Notch1 Stimulation Induces a Vascularization Switch With Pericyte-Like Cell Differentiation of Glioblastoma Stem Cells

Level of Notch activation determines the effect on growth and stem cell-like features in glioblastoma multiforme neurosphere cultures

(2013) Karina Kristoffersen et al.   CANCER BIOLOGY & THERAPY

Glioblastoma Stem Cells Generate Vascular Pericytes to Support Vessel Function and Tumor Growth

(2013) Lin Cheng et al.   CELL

A High Notch Pathway Activation Predicts Response to γ Secretase Inhibitors in Proneural Subtype of Glioma Tumor-Initiating Cells

(2013) Norihiko Saito et al.   STEM CELLS

Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited

(2012) Karl H. Plate et al.   ACTA NEUROPATHOLOGICA

Mechanisms of Glioma-Associated Neovascularization

(2012) Matthew E. Hardee et al.   AMERICAN JOURNAL OF PATHOLOGY

Notch and TGFβ Form a Reciprocal Positive Regulatory Loop that Suppresses Murine Prostate Basal Stem/Progenitor Cell Activity

(2012) Joseph M. Valdez et al.   Cell Stem Cell

Epigenetic regulation of mmp-9 gene expression

(2012) Marilyne Labrie et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Quest for Self-Identity: Not All Cancer Stem Cells Are the Same

(2012) A. B. Hjelmeland et al.   CLINICAL CANCER RESEARCH

Botch Promotes Neurogenesis by Antagonizing Notch

(2012) Zhikai Chi et al.   DEVELOPMENTAL CELL

Cell death and neuronal differentiation of glioblastoma stem-like cells induced by neurogenic transcription factors

(2012) Pierre-Olivier Guichet et al.   GLIA

Primary brain tumours in adults

(2012) Damien Ricard et al.   LANCET

The Notch signalling system: recent insights into the complexity of a conserved pathway

(2012) K. G. Guruharsha et al.   NATURE REVIEWS GENETICS

Endothelial Cells Create a Stem Cell Niche in Glioblastoma by Providing NOTCH Ligands That Nurture Self-Renewal of Cancer Stem-Like Cells

(2011) T. S. Zhu et al.   CANCER RESEARCH

Cancer stem cells in gliomas: Identifying and understanding the apex cell in cancer's hierarchy

(2011) Monica Venere et al.   GLIA

A distinct subset of glioma cell lines with stem cell-like properties reflects the transcriptional phenotype of glioblastomas and overexpresses CXCR4 as therapeutic target

(2011) Alexander Schulte et al.   GLIA

Oncogenic and tumor suppressor functions of Notch in cancer: it’s NOTCH what you think: Table I.

(2011) Camille Lobry et al.   JOURNAL OF EXPERIMENTAL MEDICINE

siRNA targeting Notch-1 decreases glioma stem cell proliferation and tumor growth

(2011) Jianpeng Wang et al.   MOLECULAR BIOLOGY REPORTS

Twisted tango: brain tumor neurovascular interactions

(2011) Anita B Hjelmeland et al.   NATURE NEUROSCIENCE

Normalization of the Vasculature for Treatment of Cancer and Other Diseases

(2011) Shom Goel et al.   PHYSIOLOGICAL REVIEWS

A Critical Requirement for Notch Signaling in Maintenance of the Quiescent Skeletal Muscle Stem Cell State

(2011) Philippos Mourikis et al.   STEM CELLS

Notch Signaling Is Necessary to Maintain Quiescence in Adult Muscle Stem Cells

(2011) Christopher R.R. Bjornson et al.   STEM CELLS

Physiology and pathophysiology of matrix metalloproteases

(2010) T. Klein et al.   AMINO ACIDS

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Angiogenesis: A Team Effort Coordinated by Notch

(2009) L.-K. Phng et al.   DEVELOPMENTAL CELL

The multiple functions of Numb

(2009) Alberto Gulino et al.   EXPERIMENTAL CELL RESEARCH

Malignant cell-derived PlGF promotes normalization and remodeling of the tumor vasculature

(2009) E.-M. Hedlund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diverse roles of the vasculature within the neural stem cell niche

(2009) Joshua S Goldberg et al.   Regenerative Medicine

TGF-αinduces upregulation and nuclear translocation of Hes1 in glioma cell

(2008) Yingfeng Zheng et al.   CELL BIOCHEMISTRY AND FUNCTION

Dimorphic effects of Notch signaling in bone homeostasis

(2008) Feyza Engin et al.   NATURE MEDICINE

SOX2Silencing in Glioblastoma Tumor-Initiating Cells Causes Stop of Proliferation and Loss of Tumorigenicity

(2008) Rosaria Maria Rita Gangemi et al.   STEM CELLS