标题
Expression quantitative trait locus analysis for translational medicine
作者
关键词
Transcript Abundance, Translational Medicine, Expression Quantitative Trait Locus, eQTL Analysis, Lymphoblast Cell Line
出版物
Genome Medicine
Volume 7, Issue 1, Pages -
出版商
Springer Nature
发表日期
2015-06-23
DOI
10.1186/s13073-015-0186-7
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- The role of regulatory variation in complex traits and disease
- (2015) Frank W. Albert et al. NATURE REVIEWS GENETICS
- A New Initiative on Precision Medicine
- (2015) Francis S. Collins et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
- (2015) et al. SCIENCE
- Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases
- (2014) Alexander Gusev et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Joint Analysis of Functional Genomic Data and Genome-wide Association Studies of 18 Human Traits
- (2014) Joseph K. Pickrell AMERICAN JOURNAL OF HUMAN GENETICS
- Functional annotation signatures of disease susceptibility loci improve SNP association analysis
- (2014) Edwin S Iversen et al. BMC GENOMICS
- Identification of candidate susceptibility genes for colorectal cancer through eQTL analysis
- (2014) Adria Closa et al. CARCINOGENESIS
- Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci
- (2014) Peter J. Castaldi et al. HUMAN MOLECULAR GENETICS
- Detection and replication of epistasis influencing transcription in humans
- (2014) Gibran Hemani et al. NATURE
- Another explanation for apparent epistasis
- (2014) Andrew R. Wood et al. NATURE
- Genetic and epigenetic fine mapping of causal autoimmune disease variants
- (2014) Kyle Kai-How Farh et al. NATURE
- Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins
- (2014) Alfonso Buil et al. NATURE GENETICS
- A general framework for estimating the relative pathogenicity of human genetic variants
- (2014) Martin Kircher et al. NATURE GENETICS
- Heritability and genomics of gene expression in peripheral blood
- (2014) Fred A Wright et al. NATURE GENETICS
- Genetic variability in the regulation of gene expression in ten regions of the human brain
- (2014) Adaikalavan Ramasamy et al. NATURE NEUROSCIENCE
- Large-Scale East-Asian eQTL Mapping Reveals Novel Candidate Genes for LD Mapping and the Genomic Landscape of Transcriptional Effects of Sequence Variants
- (2014) Maiko Narahara et al. PLoS One
- Impact of regulatory variation from RNA to protein
- (2014) A. Battle et al. SCIENCE
- Intersection of population variation and autoimmunity genetics in human T cell activation
- (2014) C. J. Ye et al. SCIENCE
- Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes
- (2014) T. Raj et al. SCIENCE
- Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells
- (2014) M. N. Lee et al. SCIENCE
- Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression
- (2014) B. P. Fairfax et al. SCIENCE
- Approaches for establishing the function of regulatory genetic variants involved in disease
- (2014) Julian Charles Knight Genome Medicine
- Gene expression profiles associated with acute myocardial infarction and risk of cardiovascular death
- (2014) Jinhee Kim et al. Genome Medicine
- Methylation QTLs Are Associated with Coordinated Changes in Transcription Factor Binding, Histone Modifications, and Gene Expression Levels
- (2014) Nicholas E. Banovich et al. PLoS Genetics
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
- (2014) Claudia Giambartolomei et al. PLoS Genetics
- Genetic Background Drives Transcriptional Variation in Human Induced Pluripotent Stem Cells
- (2014) Foad Rouhani et al. PLoS Genetics
- The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts
- (2014) James R Wagner et al. GENOME BIOLOGY
- Large Sample Size, Wide Variant Spectrum, and Advanced Machine-Learning Technique Boost Risk Prediction for Inflammatory Bowel Disease
- (2013) Zhi Wei et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genetic and Epigenetic Regulation of Human lincRNA Gene Expression
- (2013) Konstantin Popadin et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits
- (2013) O. Corradin et al. GENOME RESEARCH
- Genetics of rheumatoid arthritis contributes to biology and drug discovery
- (2013) Yukinori Okada et al. NATURE
- Transcriptome and genome sequencing uncovers functional variation in humans
- (2013) Tuuli Lappalainen et al. NATURE
- The Cancer Genome Atlas Pan-Cancer analysis project
- (2013) John N Weinstein et al. NATURE GENETICS
- Large-scale genotyping identifies 41 new loci associated with breast cancer risk
- (2013) Kyriaki Michailidou et al. NATURE GENETICS
- The Genotype-Tissue Expression (GTEx) project
- (2013) John Lonsdale et al. NATURE GENETICS
- Systematic identification of trans eQTLs as putative drivers of known disease associations
- (2013) Harm-Jan Westra et al. NATURE GENETICS
- Systems genetics approaches to understand complex traits
- (2013) Mete Civelek et al. NATURE REVIEWS GENETICS
- Pitfalls of predicting complex traits from SNPs
- (2013) Naomi R. Wray et al. NATURE REVIEWS GENETICS
- Coordinated Effects of Sequence Variation on DNA Binding, Chromatin Structure, and Transcription
- (2013) H. Kilpinen et al. SCIENCE
- Primate Transcript and Protein Expression Levels Evolve Under Compensatory Selection Pressures
- (2013) Z. Khan et al. SCIENCE
- Identification of Genetic Variants That Affect Histone Modifications in Human Cells
- (2013) G. McVicker et al. SCIENCE
- A Statistical Framework for Joint eQTL Analysis in Multiple Tissues
- (2013) Timothée Flutre et al. PLoS Genetics
- Congruence of Additive and Non-Additive Effects on Gene Expression Estimated from Pedigree and SNP Data
- (2013) Joseph E. Powell et al. PLoS Genetics
- Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression
- (2013) Vinod Kumar et al. PLoS Genetics
- Blood-Informative Transcripts Define Nine Common Axes of Peripheral Blood Gene Expression
- (2013) Marcela Preininger et al. PLoS Genetics
- Five Years of GWAS Discovery
- (2012) Peter M. Visscher et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Large-scale profiling and identification of potential regulatory mechanisms for allelic gene expression in colorectal cancer cells
- (2012) Robin Dong-Woo Lee et al. GENE
- Linking disease associations with regulatory information in the human genome
- (2012) M. A. Schaub et al. GENOME RESEARCH
- Annotation of functional variation in personal genomes using RegulomeDB
- (2012) A. P. Boyle et al. GENOME RESEARCH
- Evolutionary Meta-Analysis of Association Studies Reveals Ancient Constraints Affecting Disease Marker Discovery
- (2012) J. T. Dudley et al. MOLECULAR BIOLOGY AND EVOLUTION
- Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- (2012) Luke Jostins et al. NATURE
- Massively parallel functional dissection of mammalian enhancers in vivo
- (2012) Rupali P Patwardhan et al. NATURE BIOTECHNOLOGY
- Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles
- (2012) Benjamin P Fairfax et al. NATURE GENETICS
- Mapping cis- and trans-regulatory effects across multiple tissues in twins
- (2012) Elin Grundberg et al. NATURE GENETICS
- Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
- (2012) NATURE GENETICS
- Preparing for Precision Medicine
- (2012) Reza Mirnezami et al. NEW ENGLAND JOURNAL OF MEDICINE
- Population Differences in Transcript-Regulator Expression Quantitative Trait Loci
- (2012) Pierre R. Bushel et al. PLoS One
- Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection
- (2012) L. B. Barreiro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evidence for additive and interaction effects of host genotype and infection in malaria
- (2012) Y. Idaghdour et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
- (2012) M. T. Maurano et al. SCIENCE
- Patterns of Cis Regulatory Variation in Diverse Human Populations
- (2012) Barbara E. Stranger et al. PLoS Genetics
- Genetic control of gene expression in whole blood and lymphoblastoid cell lines is largely independent
- (2011) J. E. Powell et al. GENOME RESEARCH
- A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort
- (2011) D. M. Greenawalt et al. GENOME RESEARCH
- Gene expression profiling of CD8+ T cells predicts prognosis in patients with Crohn disease and ulcerative colitis
- (2011) James C. Lee et al. JOURNAL OF CLINICAL INVESTIGATION
- Integrated genomic analyses of ovarian carcinoma
- (2011) D. Bell et al. NATURE
- Exome sequencing as a tool for Mendelian disease gene discovery
- (2011) Michael J. Bamshad et al. NATURE REVIEWS GENETICS
- HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
- (2011) L. D. Ward et al. NUCLEIC ACIDS RESEARCH
- Inter-ethnic differences in lymphocyte sensitivity to glucocorticoids reflect variation in transcriptional response
- (2011) J C Maranville et al. PHARMACOGENOMICS JOURNAL
- Single-Tissue and Cross-Tissue Heritability of Gene Expression Via Identity-by-Descent in Related or Unrelated Individuals
- (2011) Alkes L. Price et al. PLoS Genetics
- Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology
- (2011) Elizabeth J. Rossin et al. PLoS Genetics
- Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA
- (2011) Rudolf S. N. Fehrmann et al. PLoS Genetics
- Gene Expression in Skin and Lymphoblastoid Cells: Refined Statistical Method Reveals Extensive Overlap in cis-eQTL Signals
- (2010) Jun Ding et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genevar: a database and Java application for the analysis and visualization of SNP-gene associations in eQTL studies
- (2010) T.-P. Yang et al. BIOINFORMATICS
- An Integrated Approach to Uncover Drivers of Cancer
- (2010) Uri David Akavia et al. CELL
- From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
- (2010) Kiran Musunuru et al. NATURE
- The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
- (2010) D. Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- The study of eQTL variations by RNA-seq: from SNPs to phenotypes
- (2010) Jacek Majewski et al. TRENDS IN GENETICS
- Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS
- (2010) Dan L. Nicolae et al. PLoS Genetics
- Accuracy of genome-wide imputation of untyped markers and impacts on statistical power for association studies
- (2009) Ke Hao et al. BMC GENETICS
- Geographical genomics of human leukocyte gene expression variation in southern Morocco
- (2009) Youssef Idaghdour et al. NATURE GENETICS
- Mapping complex disease traits with global gene expression
- (2009) William Cookson et al. NATURE REVIEWS GENETICS
- Systems medicine: the future of medical genomics and healthcare
- (2009) Charles Auffray et al. Genome Medicine
- Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions
- (2009) Soumya Raychaudhuri et al. PLoS Genetics
- Prediction of Cancer Driver Mutations in Protein Kinases
- (2008) A. Torkamani et al. CANCER RESEARCH
- A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus
- (2008) Damien Chaussabel et al. IMMUNITY
- Genetics of gene expression and its effect on disease
- (2008) Valur Emilsson et al. NATURE
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes
- (2008) K. Lage et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Revealing the architecture of gene regulation: the promise of eQTL studies
- (2008) Yoav Gilad et al. TRENDS IN GENETICS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started