessment of empirical antibiotic therapy optimisation in six hospitals: an observational cohort study

(2014) Nikolay P Braykov et al.   LANCET INFECTIOUS DISEASES

Interobserver Agreement of Centers for Disease Control and Prevention Criteria for Classifying Infections in Critically Ill Patients*

(2013) Peter M. C. Klein Klouwenberg et al.   CRITICAL CARE MEDICINE

Net Reclassification Indices for Evaluating Risk Prediction Instruments

(2013) Kathleen F. Kerr et al.   EPIDEMIOLOGY

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

(2013) R. P. Dellinger et al.   INTENSIVE CARE MEDICINE

Severe Sepsis and Septic Shock

(2013) Derek C. Angus et al.   NEW ENGLAND JOURNAL OF MEDICINE

Perforin Is Detrimental to Controllinγ C. muridarum Replication In Vitro, but Not In Vivo

(2013) Raymond M. Johnson et al.   PLoS One

Combination Biomarkers to Diagnose Sepsis in the Critically Ill Patient

(2012) Sébastien Gibot et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

New Approaches to Sepsis: Molecular Diagnostics and Biomarkers

(2012) K. Reinhart et al.   CLINICAL MICROBIOLOGY REVIEWS

Development of asthma is determined by the age-dependent host response to respiratory virus infection: therapeutic implications

(2012) Erwin W Gelfand   CURRENT OPINION IN IMMUNOLOGY

Immunosenescence and herd immunity: with an ever-increasing aging population do we need to rethink vaccine schedules?

(2012) Pierre Olivier Lang et al.   Expert Review of Vaccines

Does This Adult Patient With Suspected Bacteremia Require Blood Cultures?

(2012) Bryan Coburn et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Sex affects immunity

(2012) Leesa M. Pennell et al.   JOURNAL OF AUTOIMMUNITY

Plac8-Dependent and Inducible NO Synthase-Dependent Mechanisms Clear Chlamydia muridarum Infections from the Genital Tract

(2012) R. M. Johnson et al.   JOURNAL OF IMMUNOLOGY

Trauma equals danger--damage control by the immune system

(2012) V. M. Stoecklein et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Dichotomizing a continuous outcome in cluster randomized trials: impact on power

(2012) Agnès Caille et al.   STATISTICS IN MEDICINE

Analysis by Categorizing or Dichotomizing Continuous Variables Is Inadvisable: An Example from the Natural History of Unruptured Aneurysms

(2011) O. Naggara et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

pROC: an open-source package for R and S+ to analyze and compare ROC curves

(2011) Xavier Robin et al.   BMC BIOINFORMATICS

Exon array data analysis using Affymetrix power tools and R statistical software

(2011) H. E. Lockstone   BRIEFINGS IN BIOINFORMATICS

Nonresolving Inflammation

(2010) Carl Nathan et al.   CELL

Long-term mortality and quality of life in sepsis: A systematic review*

(2010) Bradford D. Winters et al.   CRITICAL CARE MEDICINE

Molecular diagnostics of sepsis—Where are we today?☆

(2010) Michael Bauer et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Decrease of Plasma Platelet-Activating Factor Acetylhydrolase Activity in Lipopolysaccharide Induced Mongolian Gerbil Sepsis Model

(2010) Junwei Yang et al.   PLoS One

Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008

(2009) R Phillip Dellinger et al.   CRITICAL CARE MEDICINE

Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis

(2009) Rungnapa Pankla et al.   GENOME BIOLOGY

Estimating the capacity for improvement in risk prediction with a marker

(2008) W. Gu et al.   BIOSTATISTICS

A prospective, multicenter derivation of a biomarker panel to assess risk of organ dysfunction, shock, and death in emergency department patients with suspected sepsis

(2008) Nathan I. Shapiro et al.   CRITICAL CARE MEDICINE

Spectrum bias--why clinicians need to be cautious when applying diagnostic test studies

(2008) B. H Willis   FAMILY PRACTICE

Neurological injury markers in children with septic shock*

(2008) Angela A. Hsu et al.   Pediatric Critical Care Medicine