Mesenchymal Stem/Stromal Cells Inhibit the NLRP3 Inflammasome by Decreasing Mitochondrial Reactive Oxygen Species

BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells

(2013) Eleni D. Lagadinou et al.   Cell Stem Cell

Stanniocalcin-1 Protects Retinal Ganglion Cells by Inhibiting Apoptosis and Oxidative Damage

(2013) Sang Jin Kim et al.   PLoS One

High levels of reactive oxygen species in gold nanoparticle-targeted cancer cells following femtosecond pulse irradiation

(2013) Limor Minai et al.   Scientific Reports

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

(2012) Kenichi Shimada et al.   IMMUNITY

Mesenchymal stromal cells: a key player in ‘innate tolerance’?

(2012) Francesco Dazzi et al.   IMMUNOLOGY

Stanniocalcin-1 Rescued Photoreceptor Degeneration in Two Rat Models of Inherited Retinal Degeneration

(2012) Gavin W Roddy et al.   MOLECULAR THERAPY

Human Mesenchymal Stem/Stromal Cells Cultured as Spheroids are Self-activated to Produce Prostaglandin E2 that Directs Stimulated Macrophages into an Anti-inflammatory Phenotype

(2012) Joni H. YlÖstalo et al.   STEM CELLS

Mesenchymal Stem Cells: Mechanisms of Inflammation

(2011) Nora G. Singer et al.   Annual Review of Pathology-Mechanisms of Disease

Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF- B signaling in resident macrophages

(2011) H. Choi et al.   BLOOD

Mitochondria: Sovereign of inflammation?

(2011) Jürg Tschopp   EUROPEAN JOURNAL OF IMMUNOLOGY

Innate and Adaptive Interferons Suppress IL-1α and IL-1β Production by Distinct Pulmonary Myeloid Subsets during Mycobacterium tuberculosis Infection

(2011) Katrin D. Mayer-Barber et al.   IMMUNITY

The inflammasome: an integrated view

(2011) Olaf Gross et al.   IMMUNOLOGICAL REVIEWS

Thrombospondin-1: Multiple Paths to Inflammation

(2011) Zenaida Lopez-Dee et al.   MEDIATORS OF INFLAMMATION

Mesenchymal Stem/Stromal Cells (MSCs): Role as Guardians of Inflammation

(2011) Darwin J Prockop et al.   MOLECULAR THERAPY

Mesenchymal Stromal Cells Protect Cancer Cells From ROS-induced Apoptosis and Enhance the Warburg Effect by Secreting STC1

(2011) Shinya Ohkouchi et al.   MOLECULAR THERAPY

Mitochondrial control of the NLRP3 inflammasome

(2011) Oliver Kepp et al.   NATURE IMMUNOLOGY

The Sterile Inflammatory Response

(2010) Kenneth L. Rock et al.   Annual Review of Immunology

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Inflammation 2010: New Adventures of an Old Flame

(2010) Ruslan Medzhitov   CELL

Mesenchymal Stromal Cells: Facilitators of Successful Transplantation?

(2010) Karen English et al.   Cell Stem Cell

Critical functions of priming and lysosomal damage for NLRP3 activation

(2010) Veit Hornung et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Signaling by ROS drives inflammasome activation

(2010) Fabio Martinon   EUROPEAN JOURNAL OF IMMUNOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Mouse Bone Marrow-Derived Mesenchymal Stromal Cells Turn Activated Macrophages into a Regulatory-Like Profile

(2010) Julian Maggini et al.   PLoS One

The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages

(2010) Marc Daigneault et al.   PLoS One

Anti-Inflammatory and Renal Protective Actions of Stanniocalcin-1 in a Model of Anti-Glomerular Basement Membrane Glomerulonephritis

(2009) Luping Huang et al.   AMERICAN JOURNAL OF PATHOLOGY

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Mesenchymal stem cell–educated macrophages: A novel type of alternatively activated macrophages

(2009) Jaehyup Kim et al.   EXPERIMENTAL HEMATOLOGY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Stanniocalcin-1 suppresses superoxide generation in macrophages through induction of mitochondrial UCP2

(2009) Yanlin Wang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes

(2009) Greta Guarda et al.   NATURE

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

(2008) Krisztián Németh et al.   NATURE MEDICINE

Multipotent Stromal Cells Are Activated to Reduce Apoptosis in Part by Upregulation and Secretion of Stanniocalcin-1

(2008) Gregory J. Block et al.   STEM CELLS