Human Mesenchymal Stem/Stromal Cells Cultured as Spheroids are Self-activated to Produce Prostaglandin E2 that Directs Stimulated Macrophages into an Anti-inflammatory Phenotype

Harnessing the Mesenchymal Stem Cell Secretome for the Treatment of Cardiovascular Disease

(2012) Sudhir H. Ranganath et al.   Cell Stem Cell

Mesenchymal stem cells enhance survival and bacterial clearance in murineEscherichia colipneumonia

(2012) Naveen Gupta et al.   THORAX

Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF- B signaling in resident macrophages

(2011) H. Choi et al.   BLOOD

Scaffold-free culture of mesenchymal stem cell spheroids in suspension preserves multilineage potential

(2011) Priya R. Baraniak et al.   CELL AND TISSUE RESEARCH

The MSC: An Injury Drugstore

(2011) Arnold I. Caplan et al.   Cell Stem Cell

3-D spheroid culture of bone marrow mesenchymal stem cell of rhesus monkey with improved multi-differentiation potential to epithelial progenitors and neuron in vitro

(2011) Yuan Jing et al.   CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Turning round: multipotent stromal cells, a three-dimensional revolution?

(2011) Fatima A. Saleh et al.   CYTOTHERAPY

Cross-talk between human mesenchymal stem/progenitor cells (MSCs) and rat hippocampal slices in LPS-stimulated cocultures: the MSCs are activated to secrete prostaglandin E2

(2011) Jessica E. Foraker et al.   JOURNAL OF NEUROCHEMISTRY

Mesenchymal Stem/Stromal Cells (MSCs): Role as Guardians of Inflammation

(2011) Darwin J Prockop et al.   MOLECULAR THERAPY

Action at a Distance: Systemically Administered Adult Stem/Progenitor Cells (MSCs) Reduce Inflammatory Damage to the Cornea Without Engraftment and Primarily by Secretion of TNF-α Stimulated Gene/Protein 6

(2011) Gavin W. Roddy et al.   STEM CELLS

Mesenchymal Stem Cells Reduce Inflammation while Enhancing Bacterial Clearance and Improving Survival in Sepsis

(2010) Shirley H. J. Mei et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Evolving paradigms for repair of tissues by adult stem/progenitor cells (MSCs)

(2010) Darwin J. Prockop et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Stress responses: the contribution of prostaglandin E2 and its receptors

(2010) Tomoyuki Furuyashiki et al.   Nature Reviews Endocrinology

Pro-Inflammatory Cytokines, IFNγ and TNFα, Influence Immune Properties of Human Bone Marrow and Wharton Jelly Mesenchymal Stem Cells Differentially

(2010) S. Jyothi Prasanna et al.   PLoS One

Mouse Bone Marrow-Derived Mesenchymal Stromal Cells Turn Activated Macrophages into a Regulatory-Like Profile

(2010) Julian Maggini et al.   PLoS One

IL-6-Dependent PGE2 Secretion by Mesenchymal Stem Cells Inhibits Local Inflammation in Experimental Arthritis

(2010) Carine Bouffi et al.   PLoS One

Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties

(2010) T. J. Bartosh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

3D spheroid culture system on micropatterned substrates for improved differentiation efficiency of multipotent mesenchymal stem cells

(2009) Wenjie Wang et al.   BIOMATERIALS

MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2

(2009) G. M. Spaggiari et al.   BLOOD

Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6

(2009) Ryang Hwa Lee et al.   Cell Stem Cell

Induction of Transglutaminase 2 by a Liver X Receptor/Retinoic Acid Receptor α Pathway Increases the Clearance of Apoptotic Cells by Human Macrophages

(2009) Cédric Rébé et al.   CIRCULATION RESEARCH

Human bone marrow mesenchymal stem cells differentiate into insulin-producing cells upon microenvironmental manipulation in vitro

(2009) Qiu-Ping Xie et al.   DIFFERENTIATION

Differentiation of synovial CD-105+human mesenchymal stem cells into chondrocyte-like cells through spheroid formation

(2009) M.C. Arufe et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Spherically Symmetric Mesenchymal Stromal Cell Bodies Inherent with Endogenous Extracellular Matrices for Cellular Cardiomyoplasty

(2009) Chung-Chi Wang et al.   STEM CELLS

Species Variation in the Mechanisms of Mesenchymal Stem Cell-Mediated Immunosuppression

(2009) Guangwen Ren et al.   STEM CELLS

Dynamic Three-Dimensional Culture Methods Enhance Mesenchymal Stem Cell Properties and Increase Therapeutic Potential

(2009) Jessica E. Frith et al.   TISSUE ENGINEERING PART C-METHODS

Enhanced recovery of mechanical function in the canine heart by seeding an extracellular matrix patch with mesenchymal stem cells committed to a cardiac lineage

(2008) Irina A. Potapova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The CD34-like protein PODXL and  6-integrin (CD49f) identify early progenitor MSCs with increased clonogenicity and migration to infarcted heart in mice

(2008) R. H. Lee et al.   BLOOD

Culturing of Human Mesenchymal Stem Cells as Three-dimensional Aggregates Induces Functional Expression of CXCR4 That Regulates Adhesion to Endothelial Cells

(2008) Irina A. Potapova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

(2008) Krisztián Németh et al.   NATURE MEDICINE

Leukemia Inhibitory Factor Secretion is a Predictor and Indicator of Early Progenitor Status in Adult Bone Marrow Stromal Cells

(2008) Mandolin J. Whitney et al.   TISSUE ENGINEERING PART A