Review
Chemistry, Organic
Marcos Escolano, Daniel Gavina, Javier Torres, Santiago Diaz-Oltra, Carlos del Pozo
Summary: The organocatalytic enantioselective desymmetrization reaction via intramolecular (hetero)Michael addition is an effective strategy for creating complex carbo- and heterocycles with multiple stereocenters in a simple manner. The main challenge lies in the design and synthesis of the starting materials.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Organic
Arup Jyoti Das, Raju Chouhan, Sajal Kumar Das
Summary: The IFCEAC reaction can efficiently and with high-yields synthesize nitrogen-containing fused ring systems, showing a wide substrate adaptability, but attention should be paid to the effects of the nature and position of the indole and epoxide substituents on the reaction yields.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Sk Asraf Ali, Anirban Bera, Mijanur Rahaman Molla, Shubhankar Samanta
Summary: This study reports an efficient synthetic strategy using Cu(I) catalyst for the synthesis of 3-substituted N-pyridinyl isoindolinones and N-aryl substituted isoindolinones. Unexpected synthesis of N-(1H-inden-1-yl)pyridin-2-amine derivatives from the same precursors was also documented using Cu(I) catalyst.
Article
Chemistry, Organic
Erich Ammon, Aleksandra Khomutetckaia, Alexander Villinger, Peter Ehlers, Peter Langer
Summary: Carba and heterocyclic benzoin derivatives were synthesized by Sonogashira coupling of alkynes with 1,2-dihaloalkenes and oxidation of the alkyne to a 1,2-diketone. Suzuki-Miyaura reaction and Pd-catalyzed nucleophilic addition to the carbonyl group were utilized for the formation of cyclic benzoin derivatives from the product of the Pd-catalyzed reaction with (2-bromophenyl)boronic acid in the presence of phenylacetylene. Previously unprecedented 5-hydroxy-5-phenylbenzo[b]naphtho[1,2-d]thiophene-6(5H)-ones and their regioisomers were prepared from 2,3-dibromobenzothiophene. Phenanthrene benzoin derivatives were synthesized from 2-bromo-1-iodobenzene.
Article
Chemistry, Organic
Genaro Carmona-Reyes, Ricardo Ballinas-Indili, Maria Elena Sanchez-Vergara, R. Alfredo Toscano, Cecilio Alvarez-Toledano
Summary: A novel intramolecular 1,6 oxa-Michael addition reaction was reported to obtain 5 and 6 member ring lactones in a one-pot reaction starting from activated pyridinyl propenones, without organic catalysis or bulky groups in the Michael acceptor. The regioselectivity of ring closure was found to be dependent on the propenone used.
TETRAHEDRON LETTERS
(2022)
Article
Optics
Jinfeng Zhao, Bing Jin
Summary: The study investigates the excited state proton transfer behavior of the novel HDBB system in different solvents, with a focus on the role of nonpolar solvents in enhancing the dual hydrogen bonds in the S-1 state. The results reveal that nonpolar solvents play a significant role in promoting the ESPT process of HDBB.
JOURNAL OF LUMINESCENCE
(2021)
Article
Chemistry, Organic
Maruti B. Yadav, Tae Jeong Yeon
Summary: In this study, we developed a novel method for synthesizing fused regioselective tricyclic furo[3,2-c]chromen and bicyclic imidazo[1,2-a]pyridine using a sequential intramolecular ring-closure-opening-closure pathway. The reaction was catalyzed by an organo-base catalyst and did not require any additional catalyst. The protocol showed good yields and provided practical access to these compounds.
JOURNAL OF HETEROCYCLIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Mitali Mishra, Nilima P. Mishra, Bishnu P. Raiguru, Tapaswini Das, Seetaram Mohapatra, Sabita Nayak, Deepak R. Mishra, Jasmine Panda, Dipak K. Sahoo
Summary: The efficient one-pot Michael addition-cyclization reaction under microwave irradiation has been developed for the synthesis of 6H-chromeno[4',3' : 4,5]imidazo[1,2-a]pyridine. This protocol allows for the synthesis of twenty structurally diversified imidazo[1,2-a]pyridines in high yield, showing the significant advantages of a wide range of functional groups tolerance, operational simplicity, and short reaction times.
Article
Chemistry, Multidisciplinary
Parikshit Moitra, Krishan Kumar, Paturu Kondaiah, Santanu Bhattacharya
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2014)
Article
Biochemistry & Molecular Biology
Thanikachalam Gunasundari, Srinivasan Chandrasekaran
CARBOHYDRATE RESEARCH
(2013)
Article
Biochemistry & Molecular Biology
Marie Lopez, Laurent F. Bornaghi, Sally-Ann Poulsen
CARBOHYDRATE RESEARCH
(2014)
Review
Biochemistry & Molecular Biology
Andrew G. Jamieson, Nicolas Boutard, David Sabatino, William D. Lubell
CHEMICAL BIOLOGY & DRUG DESIGN
(2013)
Article
Chemistry, Multidisciplinary
Jiangang Mao, Shuo-Qing Zhang, Bing-Feng Shi, Weiliang Bao
CHEMICAL COMMUNICATIONS
(2014)
Review
Chemistry, Multidisciplinary
Jiang Wang, Maria Sanchez-Rosello, Jose Luis Acena, Carlos del Pozo, Alexander E. Sorochinsky, Santos Fustero, Vadim A. Soloshonok, Hong Liu
Review
Chemistry, Multidisciplinary
Michal Szostak, Jeffrey Aube
Review
Chemistry, Multidisciplinary
Lorand Kiss, Ferenc Fueloep
Review
Chemistry, Multidisciplinary
Filip V. Toukach, Valentine P. Ananikov
CHEMICAL SOCIETY REVIEWS
(2013)
Review
Chemistry, Multidisciplinary
Marchello A. Cavitt, Lien H. Phun, Stefan France
CHEMICAL SOCIETY REVIEWS
(2014)
Article
Chemistry, Multidisciplinary
Sven P. Fritz, Johnathan V. Matlock, Eoghan M. McGarrigle, Varinder K. Aggarwal
CHEMISTRY-A EUROPEAN JOURNAL
(2013)
Article
Chemistry, Organic
Min Zhang, Junkai Guo, Yuefa Gong
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2014)
Article
Chemistry, Multidisciplinary
Julian C. Lo, Yuld Yabe, Phil S. Baran
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2014)
Review
Chemistry, Organic
Long-Wu Ye, Chao Shu, Fabien Gagosz
ORGANIC & BIOMOLECULAR CHEMISTRY
(2014)
Article
Chemistry, Organic
Fumiya Urabe, Shohei Miyamoto, Keisuke Takahashi, Jun Ishihara, Susumi Hatakeyama
Article
Chemistry, Organic
Fuying Zhu, Yamei Lin
Summary: In this study, a low-metal iron-supported catalyst (Fe20/NC-Mg) was reported for the efficient synthesis of quinoxaline compounds, using water as a solvent and without additional bases. The synergistic effect of FeNx site and Mg (OH)2 nanorods in the catalyst played a key role in achieving high yields (82-91%) in 16 examples. The gram-level synthesis and reusability of the catalysts after four cycles demonstrated its industrial application potential.
Article
Chemistry, Organic
Mikhail Kozlov, Alexey Tyurin, Andrey Dmitrenok, Vyacheslav Rusak, Aleksander Fedorov, Igor Zavarzin, Yulia Volkova
Summary: This study presents a novel and practical synthesis method for phosphorus-substituted 1,3,4-thiadiazolines using phosphorylthioformic acid hydrazides and ketones. The protocol demonstrates operational simplicity, availability of reagents, and tolerance towards different functional groups.
Article
Chemistry, Organic
Jisna Jose, Thomas Mathew
Summary: 2-Cyclopentenone and its derivatives are highly esteemed synthetic intermediates with exceptional utility in organic synthesis. They are favored structural motifs in numerous pharmaceutical drugs and natural products, highlighting their significance. The review discusses the various methods used to synthesize cyclopentenones from 2016 to 2023.
