Transient blocking of NK cell function with small molecule inhibitors for helper dependant adenoviral vector-mediated gene delivery

The activation status of human macrophages presenting antigen determines the efficiency of Th17 responses

(2015) Christina E. Arnold et al.   IMMUNOBIOLOGY

NF-κB pathways in hematological malignancies

(2014) Chiara Gasparini et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

NK Cell Responses to Simian Immunodeficiency Virus Vaginal Exposure in Naive and Vaccinated Rhesus Macaques

(2014) L. Shang et al.   JOURNAL OF IMMUNOLOGY

Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial

(2014) Robert E MacLaren et al.   LANCET

Ruxolitinib: Long-Term Management of Patients with Myelofibrosis and Future Directions in the Treatment of Myeloproliferative Neoplasms

(2014) A. Yacoub et al.   Current Hematologic Malignancy Reports

The JAK-inhibitor ruxolitinib impairs dendritic cell function in vitro and in vivo

(2013) A. Heine et al.   BLOOD

Ruxolitinib is a potent immunosuppressive compound: is it time for anti-infective prophylaxis?

(2013) A. Heine et al.   BLOOD

Natural killer cells regulate diverse T cell responses

(2013) Sarah Q. Crome et al.   TRENDS IN IMMUNOLOGY

Caffeic Acid Phenethyl Ester Suppresses the Production of Pro-inflammatory Cytokines in Hypertrophic Adipocytes through Lipopolysaccharide-Stimulated Macrophages

(2012) Sachiko Juman et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

AAV2 Gene Therapy Readministration in Three Adults with Congenital Blindness

(2012) J. Bennett et al.   Science Translational Medicine

Membrane-bound IL-15 stimulation on peripheral blood natural kiler progenitors leads to the generation of an adherent subset co-expressing dendritic cells and natural kiler functional markers

(2011) S. Negrini et al.   HAEMATOLOGICA

Personalized medicine: new genomics, old lessons

(2011) Kenneth Offit   HUMAN GENETICS

Interactions of Human Myeloid Cells with Natural Killer Cell Subsets In Vitro and In Vivo

(2011) Obinna Chijioke et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Comparing the Kinetics of NK Cells, CD4, and CD8 T Cells in Murine Cytomegalovirus Infection

(2011) T. E. Schlub et al.   JOURNAL OF IMMUNOLOGY

Genomic sequencing in clinical trials

(2011) Karen K Mestan et al.   Journal of Translational Medicine

Kinase domain mutations confer resistance to novel inhibitors targeting JAK2V617F in myeloproliferative neoplasms

(2011) A Deshpande et al.   LEUKEMIA

NKG2D Is Required for NK Cell Activation and Function in Response to E1-Deleted Adenovirus

(2010) J. Zhu et al.   JOURNAL OF IMMUNOLOGY

Natural killer cell is a major producer of interferon γ that is critical for the IL-12-induced anti-tumor effect in mice

(2009) Akio Uemura et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Clinical-grade ex vivo-expanded human natural killer cells up-regulate activating receptors and death receptor ligands and have enhanced cytolytic activity against tumor cells

(2009) Maria Berg et al.   CYTOTHERAPY

Proteasome inhibition induces apoptosis in primary human natural killer cells and suppresses NKp46-mediated cytotoxicity

(2009) X. Wang et al.   HAEMATOLOGICA

Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation

(2008) Jing Wu et al.   CELL RESEARCH

Comparison in the effects of IL-2, IL-12, IL-15 and IFNα on gene regulation of granzymes of human NK cell line NK-92

(2008) Bin Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

(2008) Nicholas D. Huntington et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Alveolar Macrophages Are a Major Determinant of Early Responses to Viral Lung Infection but Do Not Influence Subsequent Disease Development

(2008) P. K. Pribul et al.   JOURNAL OF VIROLOGY

A Critical Role for Type I IFN–dependent NK Cell Activation in Innate Immune Elimination of Adenoviral Vectors In Vivo

(2008) Jiangao Zhu et al.   MOLECULAR THERAPY

Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis

(2008) Albert M. Maguire et al.   NEW ENGLAND JOURNAL OF MEDICINE