Schisandrol B Protects Against Acetaminophen-Induced Hepatotoxicity by Inhibition of CYP-Mediated Bioactivation and Regulation of Liver Regeneration

FDA Asks Physicians to Stop Prescribing High-Dose Acetaminophen Products

(2014) Mike Mitka   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A perspective on the epidemiology of acetaminophen exposure and toxicity in the United States

(2014) Marissa Blieden et al.   Expert Review of Clinical Pharmacology

Schisandrin B attenuates acetaminophen-induced hepatic injury through heat-shock protein 27 and 70 in mice

(2013) Libo Li et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Transcription Pattern of p53-Targeted DNA Repair Genes in the Hypoxia-Tolerant Subterranean Mole Rat Spalax

(2013) Imad Shams et al.   JOURNAL OF MOLECULAR BIOLOGY

The Molecular Mechanisms of the Hepatoprotective Effect of Gomisin A against Oxidative Stress and Inflammatory Response in Rats with Carbon Tetrachloride-Induced Acute Liver Injury

(2012) Ryutaro Teraoka et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Nrf2-ARE pathway regulates induction of Sestrin-2 expression

(2012) Bo Yeon Shin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Liver Failure After Extended Hepatectomy in Mice Is Mediated by a p21-Dependent Barrier to Liver Regeneration

(2012) Kuno Lehmann et al.   GASTROENTEROLOGY

The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

(2012) Mitchell R. McGill et al.   JOURNAL OF CLINICAL INVESTIGATION

Pharmacokinetic Herb-Drug Interactions (Part 2): Drug Interactions Involving Popular Botanical Dietary Supplements and Their Clinical Relevance

(2012) Bill Gurley et al.   PLANTA MEDICA

Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo

(2012) Xiaoming Zhao et al.   TOXICOLOGY LETTERS

Current issues with acetaminophen hepatotoxicity—A clinically relevant model to test the efficacy of natural products

(2011) Hartmut Jaeschke et al.   LIFE SCIENCES

Synergism between p53 and Mcl-1 in protecting from hepatic injury, fibrosis and cancer

(2010) Shih-Yen Weng et al.   JOURNAL OF HEPATOLOGY

Structure and mechanism of the complex between cytochrome P4503A4 and ritonavir

(2010) I. F. Sevrioukova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Short-Term and Long-Term Pretreatment of Schisandra Lignans on Regulating Hepatic and Intestinal CYP3A in Rats

(2009) L. Lai et al.   DRUG METABOLISM AND DISPOSITION

Mechanism of protection by metallothionein against acetaminophen hepatotoxicity

(2009) Chieko Saito et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effects of CYP3A4 inducers with and without CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers

(2008) Samantha Abel et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Structures of Human Cytochrome P-450 2E1

(2008) Patrick R. Porubsky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacology of Schisandra chinensis Bail.: An overview of Russian research and uses in medicine

(2008) Alexander Panossian et al.   JOURNAL OF ETHNOPHARMACOLOGY

Prevention of acetaminophen (APAP)-induced hepatotoxicity by leflunomide via inhibition of APAP biotransformation to N-acetyl-p-benzoquinone imine

(2008) Su Ching Tan et al.   TOXICOLOGY LETTERS