标题
Next generation protein basedStreptococcus pneumoniaevaccines
作者
关键词
-
出版物
Human Vaccines & Immunotherapeutics
Volume 12, Issue 1, Pages 194-205
出版商
Informa UK Limited
发表日期
2015-11-06
DOI
10.1080/21645515.2015.1052198
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Higher levels of mucosal antibody to pneumococcal vaccine candidate proteins are associated with reduced acute otitis media caused by Streptococcus pneumoniae in young children
- (2015) Q Xu et al. Mucosal Immunology
- Trivalent pneumococcal protein recombinant vaccine protects against lethal Streptococcus pneumoniae pneumonia and correlates with phagocytosis by neutrophils during early pathogenesis
- (2015) Qingfu Xu et al. VACCINE
- Genetic conjugation of components in two pneumococcal fusion protein vaccines enhances paediatric mucosal immune responses
- (2015) Caroline Pope et al. VACCINE
- Synchrony in serum antibody response to conserved proteins ofStreptococcus pneumoniaein young children
- (2015) Dabin Ren et al. Human Vaccines & Immunotherapeutics
- Understanding the Ontogeny of the Immune System to Promote Immune-Mediated Health for Life
- (2015) Arnaud Marchant et al. Frontiers in Immunology
- The host immune dynamics of pneumococcal colonization: Implications for novel vaccine development
- (2015) M Nadeem Khan et al. Human Vaccines & Immunotherapeutics
- The adult nasopharyngeal microbiome as a determinant of pneumococcal acquisition
- (2015) Amelieke JH Cremers et al. Microbiome
- A comparative study of thin-section CT findings between seasonal influenza virus pneumonia andStreptococcus pneumoniaepneumonia
- (2014) A Ono et al. BRITISH JOURNAL OF RADIOLOGY
- Directing traffic: IL-17 and IL-22 coordinate pulmonary immune defense
- (2014) Jeremy P. McAleer et al. IMMUNOLOGICAL REVIEWS
- Human Antibodies to PhtD, PcpA, and Ply Reduce Adherence to Human Lung Epithelial Cells and Murine Nasopharyngeal Colonization by Streptococcus pneumoniae
- (2014) Ravinder Kaur et al. INFECTION AND IMMUNITY
- Pneumococcal PspA and PspC proteins: Potential vaccine candidates for experimental otitis media
- (2014) Patricia A. Schachern et al. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
- Influences of process and formulation parameters on powder flow properties and immunogenicity of spray dried polymer particles entrapping recombinant pneumococcal surface protein A
- (2014) Chakkumkal Anish et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Single-Cell Analysis of Innate Cytokine Responses to Pattern Recognition Receptor Stimulation in Children across Four Continents
- (2014) Kinga K. Smolen et al. JOURNAL OF IMMUNOLOGY
- Review: Current and new generation pneumococcal vaccines
- (2014) Charles Feldman et al. JOURNAL OF INFECTION
- An Ahemolytic Pneumolysin ofStreptococcus PneumoniaeManipulates Human Innate and CD4+T-Cell Responses and Reduces Resistance to Colonization in Mice in a Serotype-Independent Manner
- (2014) M. Nadeem Khan et al. JOURNAL OF INFECTIOUS DISEASES
- TaqMan real time RT-PCR assays for detecting ferret innate and adaptive immune responses
- (2014) Louise A. Carolan et al. JOURNAL OF VIROLOGICAL METHODS
- A Bivalent Vaccine Based on a Replication-Incompetent Influenza Virus Protects against Streptococcus pneumoniae and Influenza Virus Infection
- (2014) H. Katsura et al. JOURNAL OF VIROLOGY
- Lethal Coinfection of Influenza Virus and Streptococcus pneumoniae Lowers Antibody Response to Influenza Virus in Lung and Reduces Numbers of Germinal Center B Cells, T Follicular Helper Cells, and Plasma Cells in Mediastinal Lymph Node
- (2014) Yuet Wu et al. JOURNAL OF VIROLOGY
- Coinfection with Streptococcus pneumoniae Modulates the B Cell Response to Influenza Virus
- (2014) A. I. Wolf et al. JOURNAL OF VIROLOGY
- Safety, reactogenicity and immunogenicity of a novel pneumococcal protein-based vaccine in adults: A phase I/II randomized clinical study
- (2014) Geert Leroux-Roels et al. VACCINE
- Vaccination with a Streptococcus pneumoniae trivalent recombinant PcpA, PhtD and PlyD1 protein vaccine candidate protects against lethal pneumonia in an infant murine model
- (2014) David Verhoeven et al. VACCINE
- Safety and immunogenicity of an investigational vaccine containing two common pneumococcal proteins in toddlers: A phase II randomized clinical trial
- (2014) Roman Prymula et al. VACCINE
- Pneumolysin expression by streptococcus pneumoniae protects colonized mice from influenza virus-induced disease
- (2014) Amaya I. Wolf et al. VIROLOGY
- Optimal Serotype Compositions for Pneumococcal Conjugate Vaccination under Serotype Replacement
- (2014) Markku Nurhonen et al. PLoS Computational Biology
- Unbalanced Neonatal CD4+ T-Cell Immunity
- (2014) Isabelle Debock et al. Frontiers in Immunology
- The Role of Environmental Factors in Modulating Immune Responses in Early Life
- (2014) Duncan M. MacGillivray et al. Frontiers in Immunology
- Epidemiology of serotype 19A isolates from invasive pneumococcal disease in German children
- (2013) Mark van der Linden et al. BMC INFECTIOUS DISEASES
- Protection by BCG Vaccine Against Tuberculosis: A Systematic Review of Randomized Controlled Trials
- (2013) Punam Mangtani et al. CLINICAL INFECTIOUS DISEASES
- Therapeutic effects of garenoxacin in murine experimental secondary pneumonia by Streptococcus pneumoniae after influenza virus infection
- (2013) Yoshiko Fukuda et al. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
- CD4 T Cell Memory and Antibody Responses Directed against the Pneumococcal Histidine Triad Proteins PhtD and PhtE following Nasopharyngeal Colonization and Immunization and Their Role in Protection against Pneumococcal Colonization in Mice
- (2013) M. N. Khan et al. INFECTION AND IMMUNITY
- Pattern recognition receptor-mediated cytokine response in infants across 4 continents⋆
- (2013) Kinga K. Smolen et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Pneumococcal vaccine and opsonic pneumococcal antibody
- (2013) Joon Young Song et al. JOURNAL OF INFECTION AND CHEMOTHERAPY
- Broadly Protective Protein-Based Pneumococcal Vaccine Composed of Pneumolysin Toxoid–CbpA Peptide Recombinant Fusion Protein
- (2013) Beth Mann et al. JOURNAL OF INFECTIOUS DISEASES
- Clinical Implications of Pneumococcal Serotypes: Invasive Disease Potential, Clinical Presentations, and Antibiotic Resistance
- (2013) Joon Young Song et al. JOURNAL OF KOREAN MEDICAL SCIENCE
- CD4+ T-cell responses among adults and young children in response to Streptococcus pneumoniae and Haemophilus influenzae vaccine candidate protein antigens
- (2013) Sharad K. Sharma et al. VACCINE
- Co-colonization by Haemophilus influenzae with Streptococcus pneumoniae enhances pneumococcal-specific antibody response in young children
- (2013) Qingfu Xu et al. VACCINE
- Protein carriers of conjugate vaccines: Characteristics, development and clinical trials
- (2013) Michael E Pichichero Human Vaccines & Immunotherapeutics
- Kinetics of Coinfection with Influenza A Virus and Streptococcus pneumoniae
- (2013) Amber M. Smith et al. PLoS Pathogens
- Experimental Human Pneumococcal Carriage Augments IL-17A-dependent T-cell Defence of the Lung
- (2013) Adam K. A. Wright et al. PLoS Pathogens
- Viral and Bacterial Interactions in the Upper Respiratory Tract
- (2013) Astrid A. T. M. Bosch et al. PLoS Pathogens
- Variation between Populations in the Innate Immune Response to Vaccine Adjuvants
- (2013) Tobias R. Kollmann Frontiers in Immunology
- Differential Occurrence of Streptococcus pneumoniae Serotype 11E Between Asymptomatic Carriage and Invasive Pneumococcal Disease Isolates Reflects a Unique Model of Pathogen Microevolution
- (2012) J. J. Calix et al. CLINICAL INFECTIOUS DISEASES
- A century of pneumococcal vaccination research in humans
- (2012) J.D. Grabenstein et al. CLINICAL MICROBIOLOGY AND INFECTION
- Co-infection subverts mucosal immunity in the upper respiratory tract
- (2012) Rebeccah S Lijek et al. CURRENT OPINION IN IMMUNOLOGY
- Interactions between Streptococcus pneumoniae and influenza virus: a mutually beneficial relationship?
- (2012) Kirsty R Short et al. Future Microbiology
- Innate Immune Function by Toll-like Receptors: Distinct Responses in Newborns and the Elderly
- (2012) Tobias R. Kollmann et al. IMMUNITY
- Nasopharyngeal Colonization Elicits Antibody Responses to Staphylococcal and Pneumococcal Proteins That Are Not Associated with a Reduced Risk of Subsequent Carriage
- (2012) Sabine M. P. J. Prevaes et al. INFECTION AND IMMUNITY
- Neutralizing Antibodies Elicited by a Novel Detoxified Pneumolysin Derivative, PlyD1, Provide Protection against Both Pneumococcal Infection and Lung Injury
- (2012) Danielle Salha et al. INFECTION AND IMMUNITY
- Biochemical, Genetic, and Serological Characterization of Two Capsule Subtypes amongStreptococcus pneumoniaeSerotype 20 Strains
- (2012) Juan J. Calix et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mouse Models of Otitis Media
- (2012) Mahmood Fazal Bhutta OTOLARYNGOLOGY-HEAD AND NECK SURGERY
- Long-Term Effects of Pneumococcal Conjugate Vaccine on Nasopharyngeal Carriage of S. pneumoniae, S. aureus, H. influenzae and M. catarrhalis
- (2012) Judith Spijkerman et al. PLoS One
- Vaccine candidates PhtD and PhtE of Streptococcus pneumoniae are adhesins that elicit functional antibodies in humans
- (2012) M. Nadeem Khan et al. VACCINE
- Characterization of Th17 responses to Streptococcus pneumoniae in humans: Comparisons between adults and children in a developed and a developing country
- (2012) Anna Lundgren et al. VACCINE
- Safety and immunogenicity of pneumococcal protein vaccine candidates: Monovalent choline-binding protein A (PcpA) vaccine and bivalent PcpA–pneumococcal histidine triad protein D vaccine
- (2012) Monica Bologa et al. VACCINE
- The mucosal immune system of the respiratory tract
- (2012) Shintaro Sato et al. Current Opinion in Virology
- Antibody response toStreptococcus pneumoniaeproteins PhtD, LytB, PcpA, PhtE and Ply after nasopharyngeal colonization and acute otitis media in children
- (2012) Michael E. Pichichero et al. Human Vaccines & Immunotherapeutics
- Next generation pneumococcal vaccines
- (2011) Kristin L Moffitt et al. CURRENT OPINION IN IMMUNOLOGY
- Viral-Bacterial Interactions and Risk of Acute Otitis Media Complicating Upper Respiratory Tract Infection
- (2011) Melinda M. Pettigrew et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Long-term impairment of Streptococcus pneumoniae lung clearance is observed after initial infection with influenza A virus but not human metapneumovirus in mice
- (2011) H. P. Ludewick et al. JOURNAL OF GENERAL VIROLOGY
- The NLRP3 Inflammasome Is Differentially Activated by Pneumolysin Variants and Contributes to Host Defense in Pneumococcal Pneumonia
- (2011) M. Witzenrath et al. JOURNAL OF IMMUNOLOGY
- Immunological mechanisms of vaccination
- (2011) Bali Pulendran et al. NATURE IMMUNOLOGY
- Serum Antibody Response to Five Streptococcus pneumoniae Proteins During Acute Otitis Media in Otitis-prone and Non–otitis-prone Children
- (2011) Ravinder Kaur et al. PEDIATRIC INFECTIOUS DISEASE JOURNAL
- Community-Based Outbreaks in Vulnerable Populations of Invasive Infections Caused by Streptococcus pneumoniae Serotypes 5 and 8 in Calgary, Canada
- (2011) Otto G. Vanderkooi et al. PLoS One
- Pre-clinical evaluation of a 15-valent pneumococcal conjugate vaccine (PCV15-CRM197) in an infant-rhesus monkey immunogenicity model
- (2011) Julie M. Skinner et al. VACCINE
- A protein-based pneumococcal vaccine protects rhesus macaques from pneumonia after experimental infection with Streptococcus pneumoniae
- (2011) Philippe Denoël et al. VACCINE
- Characterisation of Regulatory T Cells in Nasal Associated Lymphoid Tissue in Children: Relationships with Pneumococcal Colonization
- (2011) Qibo Zhang et al. PLoS Pathogens
- Desert Dust Exposure Is Associated with Increased Risk of Asthma Hospitalization in Children
- (2010) Kumiko T. Kanatani et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Preclinical Evaluation of the Pht Proteins as Potential Cross-Protective Pneumococcal Vaccine Antigens
- (2010) Fabrice Godfroid et al. INFECTION AND IMMUNITY
- Influenza Infection Leads to Increased Susceptibility to Subsequent Bacterial Superinfection by Impairing NK Cell Responses in the Lung
- (2010) Cherrie-Lee Small et al. JOURNAL OF IMMUNOLOGY
- Bacterial Lipoproteins Differentially Regulate Human Primary and Memory CD4+ T and B Cell Responses to Pneumococcal Protein Antigens through Toll‐Like Receptor 2
- (2010) Qibo Zhang et al. JOURNAL OF INFECTIOUS DISEASES
- Safety and Antibody Response, Including Antibody Persistence for 5 Years, after Primary Vaccination or Revaccination with Pneumococcal Polysaccharide Vaccine in Middle‐Aged and Older Adults
- (2010) Daniel M. Musher et al. JOURNAL OF INFECTIOUS DISEASES
- IL-17: Important for Host Defense, Autoimmunity, and Allergy?
- (2010) F. Eun-Hyung Lee et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Transcriptional regulation, occurrence and putative role of the Pht family of Streptococcus pneumoniae
- (2010) S. Rioux et al. MICROBIOLOGY-SGM
- The dual nature of TH17 cells: shifting the focus to function
- (2010) William O'Connor et al. NATURE IMMUNOLOGY
- Serotype 19A Is the Most Common Serotype Causing Invasive Pneumococcal Infections in Children
- (2010) S. L. Kaplan et al. PEDIATRICS
- The immunising effect of pneumococcal nasopharyngeal colonisation; protection against future colonisation and fatal invasive disease
- (2009) Luke Richards et al. IMMUNOBIOLOGY
- Impaired Innate and Adaptive Immunity to Streptococcus pneumoniae and Its Effect on Colonization in an Infant Mouse Model
- (2009) D. Bogaert et al. INFECTION AND IMMUNITY
- Neonatal Innate TLR-Mediated Responses Are Distinct from Those of Adults
- (2009) T. R. Kollmann et al. JOURNAL OF IMMUNOLOGY
- T Cell Memory Response to Pneumococcal Protein Antigens in an Area of High Pneumococcal Carriage and Disease
- (2009) Marianne W. Mureithi et al. JOURNAL OF INFECTIOUS DISEASES
- Booster Vaccinations: Can Immunologic Memory Outpace Disease Pathogenesis?
- (2009) M. E. Pichichero PEDIATRICS
- Potential role for mucosally active vaccines against pneumococcal pneumonia
- (2009) Kondwani C. Jambo et al. TRENDS IN MICROBIOLOGY
- Pneumococcal carriage and acute otitis media induce serum antibodies to pneumococcal surface proteins CbpA and PhtD in children
- (2009) Birgit Simell et al. VACCINE
- Animal Models of Streptococcus pneumoniae Disease
- (2008) D. Chiavolini et al. CLINICAL MICROBIOLOGY REVIEWS
- Pneumolysin: A Double-Edged Sword During the Host-Pathogen Interaction
- (2008) Helen Marriott et al. CURRENT MOLECULAR MEDICINE
- IL-22 and inflammation: Leukin' through a glass onion
- (2008) Lauren A. Zenewicz et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Streptococcus pneumoniae Surface Protein PcpA Elicits Protection against Lung Infection and Fatal Sepsis
- (2008) D. T. Glover et al. INFECTION AND IMMUNITY
- Enhancing therapeutic vaccination by blocking PD-1–mediated inhibitory signals during chronic infection
- (2008) Sang-Jun Ha et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Host genetic susceptibility to pneumococcal and meningococcal disease: a systematic review and meta-analysis
- (2008) Matthijs C Brouwer et al. LANCET INFECTIOUS DISEASES
- Interleukin-17A Mediates Acquired Immunity to Pneumococcal Colonization
- (2008) Ying-Jie Lu et al. PLoS Pathogens
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now