The Regulatory T Cell Lineage Factor Foxp3 Regulates Gene Expression through Several Distinct Mechanisms Mostly Independent of Direct DNA Binding

An atlas of mouse CD4+ T cell transcriptomes

(2015) Michael JT Stubbington et al.   Biology Direct

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

ImmPort: disseminating data to the public for the future of immunology

(2014) Sanchita Bhattacharya et al.   IMMUNOLOGIC RESEARCH

Continuous requirement for the TCR in regulatory T cell function

(2014) Andrew G Levine et al.   NATURE IMMUNOLOGY

CD4+ T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2

(2014) Nicole Boucheron et al.   NATURE IMMUNOLOGY

The Ubiquitin Ligase Stub1 Negatively Modulates Regulatory T Cell Suppressive Activity by Promoting Degradation of the Transcription Factor Foxp3

(2013) Zuojia Chen et al.   IMMUNITY

FOXP3: Genetic and epigenetic implications for autoimmunity

(2013) Hiroto Katoh et al.   JOURNAL OF AUTOIMMUNITY

Foxp3 Protein Stability Is Regulated by Cyclin-dependent Kinase 2

(2013) Peter A. Morawski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Self-Specific Memory Regulatory T Cells Protect Embryos at Implantation in Mice

(2013) T. Chen et al.   JOURNAL OF IMMUNOLOGY

Peripheral and Thymic Foxp3+ Regulatory T Cells in Search of Origin, Distinction, and Function

(2013) Chetan Dhamne et al.   Frontiers in Immunology

Geneious Basic: An integrated and extendable desktop software platform for the organization and analysis of sequence data

(2012) M. Kearse et al.   BIOINFORMATICS

Histone/protein deacetylases and T-cell immune responses

(2012) T. Akimova et al.   BLOOD

Foxp3 Exploits a Pre-Existent Enhancer Landscape for Regulatory T Cell Lineage Specification

(2012) Robert M. Samstein et al.   CELL

Silencing of the Il2 gene transcription is regulated by epigenetic changes in anergic T cells

(2012) Sanmay Bandyopadhyay et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development

(2012) Naganari Ohkura et al.   IMMUNITY

Helios Induces Epigenetic Silencing of Il2 Gene Expression in Regulatory T Cells

(2012) I. Baine et al.   JOURNAL OF IMMUNOLOGY

Transcription factor Foxp3 and its protein partners form a complex regulatory network

(2012) Dipayan Rudra et al.   NATURE IMMUNOLOGY

Forkhead Transcription Factor FOXP3 Upregulates CD25 Expression through Cooperation with RelA/NF-κB

(2012) Cristina Camperio et al.   PLoS One

Structural and Biological Features of FOXP3 Dimerization Relevant to Regulatory T Cell Function

(2012) Xiaomin Song et al.   Cell Reports

Comparative Genomics Reveals Key Gain-of-Function Events in Foxp3 during Regulatory T Cell Evolution

(2012) Kristian G. Andersen et al.   Frontiers in Immunology

Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells

(2011) Hozefa S. Bandukwala et al.   IMMUNITY

Sustained suppression by Foxp3+regulatory T cells is vital for infectious transplantation tolerance

(2011) Adrian R. Kendal et al.   JOURNAL OF EXPERIMENTAL MEDICINE

RNA sequencing reveals two major classes of gene expression levels in metazoan cells

(2011) D. Hebenstreit et al.   Molecular Systems Biology

Foxp3 Interacts with c-Rel to Mediate NF-κB Repression

(2011) Louiza Loizou et al.   PLoS One

Fast and SNP-tolerant detection of complex variants and splicing in short reads

(2010) T. D. Wu et al.   BIOINFORMATICS

EpiChIP: gene-by-gene quantification of epigenetic modification levels

(2010) Daniel Hebenstreit et al.   NUCLEIC ACIDS RESEARCH

Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization

(2009) J. van Loosdregt et al.   BLOOD

CTLA‐4 is required by CD4+CD25+Treg to control CD4+T‐cell lymphopenia‐induced proliferation

(2009) Dorothy K. Sojka et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Nonfunctional Regulatory T Cells and Defective Control of Th2 Cytokine Production in Natural Scurfy Mutant Mice

(2009) K. Lahl et al.   JOURNAL OF IMMUNOLOGY

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

(2009) Kajsa Wing et al.   NATURE IMMUNOLOGY

Three Distinct Domains Contribute to Nuclear Transport of Murine Foxp3

(2009) Wayne W. Hancock et al.   PLoS One

Eos Mediates Foxp3-Dependent Gene Silencing in CD4+ Regulatory T Cells

(2009) F. Pan et al.   SCIENCE

FoxP3 maintains Treg unresponsiveness by selectively inhibiting the promoter DNA-binding activity of AP-1

(2008) S.-M. Lee et al.   BLOOD

Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17–producing T cells

(2008) Fuping Zhang et al.   NATURE IMMUNOLOGY

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS

Signal processing by its coil zipper domain activates IKK 

(2008) S. Bloor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specific Immunosuppression with Inducible Foxp3-Transduced Polyclonal T cells

(2008) Kristian G Andersen et al.   PLOS BIOLOGY